Product image of Lantus Solostar (Insulin Glargine) supplied by GNH India

Lantus Solostar

Active Ingredient:
Insulin Glargine
Origin:
EU

Lantus Solostar (Insulin Glargine)

Insulin glargine, the active ingredient in Lantus Solostar, is a long‑acting insulin analog presented as a solution for subcutaneous use. It provides basal insulin coverage for patients with diabetes mellitus type 1 and type 2.

GNH India supplies Lantus Solostar as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sanofi-Aventis Deutschland Gmbh

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Indications & Clinical Uses

  • Lantus Solostar is a basal insulin that acts on the glucose regulation pathway to maintain steady blood‑sugar levels.
  • Diabetes mellitus type 1: provides long‑acting basal insulin to control fasting glucose.
  • Diabetes mellitus type 2: supplies basal insulin support when oral agents are insufficient.

How It Works

  • Insulin glargine binds to insulin receptors on peripheral tissues, stimulating glucose uptake in muscle and adipose tissue while suppressing hepatic glucose production. Its altered amino‑acid sequence and formulation create a microprecipitate after subcutaneous injection, resulting in a slow, steady release that mimics physiologic basal insulin secretion for up to 24 hours.

Side Effects

Common Side Effects

  • Hypoglycemia: low blood glucose episodes, especially if dosing is excessive.
  • Injection site reactions: redness, swelling, or itching at the injection site.
  • Weight gain: modest increase due to improved glucose utilization.

Serious or Rare Side Effects

  • Severe hypoglycemia: can lead to loss of consciousness or seizures.
  • Allergic reactions: rash, urticaria, or angioedema.
  • Anaphylaxis: rare but life‑threatening systemic allergic response.
  • Lipodystrophy: abnormal fat distribution at injection sites.
  • Edema: fluid retention causing swelling of extremities.

Precautions & Warnings

When using Lantus Solostar, consider the following precautions:

  • Dose adjustment: titrate based on regular glucose monitoring and clinical response.
  • Renal impairment: monitor closely as insulin clearance may be reduced.
  • Hypoglycemia risk: educate patients on recognizing and treating low blood sugar.
  • Pregnancy and lactation: use only if benefits outweigh potential risks.
  • Storage: Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Lantus Solostar may interact with other medications as follows:

Major Interactions (Avoid)

  • Sulfonylureas: combined use can markedly increase hypoglycemia risk.
  • Beta‑blockers: may mask typical hypoglycemia symptoms, complicating detection.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: may enhance insulin sensitivity, requiring dose review.
  • Thiazide diuretics: can raise blood glucose, potentially altering insulin needs.
  • Oral contraceptives: may affect insulin requirements, necessitating monitoring.

Frequently Asked Questions

Lantus Solostar is a long‑acting insulin analog used to provide basal insulin coverage in patients with diabetes mellitus type 1 and type 2, helping to maintain stable blood‑glucose levels throughout the day.

Insulin glargine binds to insulin receptors, promoting glucose uptake in muscle and fat cells while suppressing hepatic glucose production. Its formulation creates a slow, continuous release after subcutaneous injection, delivering a steady basal insulin effect for up to 24 hours.

The dose of Lantus Solostar is individualized and determined by a qualified prescriber based on the patient’s blood‑glucose monitoring, body weight, diet, and overall treatment plan. No fixed dosing regimen is provided here.

Insulin glargine may be used during pregnancy or lactation only if the potential benefits justify the potential risks. Decisions should be made by the treating physician in consultation with the patient.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Lantus Solostar (insulin glargine) offers a once‑daily, long‑acting basal insulin profile with minimal peak effect, similar to other insulin glargine products. Compared with intermediate‑acting insulins like NPH, it provides more predictable glucose control and a lower risk of nocturnal hypoglycemia.

Lantus Solostar should be stored in a refrigerator at 2‑8 °C, protected from light, and must not be frozen or shaken. Once in use, the vial can be kept at room temperature (up to 30 °C) for a maximum of 28 days, as indicated on the label.

Lantus Solostar is administered by subcutaneous injection, typically once daily at the same time each day. Injection sites may include the abdomen, thigh, or upper arm, rotating sites to reduce local reactions.

The most serious risks include severe hypoglycemia, which can lead to loss of consciousness or seizures, and rare allergic reactions such as anaphylaxis. Patients should be educated to recognize early signs and seek immediate medical attention if they occur.

Lantus Solostar should not be used by individuals with known hypersensitivity to insulin glargine or any of its excipients. Caution is also advised for patients with severe renal or hepatic impairment, and it is contraindicated in cases of hypoglycemia.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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