Product image of Lansoprazol "doc" (Lansoprazole) supplied by GNH India

Lansoprazol "doc"

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazol "doc" (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazol "doc", is a proton pump inhibitor presented as a tablet for oral use. It reduces gastric acid production and is used to manage conditions such as gastro‑esophageal reflux disease, peptic ulcer disease, and Zollinger‑Ellison syndrome in adult patients.

GNH India supplies Lansoprazol "doc" as a licensed, GDP‑compliant international pharmaceutical product to hospitals, pharmacies, clinics and other health‑care institutions worldwide, ensuring consistent quality and regulatory compliance. The company handles export logistics, documentation and post‑delivery support for global partners.

Manufacturer / TM Owner

Doc Generici S.R.L.

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Indications & Clinical Uses

Lansoprazole is indicated for several acid‑related gastrointestinal conditions where suppression of gastric secretion is required.

  • Gastro‑esophageal reflux disease (GERD): provides symptomatic relief and promotes healing of esophageal irritation.
  • Peptic ulcer disease: supports ulcer healing and reduces risk of recurrence.
  • Helicobacter pylori eradication (in combination therapy): enhances eradication rates when used with antibiotics.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid secretion associated with gastrin‑producing tumors.

How It Works

  • Lansoprazole irreversibly binds to the H+/K+ ATPase enzyme, also known as the gastric proton pump, located on the secretory surface of parietal cells. By inhibiting this final step of acid production, it markedly reduces both basal and stimulated gastric acid secretion, leading to increased gastric pH and allowing mucosal healing in acid‑related disorders.

Side Effects

Lansoprazole is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: loose stools, often transient.
  • Nausea: occasional stomach discomfort.
  • Abdominal pain: cramping or discomfort.
  • Flatulence: increased gas.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Severe allergic reactions: rash, swelling, anaphylaxis.
  • Clostridioides difficile infection: severe colitis.
  • Low magnesium levels: muscle cramps, arrhythmia.
  • Vitamin B12 deficiency: anemia, neuropathy.
  • Elevated liver enzymes: hepatitis signs.
  • Acute pancreatitis: abdominal pain radiating to back.

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Assess renal function: adjust use in severe renal impairment.
  • Monitor for drug interactions: especially with clopidogrel, warfarin, methotrexate.
  • Use caution in elderly: higher risk of bone fractures.
  • Avoid prolonged use without supervision: risk of nutrient deficiencies.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Lansoprazole may interact with several medicines; categorize them as follows.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet effect.
  • Atazanavir: decreased absorption of atazanavir.
  • Methotrexate: increased toxicity.

Moderate Interactions (Monitor Closely)

  • Warfarin: variable INR changes.
  • Digoxin: reduced serum levels.
  • Ciclosporin: increased blood concentrations.

Frequently Asked Questions

Lansoprazol "doc" contains the active ingredient lansoprazole, a proton pump inhibitor used to treat conditions caused by excess stomach acid, such as gastro‑esophageal reflux disease, peptic ulcer disease, Helicobacter pylori infection (as part of combination therapy), and Zollinger‑Ellison syndrome.

Lansoprazole works by irreversibly inhibiting the H+/K+ ATPase enzyme, the gastric proton pump in parietal cells. This blockade stops the final step of acid secretion, leading to a sustained increase in gastric pH and allowing damaged mucosa to heal.

The appropriate dose and treatment duration are determined by the prescribing healthcare professional based on the specific indication, patient age, renal function and other clinical factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for lansoprazole in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lansoprazole belongs to the same class as omeprazole, esomeprazole and pantoprazole. All PPIs share a similar mechanism of action, but differences exist in pharmacokinetics, drug‑interaction profiles and dosing convenience. Lansoprazole is often chosen for its once‑daily dosing and a favorable interaction profile with certain antivirals.

Store the tablets at ambient temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and light. Do not store in bathrooms or near heat sources, and keep out of reach of children.

Lansoprazol "doc" is taken orally as a tablet. Swallow the tablet whole with a glass of water, preferably before a meal, unless the prescriber provides different instructions. Do not crush, chew, or split the tablet unless advised.

Serious risks include severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, low magnesium levels that can cause muscle cramps or cardiac arrhythmias, vitamin B12 deficiency with long‑term use, and rare cases of liver injury or pancreatitis. Patients should seek medical attention if they experience these symptoms.

Individuals with a known hypersensitivity to lansoprazole or other proton pump inhibitors should avoid the product. It is also contraindicated in patients with severe liver disease or those who have experienced serious adverse reactions to similar medications. A healthcare professional should evaluate suitability before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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