Product image of Lansoprazole Eg (Lansoprazole) supplied by GNH India

Lansoprazole Eg

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazole Eg (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazole EG, is a proton pump inhibitor presented as an oral dosage form for oral use. It reduces gastric acid production and is used to treat conditions such as gastro‑oesophageal reflux disease and peptic ulcer disease in adults.
GNH India supplies Lansoprazole EG as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eurogenerics N.V./S.A.

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Indications & Clinical Uses

Lansoprazole is a proton pump inhibitor that acts on the gastric acid secretion pathway, providing relief in several acid‑related disorders.

  • Gastro‑oesophageal reflux disease (GERD): alleviates heartburn and esophageal irritation by lowering stomach acidity.
  • Peptic ulcer disease: promotes ulcer healing by reducing acid exposure to the gastric mucosa.
  • Helicobacter pylori eradication: used in combination regimens to increase eradication rates.
  • Erosive esophagitis: heals inflamed esophageal tissue by maintaining a less acidic environment.

How It Works

  • Lansoprazole selectively and irreversibly inhibits the H+/K+ ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells. By blocking this final step of acid secretion, it markedly reduces both basal and stimulated gastric acid output, allowing mucosal healing and symptom relief in acid‑related gastrointestinal conditions.

Side Effects

Lansoprazole is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: loose stools, usually transient.
  • Nausea: occasional feeling of queasiness.
  • Abdominal pain: mild discomfort in the stomach area.
  • Flatulence: increased intestinal gas.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Clostridioides difficile infection: persistent watery diarrhea.
  • Low magnesium levels: muscle cramps, irregular heartbeat.
  • Bone fractures: increased risk with long‑term use.
  • Liver enzyme elevation: abnormal liver function tests.
  • Acute interstitial nephritis: kidney inflammation presenting with fever and rash.

Precautions & Warnings

Before initiating therapy with Lansoprazole, consider the following safety measures.

  • Assess renal function: adjust use in severe kidney impairment.
  • Evaluate hepatic status: use cautiously in liver disease.
  • Review long‑term use: monitor for osteoporosis or fractures.
  • Check for infections: be alert to signs of C. difficile colitis.
  • Pregnancy and lactation: discuss risks with a healthcare professional.
  • Store at ambient temperature: keep below 25°C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Lansoprazole may alter the plasma concentrations of several co‑administered drugs.

Major Interactions (Avoid)

  • Antifungal agents (e.g., ketoconazole, itraconazole): reduced absorption and efficacy.
  • HIV protease inhibitors (e.g., atazanavir): markedly decreased plasma levels.
  • Clopidogrel: diminished antiplatelet effect.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential increase in INR, monitor coagulation.
  • Digoxin: possible increase in serum concentration.
  • Methotrexate (high dose): reduced clearance, monitor toxicity.
  • Diazepam: increased sedation, observe clinical response.

Frequently Asked Questions

Lansoprazole EG is used to treat acid‑related gastrointestinal disorders such as gastro‑oesophageal reflux disease, peptic ulcer disease, erosive esophagitis, and as part of combination therapy for Helicobacter pylori eradication. By lowering stomach acidity, it helps relieve symptoms and promotes healing of the affected mucosa.

Lansoprazole works by irreversibly binding to the H+/K+ ATPase enzyme, also known as the gastric proton pump, on the surface of parietal cells. This inhibition blocks the final step of gastric acid secretion, leading to a sustained reduction in both basal and stimulated acid production, which alleviates acid‑related symptoms.

The appropriate dose of Lansoprazole EG is determined by the prescribing healthcare professional based on the specific indication, patient age, renal and hepatic function, and treatment duration. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of Lansoprazole EG in pregnancy or while breastfeeding has not been definitively established. Healthcare providers should weigh the potential benefits against any possible risks before prescribing it to pregnant or nursing women, and discuss alternative options when appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Lansoprazole belongs to the proton pump inhibitor class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, its efficacy and safety profile are similar, though individual response and drug‑interaction potential may vary.

Lansoprazole EG should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, excessive heat, and direct sunlight to maintain stability throughout its shelf life.

Lansoprazole EG is taken orally, usually as a tablet or capsule, with or without food as directed by the prescriber. Swallow the dosage form whole with a glass of water and avoid crushing or chewing unless specifically instructed.

Serious risks, though uncommon, include severe allergic reactions (anaphylaxis), Clostridioides difficile‑associated diarrhea, low magnesium levels leading to muscle cramps or cardiac arrhythmias, and increased risk of bone fractures with long‑term use. Patients should seek immediate medical attention if they experience any of these symptoms.

Lansoprazole EG should be avoided in individuals with known hypersensitivity to lansoprazole or other proton pump inhibitors. Caution is also advised for patients with severe liver disease, those taking medications that have major interactions, and anyone for whom the prescriber determines the risks outweigh the benefits.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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