Product image of Lansoprazol Flas Stada (Lansoprazole) supplied by GNH India

Lansoprazol Flas Stada

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazol Flas Stada (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazol Flas Stada, is a proton pump inhibitor presented as an unknown strength/oral form for oral use. It treats acid‑related disorders such as gastro‑oesophageal reflux disease, peptic ulcer disease, and is employed in Helicobacter pylori eradication regimens.

GNH India supplies Lansoprazol Flas Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratorio Stada, S.L.

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Indications & Clinical Uses

Lansoprazole acts on the gastric proton pump to reduce acid secretion, making it useful for several acid‑related conditions.

  • Gastro‑oesophageal reflux disease (GERD): relieves heartburn and esophageal irritation by lowering gastric acidity.
  • Peptic ulcer disease: promotes ulcer healing and prevents recurrence by maintaining a less acidic gastric environment.
  • Helicobacter pylori eradication: used in combination therapy to increase the effectiveness of antibiotics.
  • NSAID‑induced ulcer prophylaxis: reduces the risk of ulcer formation in patients taking non‑steroidal anti‑inflammatory drugs.

How It Works

  • Lansoprazole irreversibly binds to the H+/K+ ATPase enzyme (gastric proton pump) located on the secretory surface of parietal cells. By inhibiting this final step of acid production, it markedly reduces basal and stimulated gastric acid secretion, thereby increasing gastric pH and allowing mucosal healing.

Side Effects

Lansoprazole is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhoea: loose stools, usually transient.
  • Abdominal pain: discomfort or cramping in the stomach area.
  • Nausea: feeling of sickness, sometimes with vomiting.
  • Flatulence: increased gas production.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Severe allergic reactions: rash, swelling, anaphylaxis.
  • Clostridium difficile infection: severe colitis presenting with watery diarrhoea.
  • Hepatic enzyme elevation: signs of liver dysfunction.
  • Hypomagnesemia: low magnesium levels causing muscle weakness or arrhythmia.
  • Bone fractures: increased risk with long‑term use.
  • Interstitial nephritis: kidney inflammation presenting with reduced urine output.

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Renal function assessment: adjust use in patients with severe renal impairment.
  • Magnesium monitoring: check serum magnesium during prolonged treatment.
  • Hepatic impairment: use with caution in moderate to severe liver disease.
  • Discontinuation strategy: avoid abrupt cessation in patients with severe GERD to prevent rebound acid hypersecretion.
  • Drug interaction review: evaluate concomitant medications that may affect acid levels or drug metabolism.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Lansoprazole may interact with several medicines; awareness helps prevent reduced efficacy or toxicity.

Major Interactions (Avoid)

  • Atazanavir: decreased absorption leading to sub‑therapeutic antiviral levels.
  • Clopidogrel: reduced conversion to active metabolite, diminishing antiplatelet effect.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible increase in INR, requiring closer coagulation monitoring.
  • Digoxin: higher serum concentrations may occur, necessitating dose adjustment.
  • Ketoconazole: reduced oral absorption due to increased gastric pH.

Frequently Asked Questions

Lansoprazol Flas Stada contains lansoprazole, a proton pump inhibitor indicated for the treatment of gastro‑oesophageal reflux disease, peptic ulcer disease, Helicobacter pylori eradication regimens, and for preventing NSAID‑induced gastric ulcers. It works by reducing gastric acid production, which helps heal and protect the gastrointestinal lining.

Lansoprazole irreversibly inhibits the H+/K+ ATPase enzyme, also known as the gastric proton pump, located on the secretory surface of parietal cells. By blocking this final step of acid secretion, it markedly lowers both basal and stimulated gastric acid output, raising gastric pH and allowing ulcer healing and symptom relief.

The appropriate dose of Lansoprazol Flas Stada is determined by the prescribing healthcare professional based on the specific indication, patient age, renal and hepatic function, and other clinical factors. Patients should follow the prescriber's instructions and not alter the dose without medical advice.

Safety data for lansoprazole in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss the risks and alternatives with their healthcare provider.

To order Lansoprazol Flas Stada, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details, and any necessary import documentation.

Lansoprazole belongs to the same class as omeprazole, pantoprazole, and esomeprazole. All PPIs share a similar mechanism of reducing gastric acid secretion, but they differ in pharmacokinetic profiles, drug‑interaction potential, and dosing frequency. Lansoprazole is often chosen for its rapid onset and favorable tolerability in many patients.

Lansoprazol Flas Stada should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and excessive heat. Keep the product out of reach of children and avoid exposure to direct sunlight. No special refrigeration is required for this oral formulation.

The medication is taken orally, usually as a tablet or capsule, with a glass of water. It can be taken before a meal or as directed by the prescriber; food does not significantly affect its absorption. Swallow the dosage form whole; do not crush, chew, or split unless specifically instructed.

Serious adverse events, though rare, include severe allergic reactions such as anaphylaxis, Clostridium difficile‑associated colitis, liver enzyme elevations, hypomagnesemia, interstitial nephritis, and an increased risk of bone fractures with long‑term use. Patients should seek immediate medical attention if they experience rash, swelling, persistent diarrhoea, or unexplained muscle weakness.

Lansoprazol Flas Stada is contraindicated in individuals with known hypersensitivity to lansoprazole or any component of the formulation. Caution is advised for patients with severe liver disease, those taking medications that require an acidic environment for absorption, and patients with a history of osteoporosis when used long‑term. The prescriber should evaluate suitability before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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