Product image of Lanzol (Lansoprazole) supplied by GNH India

Lanzol

Active Ingredient:
Lansoprazole
Origin:
EU

Lanzol (Lansoprazole)

Lansoprazole, the active ingredient in Lanzol, is a proton pump inhibitor presented as a tablet for oral use. It reduces gastric acid production and is used to treat conditions such as gastro‑oesophageal reflux disease, peptic ulcers and related disorders in adults.

GNH India supplies Lanzol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Rowex Ltd

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Indications & Clinical Uses

Lansoprazole is a proton pump inhibitor used to manage acid‑related gastrointestinal conditions.

  • Gastro‑oesophageal reflux disease (GERD): provides symptomatic relief and promotes healing of esophageal irritation.
  • Erosive esophagitis: heals erosive lesions and reduces recurrence risk.
  • Peptic ulcer disease: accelerates ulcer healing and lowers the chance of recurrence.
  • Helicobacter pylori eradication regimens: used as part of combination therapy to improve eradication rates.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid secretion.

How It Works

  • Lansoprazole selectively and irreversibly inhibits the H+/K+ ATPase (proton pump) located on the secretory surface of gastric parietal cells. By blocking this final step of acid secretion, it markedly reduces both basal and stimulated gastric acid output, leading to an increase in gastric pH and facilitating mucosal healing in acid‑related disorders.

Side Effects

Lansoprazole may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: usually self‑limiting.
  • Nausea: occasional, may improve with food.
  • Abdominal pain: mild discomfort.
  • Flatulence: increased gas.
  • Constipation: infrequent.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis): requires immediate medical attention.
  • Clostridioides difficile infection: can cause severe colitis.
  • Low magnesium levels (hypomagnesemia): may lead to muscle cramps or arrhythmias.
  • Interstitial nephritis: rare kidney inflammation.

Precautions & Warnings

When prescribing Lanzol, clinicians should consider several safety and handling points.

  • Assess renal function: adjust use in severe renal impairment.
  • Monitor for infection: prolonged therapy may increase risk of gastrointestinal infections.
  • Check magnesium levels: long‑term use can lead to hypomagnesemia.
  • Avoid abrupt discontinuation: may cause rebound acid hypersecretion.
  • Pregnancy and lactation: use only if benefit outweighs risk, as safety data are limited.
  • Store at ambient temperature: keep below 25 °C, in original packaging, protected from moisture.

Avoid Interactions

Lansoprazole can affect the plasma concentrations of several co‑administered medicines.

Major Interactions (Avoid)

  • Ketoconazole: reduced absorption, avoid co‑administration.
  • Atazanavir: markedly decreased exposure, avoid.
  • Clopidogrel: reduced activation, avoid.

Moderate Interactions (Monitor Closely)

  • Warfarin: may increase INR, monitor coagulation.
  • Methotrexate: increased serum levels, monitor toxicity.
  • Digoxin: may increase levels, monitor cardiac function.

Frequently Asked Questions

Lanzol contains lansoprazole, a proton pump inhibitor indicated for the treatment of gastro‑oesophageal reflux disease, erosive esophagitis, peptic ulcer disease, as part of Helicobacter pylori eradication regimens, and for controlling acid hypersecretion in Zollinger‑Ellison syndrome.

Lansoprazole blocks the H+/K+ ATPase enzyme (the proton pump) in gastric parietal cells, preventing the final step of acid secretion. This results in a sustained increase in gastric pH, allowing damaged mucosa to heal and reducing symptoms caused by excess acid.

The appropriate dose of Lanzol is determined by the prescribing clinician based on the specific indication, patient age, renal function and other clinical factors. Dosage regimens are individualized and should follow the prescriber’s instructions.

Safety data for lansoprazole in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.

To order Lanzol, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lanzol (lansoprazole) belongs to the proton pump inhibitor class, which generally provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, lansoprazole has a similar efficacy profile but may differ slightly in metabolism and drug‑interaction potential.

Lanzol tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original container, protect from moisture and direct sunlight, and ensure the packaging remains tightly closed until use.

Lanzol is taken orally, usually as a whole tablet swallowed with a glass of water. It is typically administered before a meal, but the exact timing should follow the prescriber’s guidance.

Serious adverse events, although rare, include severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, low magnesium levels that can cause muscle cramps or cardiac arrhythmias, and interstitial nephritis. Patients should seek immediate medical attention if they experience any of these symptoms.

Lanzol is contraindicated in individuals with known hypersensitivity to lansoprazole or any component of the formulation. Caution is advised for patients with severe liver disease, those taking medications that require an acidic environment for absorption, and patients with a history of allergic reactions to other proton pump inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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