Lansoyl Framboise En Recipient Unidose (Liquid Paraffin)

Liquid paraffin acts locally in the gastrointestinal tract to relieve constipation and related bowel irregularities.

• Constipation: softens stool and eases its passage, providing relief from occasional constipation.
• Hard stool: lubricates intestinal contents, reducing hardness and facilitating evacuation.
• Bowel irregularity: improves stool consistency, helping normalize bowel movements.

• Liquid paraffin works as an inert, non‑absorbable oil that coats the intestinal mucosa. By forming a slippery layer, it reduces water reabsorption from the fecal mass, keeping the stool moist and decreasing friction. This lubricating effect allows the stool to move more easily through the colon, promoting regular bowel movements without stimulating intestinal motility. The action is confined to the lumen and does not involve systemic absorption.

Liquid paraffin may cause a range of adverse reactions, most of which are mild and related to its oily nature.

Common Side Effects

• Abdominal cramps: mild discomfort in the lower abdomen.
• Bloating: sensation of fullness or gas accumulation.
• Oily or greasy stools: visible oil residue in the stool.
• Nausea: feeling of unease or urge to vomit.
• Flatulence: excess intestinal gas.
• Diarrhea: loose, watery stools.

Serious or Rare Side Effects

• Anal leakage: uncontrolled discharge of oily stool.
• Allergic reaction: rash, itching, swelling, or difficulty breathing.
• Rectal irritation: burning or pain in the rectal area.
• Pulmonary aspiration: inhalation of oil leading to lung inflammation.
• Severe abdominal pain: intense, persistent pain requiring medical attention.
• Fecal impaction (rare): hard stool blockage despite laxative use.

When using liquid paraffin, certain precautions should be observed to ensure safe and effective use.

• Use in children under 2 years: avoid unless directed by a physician.
• Intestinal obstruction: contraindicated in patients with known blockage or severe motility disorders.
• Dysphagia: administer with caution to patients with swallowing difficulties.
• Concomitant laxatives: avoid using multiple laxatives simultaneously without medical advice.
• Electrolyte imbalance: monitor patients at risk for dehydration or electrolyte disturbances.
• Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Liquid paraffin can affect the absorption and efficacy of several other medicines.

Major Interactions (Avoid)

• Fat‑soluble vitamins (A, D, E, K): reduced absorption leading to deficiency.
• Warfarin: decreased anticoagulant effect due to impaired vitamin K absorption.
• Digoxin: lower plasma levels from altered intestinal uptake.
• Cyclosporine: diminished immunosuppressive activity.
• Antiretroviral agents: possible decreased bioavailability.

Moderate Interactions (Monitor Closely)

• Oral contraceptives: may reduce hormone absorption.
• Antacids: potential alteration of oil dispersion.
• Cholesterol‑lowering agents (statins): slight decrease in absorption.
• Antibiotics (tetracyclines): possible reduced uptake.
• Thyroid hormone replacement: monitor serum levels.