Product image of Lansoprazol Zentiva (Lansoprazole) supplied by GNH India

Lansoprazol Zentiva

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazol Zentiva (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazol Zentiva, is a proton pump inhibitor presented as an oral dosage form for oral use. It reduces gastric acid secretion and is used to treat acid‑related disorders such as gastro‑oesophageal reflux disease, erosive esophagitis, peptic ulcer disease and Zollinger‑Ellison syndrome.

GNH India supplies Lansoprazol Zentiva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, transplant centres and clinics worldwide.

Manufacturer / TM Owner

Zentiva Portugal, Lda

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lansoprazole is indicated for several acid‑related conditions, acting to suppress gastric acid production.

  • Gastro‑oesophageal reflux disease (GERD): reduces esophageal acid exposure and promotes healing of mucosal injury.
  • Erosive esophagitis: facilitates ulcer healing by maintaining a higher gastric pH.
  • Peptic ulcer disease: supports ulcer resolution by decreasing gastric acidity.
  • Helicobacter pylori eradication regimens: enhances the effectiveness of antibiotic combinations by creating a less acidic environment.
  • Zollinger‑Ellison syndrome: controls hyper‑secretion of gastric acid in this rare neuroendocrine tumor.

How It Works

  • Lansoprazole selectively and irreversibly inhibits the H⁺/K⁺‑ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells. By blocking this final step of acid secretion, it markedly reduces basal and stimulated gastric acid output, leading to an increased gastric pH.

Side Effects

Lansoprazole may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Headache: mild, transient headache.
  • Diarrhea: loose stools, usually self‑limiting.
  • Nausea: occasional feeling of queasiness.
  • Abdominal pain: mild discomfort in the stomach area.
  • Flatulence: increased gas production.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Severe allergic reactions: rash, swelling, difficulty breathing.
  • Clostridioides difficile infection: severe colitis with diarrhea.
  • Liver enzyme elevation: signs of hepatic injury.
  • Low magnesium levels: muscle cramps, irregular heartbeat.
  • Stevens‑Johnson syndrome: serious skin blistering.
  • Interstitial nephritis: kidney inflammation.

Precautions & Warnings

Before prescribing Lansoprazole, consider the following precautions to ensure safe use.

  • Assess renal function: adjust therapy in patients with severe renal impairment.
  • Monitor magnesium levels: prolonged treatment may cause hypomagnesemia.
  • Review concomitant medications: avoid use with drugs that have major interactions.
  • Use with caution in the elderly: increased risk of fractures and infections.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Lansoprazole can affect the pharmacokinetics of several medicines; awareness of these interactions helps prevent therapeutic failures or toxicity.

Major Interactions (Avoid)

  • Ketoconazole: reduced absorption and efficacy of ketoconazole.
  • Atazanavir: decreased plasma concentrations of atazanavir.
  • Clopidogrel: diminished activation leading to reduced antiplatelet effect.
  • Warfarin: possible increase in INR and bleeding risk.

Moderate Interactions (Monitor Closely)

  • Digoxin: may raise serum digoxin levels.
  • Methotrexate: increased risk of toxicity with high‑dose regimens.
  • Phenytoin: decreased phenytoin concentrations.

Frequently Asked Questions

Lansoprazol Zentiva contains the proton pump inhibitor lansoprazole and is prescribed to manage conditions that involve excess stomach acid. It is commonly used for gastro‑oesophageal reflux disease, erosive esophagitis, peptic ulcer disease, Helicobacter pylori eradication regimens, and Zollinger‑Ellison syndrome.

Lansoprazole works by binding irreversibly to the H⁺/K⁺‑ATPase enzyme, also known as the gastric proton pump, on the surface of parietal cells. This blocks the final step of acid secretion, resulting in a sustained reduction of gastric acidity and an elevated stomach pH.

The appropriate dose of Lansoprazol Zentiva is determined by the prescribing clinician based on the specific condition, severity, and patient characteristics. Dosage may vary for short‑term ulcer healing versus long‑term management of chronic acid‑related disorders.

Safety data for lansoprazole in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lansoprazole belongs to the same class as omeprazole, esomeprazole, pantoprazole and rabeprazole. All share a similar mechanism of inhibiting the gastric proton pump, but they differ slightly in pharmacokinetic profiles, drug‑interaction potential and dosing convenience. Choice of agent often depends on physician preference, patient response and specific interaction considerations.

Lansoprazol Zentiva should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in humid or excessively hot environments.

The medication is taken orally, usually as a whole tablet swallowed with a glass of water. It is generally recommended to take the dose before a meal, but patients should follow the specific instructions provided by their prescriber.

Serious adverse events, although rare, include severe allergic reactions such as rash or swelling, Clostridioides difficile‑associated colitis, liver enzyme elevations, low magnesium levels, Stevens‑Johnson syndrome and interstitial nephritis. Patients should seek immediate medical attention if they experience any of these symptoms.

Individuals with known hypersensitivity to lansoprazole or any component of the formulation should avoid the product. Caution is also advised for patients with severe liver disease, those taking medications with major interactions, and patients for whom alternative therapies are more appropriate as determined by their healthcare provider.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Lansoprazole

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT