Product image of Lansoprazolo Krka (Lansoprazole) supplied by GNH India

Lansoprazolo Krka

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazolo Krka (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazolo Krka, is a proton pump inhibitor presented as a tablet (strength not specified) for oral use. It reduces gastric acid production and is used to treat acid‑related disorders such as gastro‑esophageal reflux disease and peptic ulcer disease.
GNH India supplies Lansoprazolo Krka as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Krka, D.D., Novo Mesto

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lansoprazolo Krka, a proton pump inhibitor, is employed in the management of several acid‑related conditions.

  • Gastroesophageal reflux disease: alleviates heartburn and esophageal irritation by lowering stomach acidity.
  • Peptic ulcer disease: promotes ulcer healing and prevents recurrence through sustained acid suppression.
  • Helicobacter pylori eradication regimen: enhances antibiotic effectiveness by creating a less acidic gastric environment.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid secretion associated with gastrin‑producing tumors.

How It Works

  • Lansoprazole irreversibly binds to the H+/K+ ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells. By inhibiting this final step of acid production, it markedly reduces both basal and stimulated gastric acid secretion, leading to increased gastric pH and relief of acid‑related symptoms.

Side Effects

Adverse reactions may occur with lansoprazole therapy.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: loose stools, usually transient.
  • Nausea: occasional feeling of queasiness.
  • Abdominal pain: mild discomfort in the stomach area.
  • Flatulence: increased intestinal gas.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Clostridioides difficile infection: severe colitis presenting with watery diarrhea.
  • Severe allergic reactions: rash, swelling, or anaphylaxis requiring immediate medical attention.
  • Low magnesium levels: may cause muscle cramps, irregular heartbeat, or seizures.
  • Vitamin B12 deficiency: long‑term use can lead to anemia and neurological symptoms.
  • Increased risk of bone fractures: especially with prolonged therapy in elderly patients.

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Renal or hepatic impairment: adjust therapy based on liver or kidney function.
  • Elderly patients: monitor for increased sensitivity to side effects.
  • Long‑term use: evaluate need periodically to avoid unnecessary exposure.
  • Concomitant infection risk: be alert for signs of gastrointestinal infections.
  • Discontinuation: taper or monitor for rebound acid hypersecretion when stopping.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Lansoprazole may interact with several medications.

Major Interactions (Avoid)

  • Ketoconazole: reduced absorption due to increased gastric pH.
  • Atazanavir: decreased plasma concentrations, compromising antiviral efficacy.
  • HIV protease inhibitors (e.g., nelfinavir): diminished therapeutic levels.
  • Clopidogrel: reduced activation, potentially lowering antiplatelet effect.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible increase in INR, requiring closer coagulation monitoring.
  • Phenytoin: may lower phenytoin levels, necessitating dose adjustment.
  • Digoxin: potential increase in serum digoxin, watch for toxicity.
  • Methotrexate: higher systemic exposure, monitor renal function and blood counts.
  • Diazepam: enhanced sedation, observe for excessive CNS depression.

Frequently Asked Questions

Lansoprazolo Krka contains lansoprazole, a proton pump inhibitor indicated for gastro‑esophageal reflux disease, peptic ulcer disease, Helicobacter pylori eradication regimens, and Zollinger‑Ellison syndrome. It works by reducing stomach acid, helping to heal ulcers and relieve reflux symptoms.

Lansoprazole irreversibly blocks the H+/K+ ATPase enzyme, also known as the gastric proton pump, on the surface of parietal cells. This inhibition stops the final step of acid production, leading to a sustained increase in gastric pH and decreased acidity.

The appropriate dose of Lansoprazolo Krka is determined by the prescribing healthcare professional based on the specific indication, patient age, renal and hepatic function, and treatment duration. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for lansoprazole in pregnancy and lactation are limited. The prescriber should weigh the potential benefits against any possible risks to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After verification of trade or institutional credentials, the sales team will provide pricing, availability, shipping details, and any necessary import documentation.

Lansoprazolo Krka (lansoprazole) belongs to the same class as omeprazole, esomeprazole, pantoprazole, and rabeprazole. All share the mechanism of proton pump inhibition, but they differ slightly in pharmacokinetic profiles, drug‑interaction potential, and dosing frequency. Choice of agent often depends on physician preference, patient response, and specific drug‑interaction considerations.

Store Lansoprazolo Krka at room temperature, below 25 °C (77 °F). Keep the tablets in the original packaging, protect them from moisture, heat, and direct sunlight to maintain product stability.

Lansoprazolo Krka is taken orally, usually as a whole tablet swallowed with water. It is generally recommended to take the dose before a meal, often in the morning, unless the prescriber advises otherwise.

Serious risks include Clostridioides difficile‑associated diarrhea, severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome, low magnesium levels, vitamin B12 deficiency with long‑term use, and an increased risk of bone fractures, particularly in elderly patients on prolonged therapy.

Patients with known hypersensitivity to lansoprazole or any component of the formulation should avoid this medication. Caution is also advised for individuals with severe liver disease, those taking medications that require an acidic gastric environment, and patients with a history of osteoporosis when long‑term therapy is considered.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Lansoprazole

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT