Product image of Lansoprazolo Abc (Lansoprazole) supplied by GNH India

Lansoprazolo Abc

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazolo Abc (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazolo Abc, is a proton pump inhibitor presented as an unspecified/tablet for oral use. It reduces gastric acid secretion and is used to treat acid‑related disorders such as GERD, peptic ulcer disease and Zollinger‑Ellison syndrome.
GNH India supplies Lansoprazolo Abc as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Abc Farmaceutici S.P.A.

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Indications & Clinical Uses

Lansoprazolo Abc, a proton pump inhibitor, acts on conditions caused by excess gastric acid.

  • Gastroesophageal reflux disease (GERD): relieves heartburn and esophageal irritation.
  • Peptic ulcer disease: promotes healing of gastric and duodenal ulcers.
  • Helicobacter pylori eradication (in combination therapy): enhances antibiotic effectiveness to eradicate infection.
  • Zollinger‑Ellison syndrome: controls hyper‑secretion of gastric acid in this rare endocrine disorder.

How It Works

  • Lansoprazole irreversibly binds to the H+/K+ ATPase enzyme (the gastric proton pump) on the parietal cell surface, blocking the final step of acid production. This inhibition reduces both basal and stimulated gastric acid secretion, leading to increased gastric pH and allowing ulcer healing and symptom relief in acid‑related conditions.

Side Effects

Lansoprazolo Abc may cause a range of adverse reactions.

Common Side Effects

  • Headache: mild to moderate pain in the head region.
  • Diarrhea: loose, watery stools occurring intermittently.
  • Nausea: feeling of unease or urge to vomit.
  • Abdominal pain: discomfort or cramping in the stomach area.
  • Flatulence: excess gas causing bloating.
  • Constipation: difficulty passing stools.

Serious or Rare Side Effects

  • Clostridioides difficile infection: severe colitis with watery diarrhea.
  • Severe allergic reaction (anaphylaxis): rash, swelling, difficulty breathing.
  • Elevated liver enzymes: signs of hepatic stress.
  • Stevens‑Johnson syndrome: serious skin and mucous membrane disorder.
  • Interstitial nephritis: kidney inflammation.
  • Hypomagnesemia: low magnesium levels causing muscle cramps or arrhythmias.

Precautions & Warnings

Before prescribing Lansoprazolo Abc, consider the following safety measures.

  • Renal function assessment: evaluate kidney health, especially in patients with impairment.
  • Hepatic monitoring: check liver enzymes periodically during long‑term therapy.
  • CYP2C19 interaction review: consider reduced metabolism in poor metabolizers.
  • Elderly caution: start with the lowest effective dose and monitor for adverse effects.
  • Discontinuation strategy: avoid abrupt cessation after prolonged use to prevent rebound acid hypersecretion.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Lansoprazolo Abc can affect the plasma levels of several concomitant medicines.

Major Interactions (Avoid)

  • Clarithromycin: increased risk of elevated lansoprazole levels.
  • Ketoconazole: reduced absorption of the antifungal.
  • Atazanavir: decreased antiviral efficacy due to higher gastric pH.
  • HIV protease inhibitors (e.g., ritonavir): altered drug exposure.

Moderate Interactions (Monitor Closely)

  • Phenytoin: decreased phenytoin concentrations.
  • Rifampin: reduced lansoprazole effectiveness.
  • Methotrexate: increased risk of toxicity.
  • Digoxin: potential increase in serum digoxin levels.
  • Warfarin: possible alteration of anticoagulant effect.

Frequently Asked Questions

Lansoprazolo Abc contains lansoprazole, a proton pump inhibitor indicated for the treatment of gastro‑oesophageal reflux disease, peptic ulcer disease, Helicobacter pylori eradication regimens (in combination with antibiotics), and Zollinger‑Ellison syndrome, all of which involve excess gastric acid production.

Lansoprazole irreversibly inhibits the gastric H+/K+ ATPase pump located on parietal cells. By blocking this final step of acid secretion, it markedly lowers gastric acidity, allowing ulcer healing and symptom relief in acid‑related disorders.

The appropriate dose of Lansoprazolo Abc is determined by the prescribing healthcare professional based on the specific indication, patient characteristics and clinical response. Dosage regimens are individualized and should follow the prescriber’s instructions.

Safety data for lansoprazole in pregnancy and lactation are limited. The medication should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To request Lansoprazolo Abc, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lansoprazolo Abc belongs to the proton pump inhibitor class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, its efficacy is similar, but individual response and drug‑interaction profiles may vary.

Lansoprazolo Abc should be stored at temperatures below 25 °C, in the original packaging, and protected from moisture and direct sunlight. Keeping the product in a dry, cool environment helps maintain its stability and potency.

Lansoprazolo Abc is taken orally, usually as a tablet swallowed whole with water. It is generally recommended to take the dose before a meal, but patients should follow the specific instructions provided by their prescriber.

Serious adverse events, although rare, can include Clostridioides difficile‑associated diarrhea, severe allergic reactions such as anaphylaxis, liver enzyme elevations, Stevens‑Johnson syndrome, interstitial nephritis and significant hypomagnesemia. Patients should seek immediate medical attention if they experience any of these symptoms.

Lansoprazolo Abc is contraindicated in individuals with known hypersensitivity to lansoprazole or any component of the formulation. Caution is advised for patients with severe liver disease, those taking medications that require an acidic environment for absorption, and patients with known CYP2C19 poor‑metabolizer status.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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