Product image of Lansoprazole Arrow (Lansoprazole) supplied by GNH India

Lansoprazole Arrow

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazole Arrow (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazole Arrow, is a proton pump inhibitor presented as an oral dosage form for systemic use. It reduces gastric acid production and is used to treat conditions such as gastro‑esophageal reflux disease, peptic ulcer disease, and related acid‑related disorders in adult patients.

GNH India supplies Lansoprazole Arrow as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution, including temperature‑controlled shipping where required.

Manufacturer / TM Owner

Arrow Generiques

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Indications & Clinical Uses

Lansoprazole is a proton pump inhibitor indicated for several acid‑related gastrointestinal conditions.

  • Gastro‑esophageal reflux disease (GERD): relieves heartburn and promotes healing of esophageal erosion.
  • Peptic ulcer disease: accelerates ulcer healing and reduces recurrence.
  • Helicobacter pylori eradication: used as part of combination therapy to eliminate H. pylori infection.
  • Erosive esophagitis: speeds mucosal healing and prevents relapse.
  • Zollinger‑Ellison syndrome: controls gastric acid hypersecretion in this rare endocrine disorder.

How It Works

  • Lansoprazole selectively and irreversibly inhibits the H+/K+ ATPase enzyme, commonly known as the gastric proton pump, located on the secretory surface of gastric parietal cells. By blocking this final step of acid production, it markedly reduces both basal and stimulated gastric acid secretion, leading to an increase in gastric pH and providing an environment conducive to ulcer healing and symptom relief.

Side Effects

Lansoprazole may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Headache: mild to moderate pain may occur.
  • Diarrhea: loose stools are reported.
  • Abdominal pain: discomfort in the stomach area.
  • Nausea: feeling of sickness.

Serious or Rare Side Effects

  • Clostridioides difficile infection: severe colitis may develop.
  • Severe allergic reaction (anaphylaxis): rash, swelling, breathing difficulty.
  • Low magnesium (hypomagnesemia): muscle cramps, irregular heartbeat.

Precautions & Warnings

Before prescribing Lansoprazole, clinicians should consider several safety aspects.

  • Assess renal function: dose adjustment may be needed in severe impairment.
  • Monitor for infection: prolonged use can increase risk of gastrointestinal infections.
  • Use cautiously in elderly: higher incidence of fractures reported.
  • Avoid abrupt discontinuation: may cause rebound acid hypersecretion.
  • Consider drug interactions: review concomitant medications for potential effects.
  • Store at ambient temperature: keep below 25 °C, in the original container, protected from moisture and light.

Avoid Interactions

Lansoprazole can affect the pharmacokinetics of several medicines, requiring attention to interaction risk.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet activation.
  • Atazanavir: decreased absorption and antiviral efficacy.
  • Methotrexate (high dose): increased toxicity due to reduced renal clearance.

Moderate Interactions (Monitor Closely)

  • Warfarin: variable INR, monitor coagulation.
  • Diazepam: increased plasma levels, watch for sedation.
  • Digoxin: altered absorption, check serum concentrations.

Frequently Asked Questions

Lansoprazole Arrow contains the proton pump inhibitor lansoprazole and is used to treat acid‑related gastrointestinal disorders such as gastro‑esophageal reflux disease, peptic ulcer disease, erosive esophagitis, Helicobacter pylori infection (as part of combination therapy), and the rare Zollinger‑Ellison syndrome.

Lansoprazole works by selectively and irreversibly blocking the H+/K+ ATPase enzyme, also known as the gastric proton pump, in the secretory membrane of parietal cells. This inhibition stops the final step of gastric acid production, leading to a sustained increase in stomach pH and reduction of acid‑related damage.

The appropriate dose of Lansoprazole Arrow is determined by the prescribing healthcare professional based on the specific indication, patient characteristics, and clinical response. Dosage regimens may vary, and patients should follow the prescriber’s instructions without self‑adjusting the dose.

Safety data for lansoprazole in pregnancy and lactation are limited. The drug should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers will evaluate individual circumstances before prescribing during pregnancy or while breastfeeding.

To order Lansoprazole Arrow, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. The sales team then replies with pricing, availability, shipping details (including any temperature‑controlled requirements) and the necessary import documentation.

Lansoprazole belongs to the same class as omeprazole, esomeprazole and pantoprazole. All PPIs share a similar mechanism of inhibiting the gastric proton pump, but they differ slightly in pharmacokinetic profiles, onset of action and drug‑interaction potential. Lansoprazole is often chosen for its once‑daily dosing and a well‑established safety record, while individual patient response may guide the selection of a specific PPI.

Lansoprazole Arrow should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct light, and ensure the container is tightly closed when not in use. Do not store in a refrigerator or freezer.

Lansoprazole Arrow is taken orally, usually with a glass of water. It can be taken with or without food, but consistent timing each day helps maintain steady drug levels. Patients should swallow the tablet whole and avoid crushing or chewing unless the prescriber advises otherwise.

Serious risks, although uncommon, include Clostridioides difficile‑associated colitis, severe allergic reactions such as anaphylaxis, and electrolyte disturbances like hypomagnesemia, which can cause muscle cramps or cardiac arrhythmias. Long‑term use may also be linked to increased risk of bone fractures and vitamin B12 deficiency, so monitoring is advised for prolonged therapy.

Lansoprazole Arrow should be avoided in patients with known hypersensitivity to lansoprazole or any component of the formulation. Caution is also warranted for individuals with severe liver impairment, those taking medications that require an acidic environment for absorption, and patients with a history of unexplained low magnesium levels. The prescriber will assess suitability on a case‑by‑case basis.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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