Product image of Lanthane Viatris (Lanthanum) supplied by GNH India

Lanthane Viatris

Active Ingredient:
Lanthanum
Origin:
EU

Lanthane Viatris (Lanthanum)

Lanthanum, the active ingredient in Lanthane Viatris, is a phosphate binder presented as an oral formulation for oral use. It binds dietary phosphate in the gastrointestinal tract, forming insoluble complexes that are excreted, and is employed to treat hyperphosphatemia in patients with chronic kidney disease, particularly those on dialysis.

GNH India supplies Lanthane Viatris as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide, with distribution originating from the European Union market.

Manufacturer / TM Owner

Viatris Sante

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Indications & Clinical Uses

  • Lanthane Viatris is a phosphate binder used to manage elevated serum phosphate levels in chronic kidney disease.
  • Hyperphosphatemia in chronic kidney disease: lowers serum phosphate concentrations.
  • Patients on dialysis: helps maintain phosphate balance and reduces the need for strict dietary restrictions.
  • End‑stage renal disease: contributes to lowering the risk of vascular calcification associated with high phosphate.

How It Works

  • Lanthanum acts locally in the gastrointestinal tract by binding dietary phosphate ions. The resulting lanthanum‑phosphate complexes are insoluble and are eliminated in the feces, preventing absorption of phosphate into the bloodstream. This reduction in intestinal phosphate uptake leads to lower serum phosphate levels without systemic absorption of the metal, and the binding capacity is concentration‑dependent throughout the stomach and intestines.

Side Effects

Lanthane Viatris may cause gastrointestinal and metabolic adverse reactions.

Common Side Effects

  • Nausea
  • Constipation
  • Abdominal discomfort
  • Metallic taste

Serious or Rare Side Effects

  • Severe constipation leading to bowel obstruction
  • Hypophosphatemia (excessively low serum phosphate)
  • Gastrointestinal ulceration or bleeding

Precautions & Warnings

  • Before initiating therapy, consider the following precautions.
  • Monitor serum phosphate: check levels regularly to adjust therapy.
  • Assess calcium balance: avoid concurrent high calcium intake that may cause hypercalcemia.
  • Evaluate gastrointestinal health: patients with existing bowel disorders may have increased risk of obstruction.
  • Review concomitant phosphate binders: avoid using multiple binders simultaneously without medical supervision.
  • Store below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Lanthane Viatris can interact with several medicines; awareness helps maintain efficacy and safety.

Major Interactions (Avoid)

  • Iron supplements (e.g., ferrous sulfate): reduce lanthanum binding efficacy.
  • Calcium carbonate or calcium acetate: compete for phosphate binding sites.
  • Sevelamer: additive phosphate binding may cause excessive phosphate depletion.

Moderate Interactions (Monitor Closely)

  • Vitamin D analogs (e.g., calcitriol): may increase calcium absorption, requiring monitoring.
  • Proton pump inhibitors: may alter gastric pH and affect lanthanum solubility.

Frequently Asked Questions

Lanthane Viatris is an oral phosphate binder indicated for the treatment of hyperphosphatemia in patients with chronic kidney disease, especially those receiving dialysis. By reducing intestinal phosphate absorption, it helps maintain target serum phosphate levels and supports overall mineral balance.

Lanthanum acts locally in the gastrointestinal tract, where it binds dietary phosphate ions to form insoluble lanthanum‑phosphate complexes. These complexes are not absorbed and are eliminated in the feces, thereby decreasing the amount of phosphate that enters the bloodstream and lowering serum phosphate concentrations.

The appropriate dose of Lanthane Viatris is determined by the prescribing clinician based on the patient’s serum phosphate levels, dietary intake, and dialysis regimen. The prescriber will adjust the amount to achieve the desired phosphate control while monitoring for safety.

Safety data for lanthanum‑based phosphate binders in pregnancy and lactation are limited. The product should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and the necessary import documentation.

Compared with calcium‑based binders, lanthanum does not increase calcium load, reducing the risk of hypercalcemia. Unlike sevelamer, lanthanum generally has a lower pill burden and does not affect lipid profiles. Choice of binder depends on individual patient factors, tolerability, and physician preference.

Store Lanthane Viatris at temperatures below 25 °C in its original packaging. Protect the product from moisture, direct sunlight, and extreme humidity. Do not refrigerate or freeze the tablets, and keep them out of reach of children.

Lanthane Viatris is taken orally, usually with meals. The tablets should be swallowed whole with a full glass of water unless the prescribing information advises otherwise. Consistency in timing with respect to food helps maintain optimal phosphate‑binding efficacy.

The most serious adverse events include severe constipation that can progress to bowel obstruction, marked hypophosphatemia leading to muscle weakness or cardiac issues, and gastrointestinal ulceration or bleeding. Patients should report any persistent abdominal pain, inability to pass stool, or signs of bleeding promptly.

Lanthane Viatris should be avoided in patients with known hypersensitivity to lanthanum or any excipients, those with active gastrointestinal obstruction, severe bowel disorders, or conditions that predispose to ulceration. It is also contraindicated in individuals for whom phosphate binding is not clinically indicated.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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