Product image of Lansoprazol Stada (Lansoprazole) supplied by GNH India

Lansoprazol Stada

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazol Stada (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazol Stada, is a proton pump inhibitor presented as an oral tablet for oral use. It reduces gastric acid production and is employed to manage conditions such as gastro‑esophageal reflux disease, duodenal ulcer, Helicobacter pylori eradication regimens, and Zollinger‑Ellison syndrome.

GNH India supplies Lansoprazol Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU GMP standards and provides reliable logistics for bulk and unit‑dose orders across multiple continents.

Manufacturer / TM Owner

Stada Arzneimittel Gmbh

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Indications & Clinical Uses

Lansoprazole, the active component of Lansoprazol Stada, acts on the gastric proton pump to lower acid secretion in several acid‑related disorders.

  • Gastro‑esophageal reflux disease (GERD): reduces reflux symptoms and promotes healing of esophageal irritation.
  • Duodenal ulcer: facilitates ulcer healing by maintaining a less acidic gastric environment.
  • Helicobacter pylori eradication (in combination therapy): enhances the effectiveness of antibiotics by suppressing gastric acid.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid production associated with gastrin‑secreting tumors.

How It Works

  • Lansoprazole irreversibly binds to the H⁺/K⁺‑ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells. By inhibiting this final step of acid secretion, it markedly reduces both basal and stimulated gastric acid output, leading to an increase in gastric pH and allowing mucosal healing. The inhibition is sustained for up to 72 hours, requiring only once‑daily dosing for most indications.

Side Effects

Lansoprazol Stada may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Headache
  • Diarrhea
  • Abdominal pain
  • Nausea

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis)
  • Clostridioides difficile‑associated diarrhea
  • Low serum magnesium (hypomagnesemia)
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis

Precautions & Warnings

When prescribing Lansoprazol Stada, several precautionary measures should be considered to ensure safe use.

  • Renal or hepatic impairment: assess function before initiating therapy and adjust duration as needed.
  • Elderly patients: monitor for increased risk of confusion, falls, and dehydration.
  • Discontinuation: avoid abrupt cessation after prolonged use; taper to reduce rebound acid hypersecretion.
  • Infection risk: be vigilant for signs of gastrointestinal infections, especially C. difficile.
  • Concomitant medications: review drugs that require acidic environment for absorption (e.g., ketoconazole, atazanavir).
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Lansoprazol Stada can alter the pharmacokinetics of several medicines; interactions are classified by clinical significance.

Major Interactions (Avoid)

  • Clarithromycin: may increase lansoprazole levels, raising risk of toxicity.
  • Ketoconazole: reduced absorption of ketoconazole, compromising antifungal efficacy.
  • Atazanavir (and other HIV protease inhibitors): markedly decreased antiviral exposure.
  • Ritonavir‑boosted regimens: significant reduction in protease inhibitor concentrations.

Moderate Interactions (Monitor Closely)

  • Digoxin: increased serum digoxin concentrations; monitor levels.
  • Methotrexate: reduced renal clearance; watch for toxicity.
  • Warfarin: potential enhancement of anticoagulant effect; check INR.
  • Phenytoin: decreased phenytoin levels; adjust dosage if needed.

Frequently Asked Questions

Lansoprazol Stada contains lansoprazole, a proton pump inhibitor that is used to lower stomach acid. It is indicated for the treatment of gastro‑esophageal reflux disease, duodenal ulcers, Helicobacter pylori eradication regimens (in combination with antibiotics), and Zollinger‑Ellison syndrome.

Lansoprazole irreversibly blocks the H⁺/K⁺‑ATPase enzyme, also known as the gastric proton pump, on the surface of parietal cells. By disabling this final step of acid secretion, it reduces both basal and stimulated gastric acid output, raising gastric pH and allowing damaged mucosa to heal.

The appropriate dose of Lansoprazol Stada is determined by the prescribing healthcare professional based on the specific indication, patient age, renal and hepatic function, and treatment duration. Dosage recommendations are provided in the product label and should not be altered without medical advice.

Safety data for lansoprazole in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss treatment options with their physician.

To place an enquiry, visit the product page on gnhindia.com and submit the required quantity using the online form. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Lansoprazol Stada belongs to the proton pump inhibitor class, which generally provides more potent and longer‑lasting acid suppression than H₂‑receptor antagonists such as ranitidine. Compared with other PPIs like omeprazole, lansoprazole has a similar efficacy profile, but individual patient response and drug‑interaction potential may differ, influencing the choice of therapy.

Store Lansoprazol Stada at ambient temperature, preferably below 25 °C. Keep the tablets in the original blister pack or container, protect them from moisture, heat and direct sunlight, and ensure the package is tightly closed when not in use.

Lansoprazol Stada is taken orally, usually as a whole tablet swallowed with a glass of water. It may be taken with or without food, but consistency in relation to meals is recommended. The tablet should not be crushed, chewed, or split unless specifically instructed by a healthcare professional.

Serious adverse events, although rare, include severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, significant low magnesium levels (hypomagnesemia), and severe skin reactions like Stevens‑Johnson syndrome or toxic epidermal necrolysis. Patients should seek immediate medical attention if they experience rash, persistent diarrhea, muscle cramps, or signs of an allergic reaction.

Lansoprazol Stada should be avoided in individuals with a known hypersensitivity to lansoprazole or any component of the formulation. Caution is also advised for patients with severe liver disease, those taking medications that require an acidic gastric environment for absorption, and patients who have experienced previous severe adverse reactions to proton pump inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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