Product image of Lansoprazole Pinewood Laboratories (Lansoprazole) supplied by GNH India

Lansoprazole Pinewood Laboratories

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazole Pinewood Laboratories (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazole Pinewood Laboratories, is a proton pump inhibitor presented as an oral dosage form for oral use. It reduces gastric acid production and is used to treat acid‑related disorders such as GERD, peptic ulcer disease, and erosive esophagitis.

GNH India supplies Lansoprazole Pinewood Laboratories as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pinewood Laboratories Limited

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Indications & Clinical Uses

Lansoprazole is a proton pump inhibitor used to manage conditions associated with excess gastric acid.

  • Gastroesophageal reflux disease (GERD): reduces reflux symptoms and promotes healing of esophageal irritation.
  • Peptic ulcer disease: promotes ulcer healing and prevents recurrence.
  • Erosive esophagitis: heals erosive lesions in the esophagus.
  • Helicobacter pylori eradication (in combination therapy): enhances eradication rates when used with antibiotics.

How It Works

  • Lansoprazole selectively and irreversibly inhibits the H+/K+ ATPase enzyme (the gastric proton pump) located on the secretory surface of gastric parietal cells. By blocking this final step of acid secretion, it markedly reduces both basal and stimulated gastric acid output, allowing the gastric mucosa to heal and decreasing reflux of acidic contents.

Side Effects

Lansoprazole may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Headache: mild pain in the head region.
  • Diarrhea: loose, watery stools.
  • Nausea: feeling of sickness.

Serious or Rare Side Effects

  • Severe allergic reactions (e.g., Stevens‑Johnson syndrome): skin rash, blistering, and mucosal involvement.
  • Clostridium difficile‑associated diarrhea: severe colitis requiring medical attention.
  • Low magnesium levels (hypomagnesemia): muscle cramps, irregular heartbeat.

Precautions & Warnings

Before starting therapy, consider the following precautions.

  • Assess renal and hepatic function: evaluate baseline organ status.
  • Use caution in elderly patients: increased sensitivity to acid suppression.
  • Monitor serum magnesium during prolonged treatment: risk of hypomagnesemia.
  • Avoid abrupt discontinuation: taper if used long‑term to prevent rebound acid hypersecretion.
  • Review concomitant medications: check for potential drug interactions.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Lansoprazole can affect the pharmacokinetics of several medicines.

Major Interactions (Avoid)

  • Clarithromycin: increased lansoprazole levels may lead to toxicity.
  • Ketoconazole: reduced absorption of ketoconazole, risking treatment failure.
  • Atazanavir: decreased atazanavir exposure, compromising HIV therapy.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential increase in anticoagulant effect; monitor INR.
  • Phenytoin: reduced phenytoin concentrations may require dose adjustment.
  • Digoxin: possible rise in digoxin levels; monitor serum concentrations.

Frequently Asked Questions

Lansoprazole Pinewood Laboratories is used to treat acid‑related gastrointestinal conditions. It helps relieve symptoms of gastroesophageal reflux disease, promotes healing of peptic ulcers, and aids in the management of erosive esophagitis. It may also be part of combination therapy for Helicobacter pylori eradication.

Lansoprazole works by irreversibly blocking the H+/K+ ATPase enzyme, also known as the gastric proton pump, in the parietal cells of the stomach. This inhibition stops the final step of acid production, leading to a substantial reduction in gastric acidity and allowing damaged mucosal tissue to heal.

The appropriate dose of Lansoprazole is determined by a qualified prescriber based on the specific condition being treated, the severity of symptoms, patient age, renal and hepatic function, and any concomitant medications. Dosage recommendations are individualized and should not be altered without professional guidance.

Safety data for Lansoprazole in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss the risks and alternatives with their healthcare provider.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the sales team provides pricing, availability, shipping details and any necessary import documentation.

Lansoprazole belongs to the proton pump inhibitor class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs like omeprazole, lansoprazole has a similar efficacy profile but may differ in metabolism pathways, allowing alternative options for patients with specific drug‑interaction concerns.

Lansoprazole should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging to protect it from moisture and light. Do not store in bathrooms or near heat sources, and ensure the container is tightly closed when not in use.

Lansoprazole is taken orally, usually as a tablet or capsule. It should be swallowed whole with a glass of water, preferably before a meal, unless otherwise directed by a healthcare professional. The dosage form is not intended for crushing, chewing, or mixing with food or liquids.

Serious risks, though uncommon, include severe allergic reactions such as Stevens‑Johnson syndrome, Clostridium difficile‑associated colitis, and significant electrolyte disturbances like hypomagnesemia. Patients should seek immediate medical attention if they experience rash, persistent diarrhea, muscle cramps, or irregular heartbeats while using the medication.

Lansoprazole should be avoided in individuals with known hypersensitivity to the drug or any component of the formulation. It is also contraindicated in patients with severe liver disease or those taking medications that require an acidic environment for absorption unless a risk‑benefit assessment is performed by a clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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