Product image of Lansoprazole Teva Pharma (Lansoprazole) supplied by GNH India

Lansoprazole Teva Pharma

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazole Teva Pharma (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazole Teva Pharma, is a proton pump inhibitor presented as a tablet for oral use. It irreversibly blocks the gastric proton pump, thereby reducing stomach acid production. The medication is indicated for the treatment of gastro‑oesophageal reflux disease, erosive esophagitis, peptic ulcer disease and as part of combination therapy for Helicobacter pylori eradication in adult patients. It is formulated for systemic absorption and is commonly prescribed in standard doses under medical supervision.

GNH India supplies Lansoprazole Teva Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Lansoprazole, a proton pump inhibitor, reduces gastric acid production and is employed in several acid‑related disorders.

  • Gastro‑oesophageal reflux disease (GERD): alleviates heartburn and esophageal irritation.
  • Erosive esophagitis: promotes healing of the damaged esophageal lining.
  • Peptic ulcer disease: supports ulcer healing and symptom relief.
  • Helicobacter pylori eradication: used as part of combination therapy to eradicate H. pylori infection.

How It Works

  • Lansoprazole irreversibly binds to the cysteine residues of the H⁺/K⁺‑ATPase enzyme on gastric parietal cells, inhibiting the final step of acid secretion. This blockade leads to a prolonged reduction in gastric acidity until new proton pumps are synthesized, providing sustained acid suppression.

Side Effects

Lansoprazole may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Headache: mild pain in the head region.
  • Diarrhea: loose, watery stools.
  • Nausea: feeling of sickness or urge to vomit.
  • Abdominal pain: discomfort or cramping in the stomach area.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction with difficulty breathing or swelling.
  • Clostridioides difficile infection: severe colitis presenting with watery diarrhea.
  • Low magnesium (hypomagnesemia): muscle cramps, irregular heartbeat.

Precautions & Warnings

Before initiating lansoprazole therapy, consider the following precautions to ensure safe use.

  • Assess renal function: dose adjustment may be needed in severe impairment.
  • Monitor hepatic function: use with caution in patients with liver disease.
  • Check magnesium levels: long‑term therapy can lead to hypomagnesemia.
  • Avoid abrupt discontinuation: may cause rebound acid hypersecretion.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Lansoprazole can alter the plasma concentrations of several co‑administered medicines; interaction severity varies.

Major Interactions (Avoid)

  • Clopidogrel: reduced activation leading to decreased antiplatelet effect.
  • Atazanavir: markedly decreased absorption and antiviral efficacy.
  • Ritonavir (and other HIV protease inhibitors): reduced plasma levels of the antiviral.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible increase in INR requiring monitoring.
  • Methotrexate: increased exposure may enhance toxicity.

Frequently Asked Questions

Lansoprazole Teva Pharma is prescribed to manage acid‑related gastrointestinal conditions such as gastro‑oesophageal reflux disease (GERD), erosive esophagitis, peptic ulcer disease, and it is also included in combination regimens for the eradication of Helicobacter pylori infection.

Lansoprazole irreversibly inhibits the H⁺/K⁺‑ATPase (gastric proton pump) located on the secretory surface of parietal cells. By blocking this final step of acid secretion, it provides prolonged suppression of gastric acidity, allowing damaged tissues to heal.

The appropriate dose of Lansoprazole Teva Pharma is determined by the prescribing healthcare professional based on the specific indication, severity of disease, patient age, renal and hepatic function, and any concomitant therapies.

Safety data for Lansoprazole in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by a qualified prescriber.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lansoprazole belongs to the proton pump inhibitor (PPI) class, which provides more potent and longer‑lasting acid suppression than H₂‑receptor antagonists. Compared with other PPIs, its efficacy and safety profile are similar, though individual patient response and drug‑interaction potential may vary.

Store the tablets at room temperature, below 25 °C, in the original packaging. Keep them away from moisture, direct sunlight and excessive heat to maintain product stability.

Lansoprazole Teva Pharma is taken orally, usually as a whole tablet swallowed with a glass of water. It is commonly administered before a meal, most often in the morning, unless otherwise directed by the prescriber.

Serious adverse events, although rare, include severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, and significant electrolyte disturbances like hypomagnesemia, which can lead to cardiac arrhythmias or muscle cramps.

Patients with known hypersensitivity to lansoprazole or any component of the formulation should avoid its use. Caution is also advised for individuals with severe liver disease, those on medications that require an acidic environment for absorption, and patients with a history of C. difficile infection.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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