Product image of Lanthan Mylan (Lanthanum) supplied by GNH India

Lanthan Mylan

Active Ingredient:
Lanthanum
Origin:
EU

Lanthan Mylan (Lanthanum)

Lanthanum, the active ingredient in Lanthan Mylan, is a phosphate binder presented as an oral formulation for oral use. It binds dietary phosphate in the gastrointestinal tract to reduce serum phosphate levels in patients with chronic kidney disease. GNH India supplies Lanthan Mylan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, dialysis centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Mylan Germany Gmbh

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Indications & Clinical Uses

Lanthan Mylan is a phosphate‑binding agent indicated for conditions associated with elevated serum phosphate.

  • Chronic kidney disease on dialysis: reduces serum phosphate levels and helps maintain mineral balance.
  • Chronic kidney disease not on dialysis: assists in controlling phosphate accumulation.
  • Hyperphosphatemia from other causes: provides oral phosphate binding to lower serum phosphate.

How It Works

  • Lanthanum carbonate dissociates in the acidic gastric environment to release lanthanum ions, which bind dietary phosphate to form an insoluble lanthanum phosphate complex. This complex is not absorbed and is eliminated in the feces, thereby decreasing intestinal phosphate absorption and lowering serum phosphate concentrations.

Side Effects

Lanthan Mylan may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate discomfort in the stomach.
  • Constipation: reduced bowel movements.
  • Diarrhea: loose stools.
  • Abdominal pain: cramping or discomfort.
  • Dyspepsia: indigestion or heartburn.
  • Metallic taste: altered taste sensation.

Serious or Rare Side Effects

  • Intestinal obstruction: blockage of the gastrointestinal tract.
  • Severe allergic reaction (anaphylaxis): difficulty breathing, swelling, rash.
  • Hypophosphatemia: excessively low phosphate levels.
  • Granulomatous inflammation: localized tissue reaction.
  • Hypercalcemia: elevated calcium levels, especially when combined with calcium‑containing agents.
  • Liver enzyme elevation: abnormal liver function tests.

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Monitor serum phosphate: adjust dose based on laboratory results.
  • Assess calcium levels: avoid concurrent hypercalcemia.
  • Evaluate gastrointestinal health: use cautiously in patients with bowel obstruction or severe constipation.
  • Avoid concomitant antacids containing aluminum or magnesium: may reduce binding efficacy.
  • Pregnancy and lactation: limited data, prescribe only if potential benefit outweighs risk.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Lanthan Mylan can interact with several medications.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: may significantly reduce phosphate‑binding capacity.
  • Iron supplements: can interfere with lanthanum binding.
  • Calcium carbonate: may diminish effectiveness of the phosphate binder.

Moderate Interactions (Monitor Closely)

  • Vitamin D analogues: monitor calcium and phosphate levels closely.
  • Phosphate‑containing laxatives: may counteract the drug's effect.
  • Renal transplant immunosuppressants: watch for altered phosphate balance.

Frequently Asked Questions

Lanthan Mylan is an oral phosphate‑binding medication used to lower elevated serum phosphate levels in patients with chronic kidney disease, including those on dialysis, and in other conditions where hyperphosphatemia is present.

Lanthanum carbonate releases lanthanum ions in the stomach, which bind dietary phosphate to form an insoluble complex. This complex is not absorbed and is eliminated in the feces, thereby reducing the amount of phosphate absorbed into the bloodstream.

The dose of Lanthan Mylan is individualized and set by the prescribing clinician based on the patient’s serum phosphate levels, kidney function, and overall treatment plan. No fixed regimen is provided here.

Safety data for lanthanum in pregnancy and lactation are limited. It should be used only if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under close medical supervision.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

The primary alternative phosphate binders are sevelamer and calcium‑based binders. Lanthanum offers a high binding capacity with a lower pill burden than calcium binders and does not contain calcium, reducing the risk of hypercalcemia, whereas sevelamer may cause more gastrointestinal upset.

Store Lanthan Mylan at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture and direct sunlight to maintain stability and efficacy.

Lanthan Mylan is taken orally, usually with meals or snacks to maximize phosphate binding. The tablets should be swallowed whole with a sufficient amount of water, unless otherwise directed by the prescriber.

Serious risks include intestinal obstruction, severe allergic reactions such as anaphylaxis, and excessively low phosphate levels (hypophosphatemia). Patients should seek immediate medical attention if they experience severe abdominal pain, swelling, difficulty breathing, or unusual laboratory changes.

Lanthan Mylan should be avoided in patients with known hypersensitivity to lanthanum or any component of the formulation, those with active gastrointestinal obstruction, and individuals who cannot tolerate oral medications. Caution is also advised for patients with severe liver disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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