Product image of Lansoprazole Aurobindo (Lansoprazole) supplied by GNH India

Lansoprazole Aurobindo

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazole Aurobindo (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazole Aurobindo, is a proton pump inhibitor presented as a dosage form for oral use. It reduces gastric acid production and is employed in the management of acid‑related gastrointestinal conditions in adults.
GNH India supplies Lansoprazole Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aurobindo Pharma B.V.

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Indications & Clinical Uses

Lansoprazole acts on the gastric acid secretion pathway and is indicated for several acid‑related disorders.

  • Gastroesophageal reflux disease (GERD): reduces acid exposure and relieves heartburn and regurgitation symptoms.
  • Erosive esophagitis: promotes healing of inflamed esophageal tissue by lowering gastric acidity.
  • Peptic ulcer disease: facilitates ulcer healing and prevents recurrence by suppressing acid secretion.
  • Helicobacter pylori eradication: used in combination regimens to improve bacterial clearance.

How It Works

  • Lansoprazole selectively and irreversibly inhibits the H+/K+ ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells. By blocking this final step of acid production, it markedly decreases both basal and stimulated gastric acid secretion, leading to an increase in gastric pH and providing a therapeutic environment for ulcer healing and symptom relief.

Side Effects

Adverse reactions may occur with Lansoprazole use.

Common Side Effects

  • Headache: mild to moderate pain often transient.
  • Diarrhea: loose stools that may resolve with continued therapy.
  • Nausea: feeling of queasiness, usually mild.
  • Abdominal pain: discomfort in the stomach region.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or difficulty breathing requiring immediate medical attention.
  • Low magnesium levels: may cause muscle cramps, irregular heartbeat, or seizures.
  • Clostridioides difficile infection: severe colitis presenting with watery diarrhea and abdominal pain.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess renal function: adjust use in patients with significant impairment.
  • Monitor magnesium levels: especially during prolonged treatment.
  • Evaluate for Helicobacter pylori infection: confirm eradication after therapy.
  • Use with caution in elderly patients: increased risk of fractures and renal issues.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Lansoprazole may alter the plasma concentrations of several co‑administered drugs.

Major Interactions (Avoid)

  • Ketoconazole: reduced antifungal absorption.
  • Atazanavir: decreased antiviral efficacy.
  • Clarithromycin: increased risk of cardiac arrhythmias.

Moderate Interactions (Monitor Closely)

  • Clopidogrel: diminished antiplatelet effect.
  • Digoxin: potential increase in serum levels.
  • Methotrexate: enhanced toxicity, especially at high doses.

Frequently Asked Questions

Lansoprazole Aurobindo is prescribed to treat gastroesophageal reflux disease (GERD), erosive esophagitis, peptic ulcer disease, and to support Helicobacter pylori eradication regimens. By lowering stomach acidity, it helps relieve symptoms, promotes ulcer healing, and enhances the effectiveness of antibiotic combinations used against H. pylori.

Lansoprazole belongs to the proton pump inhibitor class. It binds irreversibly to the H+/K+ ATPase enzyme, also known as the gastric proton pump, on the surface of parietal cells. This binding blocks the final step of acid secretion, leading to a sustained increase in gastric pH and reduced acidity.

The specific dose and treatment duration are determined by the prescribing clinician based on the patient’s diagnosis, severity of disease, and individual response. Healthcare professionals tailor the regimen to achieve optimal acid control while minimizing potential risks.

Safety data for Lansoprazole in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss the medication with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Lansoprazole, like other proton pump inhibitors (e.g., omeprazole, esomeprazole), provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with some PPIs, Lansoprazole has a similar efficacy profile but may differ slightly in metabolism pathways, which can influence drug‑interaction potential.

Store the product at room temperature, preferably below 25 °C, in its original packaging. Protect it from excess moisture and direct sunlight. Do not refrigerate or freeze unless the label specifically indicates otherwise.

Lansoprazole Aurobindo is taken orally, usually as a whole tablet or capsule. It should be swallowed with a glass of water, preferably before a meal, unless the prescribing information advises otherwise.

Serious adverse events, though uncommon, include severe allergic reactions (anaphylaxis), significant low magnesium levels that can cause muscle weakness or cardiac arrhythmias, and Clostridioides difficile‑associated colitis. Patients should seek immediate medical attention if they experience symptoms such as rash, swelling, persistent diarrhea, or muscle cramps.

Individuals with a known hypersensitivity to lansoprazole or any component of the formulation should avoid the product. Caution is also advised for patients with severe liver disease, as metabolism may be impaired. The prescribing clinician will evaluate contraindications before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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