Product image of Lanzo (Lansoprazole) supplied by GNH India

Lanzo

Active Ingredient:
Lansoprazole
Origin:
EU

Lanzo (Lansoprazole)

Lansoprazole, the active ingredient in Lanzo, is a proton pump inhibitor presented as an oral tablet for oral use. It reduces gastric acid production and is used to treat conditions such as gastro‑oesophageal reflux disease and peptic ulcer disease in adult patients.

GNH India supplies Lanzo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for bulk and packaged orders across multiple regulatory markets globally.

Manufacturer / TM Owner

Pfizer Ab

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Indications & Clinical Uses

  • Lansoprazole is employed to manage acid‑related disorders by suppressing gastric secretion.
  • Gastro‑oesophageal reflux disease (GERD): alleviates heartburn and regurgitation, promotes healing of esophageal mucosa, and reduces acid exposure.
  • Peptic ulcer disease: facilitates ulcer healing by maintaining a higher gastric pH, thereby protecting the ulcer base from acid damage.
  • NSAID‑induced ulcer prevention: reduces the risk of ulcer formation in patients requiring chronic non‑steroidal anti‑inflammatory drug therapy.
  • Helicobacter pylori eradication (in combination therapy): enhances the effectiveness of antibiotic regimens by creating a less acidic gastric environment.

How It Works

  • Lansoprazole irreversibly binds to the H+/K+ ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells. By blocking this final step of acid secretion, it markedly reduces both basal and stimulated gastric acid output, leading to an increased gastric pH that persists for up to 72 hours after a single dose. The inhibition is dose‑dependent and does not affect other gastric enzymes, providing a targeted approach to acid control.

Side Effects

Lansoprazole may be associated with a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Headache: mild headache reported in some patients.
  • Diarrhea: loose stools or increased frequency.
  • Abdominal pain: discomfort or cramping in the stomach area.
  • Nausea: feeling of sickness or urge to vomit.

Serious or Rare Side Effects

  • Clostridioides difficile infection: severe colitis may occur.
  • Acute interstitial nephritis: kidney inflammation presenting with rash and fever.
  • Osteoporotic fractures: increased risk of hip, wrist or vertebral fractures with long‑term use.

Precautions & Warnings

When prescribing lansoprazole, clinicians should consider several safety and handling precautions.

  • Assess renal function: dose adjustment may be needed in severe renal impairment.
  • Evaluate for CYP2C19 interactions: genetic variability can affect drug levels.
  • Monitor for hypomagnesemia: prolonged therapy may lower serum magnesium.
  • Use caution in elderly: higher risk of bone fractures and infections.
  • Store at ambient temperature: keep below 25°C in the original container, protect from moisture.

Avoid Interactions

Lansoprazole can alter the pharmacokinetics of several co‑administered medicines.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet effect may increase cardiovascular risk.
  • Atazanavir: decreased absorption leading to loss of antiviral efficacy.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential increase in INR, monitor coagulation parameters.
  • Digoxin: increased serum levels, observe for toxicity signs.
  • Methotrexate: higher exposure may cause toxicity, especially at high doses.

Frequently Asked Questions

Lanzo contains lansoprazole, which is used to treat acid‑related conditions such as gastro‑oesophageal reflux disease, peptic ulcer disease, and to prevent ulcers associated with long‑term NSAID use. It may also be part of combination therapy for Helicobacter pylori eradication.

Lansoprazole blocks the H+/K+ ATPase enzyme, also known as the gastric proton pump, in the stomach lining. By irreversibly inhibiting this pump, it reduces the secretion of gastric acid, thereby raising stomach pH and allowing damaged tissue to heal.

The appropriate dose of Lanzo is determined by the prescribing healthcare professional based on the specific indication, patient age, renal function and other clinical factors. Patients should follow the prescriber’s instructions and not alter the dose on their own.

Safety data for lansoprazole in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To order Lanzo, submit an enquiry on the product page at gnhindia.com indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lanzo (lansoprazole) belongs to the proton pump inhibitor class, which generally provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs like omeprazole, lansoprazole has a similar efficacy profile but may differ slightly in metabolism and drug‑interaction potential.

Lanzo should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in humid or excessively hot environments.

Lanzo is taken orally, usually as a whole tablet swallowed with water. It is generally recommended to take the dose before a meal, but patients should follow the specific instructions provided by their prescriber.

Serious but uncommon risks include Clostridioides difficile‑associated colitis, acute interstitial nephritis, and an increased incidence of osteoporotic fractures with long‑term use. Patients should be monitored for persistent diarrhea, unexplained kidney problems or signs of bone weakness.

Lanzo should be avoided in individuals with known hypersensitivity to lansoprazole or any other components of the formulation. Caution is also advised for patients with severe liver disease, and it should be used only under medical supervision in those with a history of certain infections or bone disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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