Product image of Lansoprazole supplied by GNH India

Lansoprazole

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazole

Lansoprazole, the active ingredient in Lansoprazole, is a proton pump inhibitor presented as an oral tablet for oral use. It treats acid‑related disorders such as gastro‑esophageal reflux disease, peptic ulcer disease and erosive esophagitis in adult patients.

GNH India supplies Lansoprazole as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Krka, D.D., Novo Mesto

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lansoprazole is used to manage conditions associated with excess gastric acid secretion.

  • Gastro‑esophageal reflux disease (GERD): reduces reflux symptoms and promotes healing of esophageal irritation.
  • Peptic ulcer disease: facilitates ulcer healing and helps prevent recurrence.
  • Erosive esophagitis: heals erosive lesions and reduces further damage.
  • Helicobacter pylori eradication (as part of combination therapy): enhances eradication rates when combined with appropriate antibiotics.

How It Works

  • Lansoprazole selectively inhibits the H+/K+ ATPase enzyme (the gastric proton pump) located in the secretory canaliculi of gastric parietal cells. By blocking this final step of acid production, it markedly reduces gastric acid secretion, leading to an increase in gastric pH and providing a conducive environment for mucosal healing.

Side Effects

Adverse reactions to lansoprazole vary in frequency and severity.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: watery stools, usually transient.
  • Nausea: occasional feeling of queasiness.
  • Abdominal pain: mild discomfort in the stomach area.
  • Flatulence: increased intestinal gas.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Severe allergic reactions (anaphylaxis): rash, swelling, difficulty breathing.
  • Clostridioides difficile infection: severe colitis presenting with diarrhea.
  • Hypomagnesemia: low magnesium levels with prolonged use.
  • Stevens‑Johnson syndrome: severe skin and mucous membrane reactions.
  • Interstitial nephritis: inflammation of kidney tissue.
  • Elevated liver enzymes: signs of hepatic stress.

Precautions & Warnings

Before initiating lansoprazole therapy, consider the following precautions.

  • Assess renal function: adjust use in patients with severe renal impairment.
  • Monitor magnesium levels: prolonged therapy may lead to hypomagnesemia.
  • Use cautiously in liver disease: monitor hepatic function tests.
  • Evaluate bleeding risk: gastric acid suppression can affect platelet function.
  • Pregnancy and lactation: prescribe only if potential benefit justifies potential risk.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Lansoprazole may alter the pharmacokinetics of several co‑administered drugs.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet effect, increasing cardiovascular risk.
  • Atorvastatin: increased plasma concentration, raising risk of myopathy.
  • Methotrexate: elevated serum levels, potentially causing toxicity.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible increase in INR, requiring closer anticoagulation monitoring.
  • Digoxin: may raise serum digoxin concentrations, necessitating dose adjustment.

Frequently Asked Questions

Lansoprazole is prescribed for acid‑related gastrointestinal disorders. It is effective in managing gastro‑esophageal reflux disease (GERD), promoting healing of peptic ulcers, and treating erosive esophagitis. It is also used as part of combination therapy to eradicate Helicobacter pylori infection when paired with appropriate antibiotics.

Lansoprazole works by selectively inhibiting the H+/K+ ATPase enzyme, commonly known as the gastric proton pump, located in the parietal cells of the stomach lining. This inhibition blocks the final step of acid secretion, leading to a sustained increase in gastric pH and providing an environment that supports mucosal healing.

The dosing regimen for Lansoprazole is individualized by the prescribing healthcare professional based on the specific indication, severity of disease, and patient characteristics. The prescriber determines the appropriate dose, frequency, and duration of therapy, and patients should follow the instructions provided on the prescription label.

The safety of Lansoprazole in pregnancy and lactation has not been definitively established. It should be used only when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers will assess the risk‑benefit profile before prescribing it to pregnant or nursing women.

To order Lansoprazole, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details and any necessary import documentation.

Lansoprazole belongs to the same class as omeprazole, esomeprazole, pantoprazole and rabeprazole. All share the same mechanism of inhibiting the gastric proton pump, but they differ slightly in pharmacokinetic profiles, potency, and drug‑interaction potential. Clinical efficacy is comparable; selection often depends on physician preference, patient response, and specific interaction considerations.

Lansoprazole tablets should be stored at ambient temperature, typically below 25 °C (77 °F). Keep the product in its original packaging, protect it from moisture and direct light, and store it out of reach of children to maintain stability and potency.

Lansoprazole is administered orally. The tablet should be swallowed whole with a glass of water, preferably before a meal, although it can be taken with or without food as directed by the prescriber. Patients should not crush, chew, or split the tablet unless specifically instructed.

Serious risks include severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, low magnesium levels (hypomagnesemia) with prolonged use, Stevens‑Johnson syndrome, interstitial nephritis, and significant elevations in liver enzymes. Patients should seek immediate medical attention if they experience rash, persistent diarrhea, muscle weakness, or signs of liver dysfunction.

Lansoprazole should be avoided in individuals with known hypersensitivity to the drug or any component of the formulation. Caution is advised for patients with severe liver disease, those taking medications that may interact significantly, and for pregnant or breastfeeding women unless the benefit justifies the potential risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.