Product image of Lansoprazole Arrow Lab (Lansoprazole) supplied by GNH India

Lansoprazole Arrow Lab

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazole Arrow Lab (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazole Arrow Lab, is a proton pump inhibitor presented as a tablet for oral use. It reduces gastric acid secretion and is used to manage acid‑related disorders such as gastro‑esophageal reflux disease and peptic ulcer disease in adult patients.

GNH India supplies Lansoprazole Arrow Lab as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution, including temperature‑controlled shipping where required.

Manufacturer / TM Owner

Arrow Generiques

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Indications & Clinical Uses

Lansoprazole is a proton pump inhibitor that reduces gastric acid production, and it is indicated for several acid‑related gastrointestinal conditions.

  • Gastro‑esophageal reflux disease (GERD): provides symptomatic relief and promotes healing of esophageal erosion.
  • Peptic ulcer disease: facilitates ulcer healing and reduces recurrence risk.
  • Helicobacter pylori eradication regimens: used in combination therapy to increase eradication rates.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid secretion associated with gastrin‑producing tumors.

How It Works

  • Lansoprazole irreversibly binds to the H+/K+ ATPase enzyme (the gastric proton pump) on the secretory surface of parietal cells. By inhibiting this final step of acid secretion, it markedly reduces both basal and stimulated gastric acid output, leading to increased gastric pH. The inhibition is dose‑dependent and persists until new proton pumps are synthesized, which may take up to several days, allowing sustained acid suppression with once‑daily dosing.

Side Effects

Lansoprazole may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Headache: mild to moderate pain often resolving without intervention.
  • Diarrhea: loose stools that may improve with continued therapy.
  • Nausea: feeling of stomach upset, usually transient.
  • Abdominal pain: discomfort in the stomach area.
  • Flatulence: increased intestinal gas.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Severe allergic reactions (anaphylaxis, angioedema): require immediate medical attention.
  • Clostridioides difficile infection: may cause severe colitis.
  • Hypomagnesemia: low magnesium levels with prolonged use.
  • Bone fractures: increased risk with long‑term therapy.
  • Interstitial nephritis: inflammation of kidney tissue.
  • Hepatic injury: rare liver function abnormalities.

Precautions & Warnings

Before prescribing Lansoprazole, clinicians should consider several precautionary measures to ensure safe use.

  • Assess renal and hepatic function: adjust use in severe impairment.
  • Evaluate for history of hypersensitivity: avoid if allergic to PPIs.
  • Monitor long‑term therapy: assess need for continued treatment after 8‑12 weeks.
  • Check for concomitant use of drugs requiring gastric pH alteration: may affect absorption.
  • Pregnancy and lactation: use only if benefit outweighs risk.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Lansoprazole can alter the pharmacokinetics of several medicines, requiring attention to potential interactions.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet effect.
  • Atazanavir: decreased absorption and efficacy.
  • High‑dose methotrexate: increased toxicity risk.

Moderate Interactions (Monitor Closely)

  • Warfarin: may enhance anticoagulant effect, requiring INR monitoring.
  • Digoxin: increased serum levels, risk of toxicity.
  • Diazepam: heightened sedation, monitor CNS effects.

Frequently Asked Questions

Lansoprazole Arrow Lab is a proton pump inhibitor indicated for the treatment of acid‑related gastrointestinal conditions such as gastro‑esophageal reflux disease, peptic ulcer disease, Helicobacter pylori eradication regimens, and Zollinger‑Ellison syndrome. It works by reducing gastric acid secretion, helping to relieve symptoms and promote healing of the gastrointestinal mucosa.

Lansoprazole irreversibly inhibits the H+/K+ ATPase enzyme, also known as the gastric proton pump, located on the secretory surface of parietal cells. By blocking this final step of acid production, it markedly lowers both basal and stimulated gastric acid output, resulting in an increased gastric pH and reduced acidity in the stomach.

The specific dose of Lansoprazole Arrow Lab is determined by the prescribing healthcare professional based on the patient’s condition, severity, and response to therapy. Typical adult regimens range from once‑daily to twice‑daily dosing, but the exact strength and frequency should follow the prescriber’s instructions and local labeling.

Safety data for Lansoprazole during pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers should evaluate each case individually and discuss potential risks and alternatives with the patient.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity of Lansoprazole Arrow Lab. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Lansoprazole belongs to the same class as omeprazole, esomeprazole, pantoprazole and rabeprazole. All share a common mechanism of inhibiting the gastric proton pump, but they differ slightly in pharmacokinetic profiles, potency and drug‑interaction potential. Lansoprazole is often chosen for its once‑daily dosing convenience and a well‑established safety record.

Lansoprazole Arrow Lab should be stored at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct light, and ensure the container is tightly closed to maintain stability throughout its shelf life.

The medication is administered orally. Patients should swallow the tablet whole with a glass of water, and it may be taken with or without food. If a dose is missed, it should be taken as soon as remembered unless the next scheduled dose is near, in which case the missed dose should be skipped.

Serious risks include severe allergic reactions such as anaphylaxis or angioedema, Clostridioides difficile‑associated colitis, low magnesium levels (hypomagnesemia) with prolonged use, increased risk of bone fractures, interstitial nephritis, and rare cases of hepatic injury. Patients should seek immediate medical attention if any of these symptoms occur.

Lansoprazole Arrow Lab is contraindicated in individuals with a known hypersensitivity to lansoprazole, other proton pump inhibitors, or any component of the formulation. Caution is also advised for patients with severe liver disease, and it should be avoided in those taking medications that require an acidic gastric environment for absorption unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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