Product image of Lansoprazol Lanzogastro (Lansoprazole) supplied by GNH India

Lansoprazol Lanzogastro

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazol Lanzogastro (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazol Lanzogastro, is a proton pump inhibitor presented as an oral dosage form for oral use. It reduces gastric acid production and is employed in the management of acid‑related gastrointestinal disorders in adult patients, and is indicated for conditions such as gastro‑oesophageal reflux disease, erosive oesophagitis, peptic ulcer disease and Zollinger‑Ellison syndrome.

GNH India supplies Lansoprazol Lanzogastro as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable bulk shipments and adhering to stringent quality standards across all regulated markets.

Manufacturer / TM Owner

Alfasigma Portugal, Lda.

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Indications & Clinical Uses

Lansoprazole acts on the gastric acid secretion pathway and is used to treat several acid‑related gastrointestinal conditions.

  • Gastro‑oesophageal reflux disease (GERD): reduces esophageal acid exposure and promotes symptom relief.
  • Erosive oesophagitis: facilitates healing of erosive lesions in the esophagus.
  • Peptic ulcer disease: supports ulcer healing by decreasing gastric acidity.
  • Helicobacter pylori eradication (in combination therapy): enhances the effectiveness of antibiotic regimens.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid production associated with gastrin‑secreting tumors.

How It Works

  • Lansoprazole selectively and irreversibly inhibits the H+/K+ ATPase enzyme (proton pump) located on the secretory surface of gastric parietal cells. By blocking this final step of acid secretion, it markedly reduces both basal and stimulated gastric acid output, leading to an increased gastric pH and allowing mucosal healing in acid‑related disorders.

Side Effects

Adverse reactions may occur with lansoprazole therapy. Most are mild and transient, but serious events are reported rarely.

Common Side Effects

  • Headache: mild to moderate intensity, often transient.
  • Diarrhea: loose stools that may resolve with continued use.
  • Nausea: occasional feeling of queasiness.
  • Abdominal pain: mild discomfort in the upper abdomen.
  • Flatulence: increased intestinal gas.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis): rash, swelling, difficulty breathing.
  • Clostridioides difficile infection: persistent diarrhea with abdominal cramping.
  • Stevens‑Johnson syndrome/toxic epidermal necrolysis: severe skin reactions.
  • Hepatic enzyme elevation: abnormal liver function tests.
  • Hypomagnesemia: low serum magnesium with prolonged use.
  • Acute pancreatitis: sudden abdominal pain with elevated enzymes.

Precautions & Warnings

Before initiating lansoprazole, consider the following safety measures.

  • Assess renal function: adjust therapy in severe renal impairment.
  • Avoid concomitant use with strong CYP2C19 inhibitors: may increase drug exposure.
  • Monitor for Clostridioides difficile infection: especially in hospitalized patients.
  • Use with caution in the elderly: higher risk of bone fractures.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Lansoprazole can interact with several medicines, altering their effectiveness or safety.

Major Interactions (Avoid)

  • Ketoconazole: reduced absorption of ketoconazole when taken together.
  • Atazanavir: decreased antiviral efficacy of atazanavir.
  • Clopidogrel: diminished antiplatelet effect of clopidogrel.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible increase in INR, requiring closer monitoring.
  • Phenytoin: reduced phenytoin plasma concentrations.
  • Digoxin: potential rise in serum digoxin levels.

Frequently Asked Questions

Lansoprazol Lanzogastro contains lansoprazole, a proton pump inhibitor indicated for the treatment of gastro‑oesophageal reflux disease, erosive oesophagitis, peptic ulcer disease, Helicobacter pylori eradication regimens (when combined with antibiotics) and Zollinger‑Ellison syndrome, all of which involve excessive gastric acid production.

Lansoprazole blocks the H+/K+ ATPase enzyme, also known as the proton pump, on gastric parietal cells. By irreversibly inhibiting this final step of acid secretion, it markedly lowers both basal and stimulated gastric acid output, raising the gastric pH and allowing ulcer and mucosal healing.

The appropriate dose of Lansoprazol Lanzogastro is determined by the prescribing clinician based on the specific indication, patient characteristics and treatment guidelines. Dosage may vary for conditions such as GERD, ulcer disease or Zollinger‑Ellison syndrome, and should follow the prescriber’s instructions.

Safety data for lansoprazole in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare professional after evaluating the individual situation.

To request Lansoprazol Lanzogastro, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Lansoprazol Lanzogastro belongs to the proton pump inhibitor class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, its efficacy and safety profile are similar, though individual patient response and drug‑interaction potential may differ.

Lansoprazol Lanzogastro should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keeping the product in a dry, cool place helps maintain its stability and potency throughout its shelf life.

Lansoprazol Lanzogastro is taken orally, usually as a tablet or capsule, with water. It is generally recommended to swallow the dose whole, preferably before a meal, unless the prescribing information advises otherwise.

Serious risks, though uncommon, include severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated diarrhea, liver enzyme elevations, low magnesium levels with prolonged use, and rare skin reactions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience any of these symptoms.

Lansoprazol Lanzogastro is contraindicated in patients with known hypersensitivity to lansoprazole or any component of the formulation. Caution is also advised for individuals with severe liver disease, those taking certain interacting medications, and patients for whom acid suppression is not indicated.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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