Product image of Lansoprazol Stada (Lansoprazole) supplied by GNH India

Lansoprazol Stada

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazol Stada (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazol Stada, is a proton pump inhibitor presented as an oral dosage form for systemic use. It reduces gastric acid production and is used to treat conditions such as gastro‑esophageal reflux disease, peptic ulcer disease and Zollinger‑Ellison syndrome in adults.

GNH India supplies Lansoprazol Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratorio Stada, S.L.

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Indications & Clinical Uses

Lansoprazole is a proton pump inhibitor that reduces gastric acid secretion in several acid‑related disorders.

  • Gastro‑esophageal reflux disease (GERD): alleviates heartburn and esophageal irritation by maintaining higher gastric pH.
  • Peptic ulcer disease: promotes ulcer healing by decreasing acid exposure to the gastric and duodenal mucosa.
  • Helicobacter pylori eradication regimens: used in combination therapy to enhance eradication rates by suppressing acid.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid production associated with gastrin‑secreting tumors.

How It Works

  • Lansoprazole irreversibly binds to the sulfhydryl group of the H+/K+ ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells. By inhibiting this final step of acid secretion, it markedly reduces both basal and stimulated gastric acid output, leading to an increased gastric pH. The inhibition persists until new enzyme molecules are synthesized, providing prolonged acid suppression after each dose.

Side Effects

Lansoprazole may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: loose stools, often transient.
  • Nausea: feeling of stomach upset.
  • Abdominal pain: discomfort in the upper abdomen.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis): rash, swelling, difficulty breathing.
  • Clostridioides difficile infection: persistent diarrhea, abdominal pain.
  • Low magnesium levels (hypomagnesemia): muscle cramps, irregular heartbeat.

Precautions & Warnings

When prescribing lansoprazole, clinicians should consider several safety aspects.

  • Assess renal function: dose adjustment may be needed in severe renal impairment.
  • Monitor for osteoporosis: long‑term therapy may affect calcium absorption.
  • Use with caution in elderly: higher risk of fractures and electrolyte disturbances.
  • Avoid concomitant use with drugs requiring gastric acidity for absorption unless medically indicated.
  • Store at ambient temperature below 25°C: keep in the original container, protect from moisture and light.

Avoid Interactions

Lansoprazole can alter the pharmacokinetics of several medicines.

Major Interactions (Avoid)

  • Ketoconazole or itraconazole: reduced antifungal absorption due to increased gastric pH.
  • Atazanavir: decreased antiviral efficacy from impaired absorption.
  • Clopidogrel: reduced antiplatelet effect due to CYP2C19 inhibition.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible increase in INR, monitor coagulation.
  • Digoxin: altered serum levels, monitor for toxicity.
  • Methotrexate: increased exposure, monitor renal function.

Frequently Asked Questions

Lansoprazol Stada contains the active ingredient lansoprazole, a proton pump inhibitor that reduces gastric acid production. It is used to manage gastro‑esophageal reflux disease, peptic ulcer disease, Helicobacter pylori eradication regimens, and Zollinger‑Ellison syndrome, helping to relieve symptoms and promote healing of acid‑related gastrointestinal conditions.

Lansoprazole works by irreversibly inhibiting the H+/K+ ATPase enzyme, also known as the gastric proton pump, on the secretory surface of parietal cells. This blockade stops the final step of acid secretion, leading to a sustained increase in gastric pH and reduced acidity, which allows damaged mucosa to heal and alleviates acid‑related symptoms.

The appropriate dose of Lansoprazol Stada is determined by the prescribing healthcare professional based on the specific indication, patient characteristics, and clinical response. Dosage forms and strengths may vary, and the prescriber will provide individualized instructions that should be followed precisely.

Safety data for lansoprazole in pregnancy and lactation are limited. The decision to use the medication during pregnancy or while breastfeeding should be made by a qualified healthcare provider after weighing potential benefits against possible risks to the mother and infant.

To request Lansoprazol Stada, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. The sales team will verify trade or institutional credentials and then respond with pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Lansoprazol Stada belongs to the proton pump inhibitor class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, lansoprazole has a similar efficacy profile but may differ in pharmacokinetic properties, drug‑interaction potential, and individual patient tolerance.

Lansoprazol Stada should be stored at ambient temperature below 25 °C. Keep the product in its original packaging, protect it from moisture and direct light, and store it out of reach of children to maintain stability and potency.

Lansoprazol Stada is taken orally, usually as a tablet or capsule, with a glass of water. It is commonly administered before a meal, but patients should follow the specific instructions provided by their prescriber regarding timing and whether it should be taken with or without food.

Serious risks, although uncommon, include severe allergic reactions (anaphylaxis), Clostridioides difficile infection, and electrolyte disturbances such as hypomagnesemia, which can lead to muscle cramps or cardiac arrhythmias. Long‑term use may also increase the risk of bone fractures and vitamin B12 deficiency. Patients should report any unusual symptoms promptly.

Lansoprazol Stada should be avoided in individuals with known hypersensitivity to lansoprazole or any component of the formulation. Caution is also advised for patients with severe liver disease, those taking medications that require an acidic gastric environment for absorption, and patients with a history of osteoporosis or fractures when long‑term therapy is considered.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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