Product image of Lansoprazol +pharma (Lansoprazole) supplied by GNH India

Lansoprazol +pharma

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazol +pharma (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazol +pharma, is a proton pump inhibitor presented as an oral dosage form for oral use. It reduces gastric acid secretion and is employed in the management of reflux disease, ulcer conditions and Helicobacter pylori eradication regimens.

GNH India supplies Lansoprazol +pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

+pharma Arzneimittel Gmbh

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Indications & Clinical Uses

Lansoprazole is a proton pump inhibitor used to manage conditions involving excess gastric acid production.

  • Gastroesophageal reflux disease (GERD): alleviates heartburn and esophageal irritation.
  • Peptic ulcer disease: promotes ulcer healing by lowering acid exposure.
  • Erosive esophagitis: reduces mucosal damage and supports tissue repair.
  • Helicobacter pylori eradication regimen: enhances antibiotic effectiveness by suppressing acid.

How It Works

  • Lansoprazole irreversibly binds to the H+/K+ ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells. By inhibiting this final step of acid production, it markedly reduces both basal and stimulated gastric acid secretion, leading to an increased gastric pH and facilitating healing of acid‑related lesions.

Side Effects

Lansoprazole is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: loose stools, usually transient.
  • Nausea: occasional upset stomach.
  • Abdominal pain: cramping or discomfort.
  • Flatulence: increased gas.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, difficulty breathing.
  • Clostridioides difficile infection: persistent diarrhea, abdominal pain.
  • Low magnesium levels: muscle cramps, irregular heartbeat.
  • Bone fractures: increased risk with long‑term use.
  • Liver enzyme elevation: abnormal liver function tests.
  • Acute interstitial nephritis: kidney inflammation, reduced urine output.

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Assess renal function: adjust use in severe impairment.
  • Evaluate hepatic status: use with caution in liver disease.
  • Monitor long‑term use: assess bone health and magnesium levels.
  • Review concomitant medications: potential for drug‑drug interactions.
  • Store at ambient temperature: keep below 25°C, in the original packaging, protected from moisture.

Avoid Interactions

Lansoprazole may affect the plasma concentrations of several co‑administered drugs.

Major Interactions (Avoid)

  • Antiretroviral protease inhibitors (e.g., atazanavir): reduced absorption, may compromise efficacy.
  • Antifungal agents (e.g., ketoconazole, itraconazole): markedly decreased bioavailability.
  • Clopidogrel: reduced activation, diminishing antiplatelet effect.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible increase in INR, monitor coagulation.
  • Methotrexate (high dose): increased serum levels, watch for toxicity.
  • Digoxin: modest increase in serum concentration, consider dose adjustment.

Frequently Asked Questions

Lansoprazol +pharma contains lansoprazole, a proton pump inhibitor indicated for gastroesophageal reflux disease, peptic ulcer disease, erosive esophagitis, and as part of a Helicobacter pylori eradication regimen. It works by lowering stomach acid, helping to relieve symptoms and promote healing in these acid‑related disorders.

Lansoprazole irreversibly inhibits the H+/K+ ATPase enzyme, also known as the gastric proton pump, on the surface of parietal cells. By blocking this final step of acid secretion, it significantly reduces both basal and stimulated gastric acid output, leading to an increased gastric pH and symptom relief.

The specific dose and dosing schedule for Lansoprazol +pharma are determined by the prescribing healthcare professional based on the patient’s condition, severity, and response to therapy. Dosage forms and strengths are selected to match the therapeutic need as directed by the prescriber.

Lansoprazole is classified as Pregnancy Category B, indicating that animal studies have not shown risk to the fetus and there are no adequate human studies. It may be used during pregnancy if clearly needed. Limited data are available for breastfeeding, so the prescriber should weigh potential benefits against possible risks.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Lansoprazole belongs to the proton pump inhibitor class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, its efficacy is similar, but individual patient response and drug‑interaction profiles may differ, influencing the choice of therapy.

Store Lansoprazol +pharma at ambient temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Lansoprazol +pharma is taken orally, usually as a tablet or capsule, with a glass of water. It can be taken with or without food, but consistency in timing relative to meals helps maintain predictable absorption. Follow the prescriber’s instructions regarding frequency and duration.

Serious risks, though uncommon, include severe allergic reactions (anaphylaxis), Clostridioides difficile‑associated diarrhea, low magnesium levels leading to cardiac arrhythmias, and increased risk of bone fractures with long‑term use. Patients should report any unusual symptoms promptly to their healthcare provider.

Lansoprazol +pharma should be avoided in individuals with known hypersensitivity to lansoprazole or other proton pump inhibitors. Caution is advised for patients with severe liver disease, those on medications that have major interactions (e.g., certain antiretrovirals, antifungals, clopidogrel), and patients requiring long‑term therapy without appropriate monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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