Product image of Lansoprazole Crescent Pharma (Lansoprazole) supplied by GNH India

Lansoprazole Crescent Pharma

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazole Crescent Pharma (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazole Crescent Pharma, is a proton pump inhibitor presented as an oral tablet for oral use. It reduces gastric acid production and is used to treat conditions such as gastro‑esophageal reflux disease, peptic ulcer disease, and Helicobacter pylori infection in adult patients.

GNH India supplies Lansoprazole Crescent Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product meets EU quality standards and is distributed under strict regulatory compliance.

Manufacturer / TM Owner

Crescent Pharma Limited

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Indications & Clinical Uses

Lansoprazole is a proton pump inhibitor used to manage acid‑related gastrointestinal disorders.

  • Gastro‑esophageal reflux disease (GERD): reduces acid exposure and promotes healing of esophageal irritation.
  • Peptic ulcer disease: facilitates ulcer healing by suppressing gastric acid secretion.
  • Helicobacter pylori eradication: enhances the effectiveness of combination antibiotic regimens.
  • Erosive esophagitis: promotes mucosal recovery by maintaining a higher gastric pH.

How It Works

  • Lansoprazole selectively and irreversibly inhibits the H+/K+ ATPase (proton pump) located on the secretory surface of gastric parietal cells. By blocking this final step of acid production, it markedly lowers gastric acidity, allowing damaged mucosa to heal and reducing reflux‑related symptoms. The inhibition persists until new pumps are synthesized, providing prolonged acid suppression after a single dose.

Side Effects

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: watery stools, usually transient.
  • Abdominal pain: cramping or discomfort.
  • Nausea: feeling of queasiness.
  • Flatulence: increased gas.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction with rash, swelling, and breathing difficulty.
  • Clostridioides difficile infection: severe colitis presenting with watery diarrhea.
  • Stevens‑Johnson syndrome: skin blistering and mucosal involvement.
  • Elevated liver enzymes: indication of hepatic stress.
  • Hypomagnesemia: low magnesium levels causing muscle cramps.
  • Acute pancreatitis: abdominal pain radiating to the back.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess renal function: adjust use in severe impairment.
  • Review concomitant medications: avoid known contraindicated drugs.
  • Monitor for infection signs: especially if prolonged use is planned.
  • Use cautiously in elderly patients: increased sensitivity to adverse effects.
  • Discuss pregnancy and lactation: evaluate risk‑benefit with prescriber.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Lansoprazole can alter the pharmacokinetics of several drugs; interaction severity varies.

Major Interactions (Avoid)

  • Ketoconazole: reduced absorption and efficacy.
  • Atazanavir: decreased plasma concentrations.
  • Clopidogrel: impaired activation leading to reduced antiplatelet effect.
  • Warfarin: potential increase in INR and bleeding risk.

Moderate Interactions (Monitor Closely)

  • Digoxin: increased serum levels, monitor cardiac function.
  • Methotrexate: higher toxicity risk, especially at high doses.
  • Phenytoin: decreased levels, may require dosage adjustment.

Frequently Asked Questions

Lansoprazole Crescent Pharma is prescribed to treat acid‑related gastrointestinal disorders such as gastro‑esophageal reflux disease, peptic ulcer disease, erosive esophagitis, and to support Helicobacter pylori eradication regimens. It works by lowering stomach acid, which helps heal damaged tissue and reduces symptoms like heartburn and ulcer pain.

Lansoprazole blocks the H+/K+ ATPase enzyme, also known as the proton pump, on gastric parietal cells. This enzyme is the final step in the secretion of gastric acid. By irreversibly inhibiting the pump, lansoprazole markedly reduces acid production, allowing the gastrointestinal lining to heal and decreasing reflux symptoms.

The specific dose and dosing schedule for Lansoprazole Crescent Pharma are determined by the prescribing clinician based on the patient’s condition, severity, and response to therapy. Healthcare professionals tailor the regimen to each individual, and patients should follow the prescriber’s instructions without deviation.

Safety data for Lansoprazole Crescent Pharma in pregnancy and lactation are limited. The prescriber should evaluate the potential benefits against any possible risks to the fetus or infant. If treatment is deemed necessary, it should be used under medical supervision, and breastfeeding mothers should discuss any concerns with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials. After verification, the sales team provides pricing, availability, shipping details (including any cold‑chain needs), and assists with import documentation.

Lansoprazole belongs to the proton pump inhibitor (PPI) class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, lansoprazole has a similar efficacy profile but may differ slightly in metabolism and drug‑interaction potential, making individual patient factors important when selecting therapy.

Lansoprazole Crescent Pharma should be stored at room temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability throughout its shelf life.

Lansoprazole Crescent Pharma is taken orally, usually as a whole tablet swallowed with water. It is generally recommended to take the dose before a meal, often in the morning, unless the prescriber advises otherwise. Patients should not crush, chew, or split the tablet unless instructed.

Serious risks, though uncommon, include severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, Stevens‑Johnson syndrome, and significant electrolyte disturbances like low magnesium. Patients should seek immediate medical attention if they experience symptoms such as rash, swelling, persistent diarrhea, muscle cramps, or unexplained fatigue.

Lansoprazole Crescent Pharma is contraindicated in individuals with known hypersensitivity to lansoprazole or any component of the formulation. Patients with severe liver disease, those taking medications that require an acidic environment for absorption, or those with a history of certain allergic reactions should discuss alternatives with their healthcare provider.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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