Product image of Lansoprazol Mabo (Lansoprazole) supplied by GNH India

Lansoprazol Mabo

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazol Mabo (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazol Mabo, is a proton pump inhibitor presented as an oral dosage form for oral use. It reduces gastric acid secretion and is indicated for conditions such as gastro‑esophageal reflux disease, erosive esophagitis, peptic ulcer disease, and for use in Helicobacter pylori eradication regimens. GNH India supplies Lansoprazol Mabo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Mabo-Farma, S.A

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Indications & Clinical Uses

Lansoprazol Mabo, a proton pump inhibitor, is employed to manage acid‑related gastrointestinal disorders.

  • Gastro‑esophageal reflux disease (GERD): reduces reflux symptoms and promotes healing of esophageal irritation.
  • Erosive esophagitis: facilitates mucosal repair by decreasing acid exposure.
  • Peptic ulcer disease: supports ulcer healing and prevents recurrence.
  • Helicobacter pylori eradication (in combination therapy): enhances eradication rates by suppressing gastric acidity.
  • Prevention of NSAID‑induced gastric ulcers: lowers risk of ulcer formation in patients using non‑steroidal anti‑inflammatory drugs.

How It Works

  • Lansoprazole irreversibly binds to the H+/K+ ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells. By inhibiting this final step of acid production, it markedly reduces basal and stimulated gastric acid secretion, thereby increasing gastric pH and allowing healing of acid‑related mucosal damage.

Side Effects

Lansoprazol Mabo may cause a range of adverse reactions.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: loose stools occurring intermittently.
  • Nausea: feeling of stomach upset.
  • Abdominal pain: discomfort or cramping in the stomach area.

Serious or Rare Side Effects

  • Severe allergic reactions (anaphylaxis): difficulty breathing, swelling, rash.
  • Clostridium difficile infection: persistent diarrhea with possible colitis.
  • Liver enzyme elevation: signs of hepatic dysfunction.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis: severe skin reactions.

Precautions & Warnings

Before prescribing Lansoprazol Mabo, consider the following safety measures.

  • Renal function assessment: adjust use in patients with severe kidney disease.
  • Hepatic impairment: use with caution in moderate to severe liver dysfunction.
  • Discontinuation: avoid abrupt cessation to prevent rebound acid hypersecretion.
  • Infection monitoring: watch for signs of gastrointestinal infections, especially C. difficile.
  • Drug interaction review: evaluate concomitant medications that may alter acid levels.
  • Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Lansoprazol Mabo can affect the absorption and metabolism of several drugs.

Major Interactions (Avoid)

  • Atazanavir: reduced antiviral efficacy due to decreased gastric acidity.
  • Ketoconazole: impaired antifungal absorption.
  • Nelfinavir: decreased plasma concentrations.
  • Rilpivirine: reduced bioavailability.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential increase in anticoagulant effect.
  • Phenytoin: possible reduction in anticonvulsant levels.
  • Digoxin: altered serum concentrations.
  • Methotrexate: increased risk of toxicity.
  • Clopidogrel: diminished antiplatelet activity.

Frequently Asked Questions

Lansoprazol Mabo is indicated for the treatment of acid‑related gastrointestinal conditions such as gastro‑esophageal reflux disease, erosive esophagitis, and peptic ulcer disease. It is also used as part of combination therapy to eradicate Helicobacter pylori and to prevent gastric ulcers in patients taking non‑steroidal anti‑inflammatory drugs.

Lansoprazole works by irreversibly inhibiting the H+/K+ ATPase enzyme, also known as the gastric proton pump, in the parietal cells of the stomach. This blockade stops the final step of acid secretion, leading to a sustained reduction in gastric acidity and allowing damaged mucosal tissue to heal.

The appropriate dose of Lansoprazol Mabo is determined by the prescribing clinician based on the specific indication, patient age, renal and hepatic function, and other clinical factors. Patients should follow the dosage instructions provided by their healthcare professional and the product label.

Safety data for lansoprazole during pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers will assess individual circumstances before prescribing it to pregnant or nursing women.

To order Lansoprazol Mabo, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials. The team then replies with pricing, availability, shipping details, and any necessary import documentation.

Lansoprazol Mabo belongs to the proton pump inhibitor class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, its efficacy and safety profile are comparable, though individual response and drug‑interaction potential may vary.

Lansoprazol Mabo should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. Keep the product out of reach of children and avoid exposing it to excessive heat or humidity to maintain its stability.

Lansoprazol Mabo is taken orally, usually as a tablet or capsule, with a glass of water. It is generally recommended to swallow the dose whole and not to crush or chew it, unless the product label specifies otherwise.

Serious risks include severe allergic reactions such as anaphylaxis, Clostridium difficile‑associated diarrhea, liver enzyme abnormalities, and rare skin conditions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience symptoms such as rash, difficulty breathing, persistent diarrhea, or jaundice.

Lansoprazol Mabo should be avoided in individuals with known hypersensitivity to lansoprazole or any component of the formulation. Caution is also advised for patients with severe hepatic impairment, those taking medications that require an acidic environment for absorption, and patients with a history of certain serious skin reactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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