Product image of Lansoprazole Teva Pharma (Lansoprazole) supplied by GNH India

Lansoprazole Teva Pharma

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazole Teva Pharma (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazole Teva Pharma, is a proton pump inhibitor presented as an oral tablet for oral use. It reduces gastric acid production and is used to treat conditions such as gastro‑oesophageal reflux disease, erosive esophagitis, peptic ulcer disease and as part of Helicobacter pylori eradication regimens.

GNH India supplies Lansoprazole Teva Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

  • Lansoprazole is a proton pump inhibitor used to manage disorders related to excess gastric acid.
  • Gastro‑oesophageal reflux disease (GERD): provides symptomatic relief and promotes healing of esophageal irritation.
  • Erosive esophagitis: heals erosive lesions in the esophagus.
  • Peptic ulcer disease: promotes ulcer healing and reduces recurrence.
  • Helicobacter pylori eradication (as part of combination therapy): enhances eradication rates by suppressing acid.

How It Works

  • Lansoprazole selectively and irreversibly binds to the sulfhydryl group of the H+/K+ ATPase enzyme (the gastric proton pump) located on the secretory surface of gastric parietal cells. By inhibiting this final step of acid secretion, it markedly reduces both basal and stimulated gastric acid output, leading to an increased gastric pH. The effect persists for up to 72 hours, allowing once‑daily dosing in most treatment regimens.

Side Effects

Lansoprazole may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Headache: mild to moderate headache.
  • Diarrhea: loose stools.
  • Nausea: feeling of queasiness.
  • Abdominal pain: discomfort in the stomach area.
  • Flatulence: increased intestinal gas.

Serious or Rare Side Effects

  • Clostridioides difficile infection: severe colitis.
  • Acute interstitial nephritis: kidney inflammation.
  • Stevens‑Johnson syndrome: severe skin reaction.

Precautions & Warnings

When prescribing Lansoprazole, clinicians should consider several precautionary measures to ensure safe use.

  • Assess renal function: dose adjustment may be needed in severe impairment.
  • Evaluate for Helicobacter pylori infection: confirm eradication status after therapy.
  • Monitor for osteoporosis: long‑term use may affect calcium absorption.
  • Use with caution in elderly: higher risk of fractures and infections.
  • Avoid concomitant use with drugs that require acidic pH for absorption: may reduce their effectiveness.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Lansoprazole can alter the pharmacokinetics of several medicines, leading to clinically relevant interactions.

Major Interactions (Avoid)

  • Antiretroviral protease inhibitors (e.g., atazanavir): reduced absorption, may lose efficacy.
  • Antifungal agents (e.g., ketoconazole, itraconazole): decreased bioavailability.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible increase in INR, monitor coagulation.
  • Clopidogrel: reduced activation, monitor antiplatelet effect.
  • Digoxin: increased serum levels, monitor for toxicity.
  • Methotrexate: reduced renal clearance, monitor levels.

Frequently Asked Questions

Lansoprazole Teva Pharma is indicated for the treatment of gastro‑oesophageal reflux disease (GERD), erosive esophagitis, peptic ulcer disease and as part of combination therapy for Helicobacter pylori eradication. It helps reduce stomach acid, allowing damaged tissue to heal and preventing further injury.

Lansoprazole works by irreversibly inhibiting the gastric H+/K+ ATPase pump located on the secretory surface of parietal cells. This blockade stops the final step of acid production, leading to a sustained increase in gastric pH and a reduction in both basal and stimulated acid secretion.

The appropriate dose of Lansoprazole Teva Pharma is determined by the prescribing healthcare professional based on the specific indication, severity of disease, patient age, renal function and any concomitant medications. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for Lansoprazole in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers should discuss individual circumstances and consider alternative therapies when appropriate.

To order Lansoprazole Teva Pharma, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lansoprazole and other PPIs like omeprazole share the same mechanism of inhibiting the gastric proton pump, but they differ in pharmacokinetic profiles, onset of action and drug‑interaction potential. Lansoprazole may have a slightly longer half‑life and can be less affected by certain CYP2C19 polymorphisms, offering an alternative when other PPIs are unsuitable.

Lansoprazole Teva Pharma should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture, light and excessive heat to maintain potency throughout the shelf life.

Lansoprazole Teva Pharma is taken orally, usually as a whole tablet swallowed with a glass of water. It is generally recommended to take the dose before a meal, preferably in the morning, unless the prescriber advises a different schedule.

Serious but rare risks of Lansoprazole include Clostridioides difficile‑associated colitis, acute interstitial nephritis, and severe skin reactions such as Stevens‑Johnson syndrome. Long‑term therapy may also be linked to decreased calcium absorption, increasing the risk of osteoporosis‑related fractures.

Patients with known hypersensitivity to lansoprazole or any component of the formulation should avoid the product. Caution is advised for individuals with severe liver disease, those taking medications that require an acidic environment for absorption, and patients with a history of certain kidney disorders unless monitored closely.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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