Product image of Lanzol (Lansoprazole) supplied by GNH India

Lanzol

Active Ingredient:
Lansoprazole
Origin:
EU

Lanzol (Lansoprazole)

Lansoprazole, the active ingredient in Lanzol, is a proton pump inhibitor presented as an oral tablet for oral use. It reduces gastric acid secretion and is used to treat acid‑related disorders such as gastro‑oesophageal reflux disease and peptic ulcer disease.

GNH India supplies Lanzol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Rowex Ltd

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Indications & Clinical Uses

Lanzol (lansoprazole) acts on the gastric proton pump to manage several acid‑related conditions.

  • Gastro‑oesophageal reflux disease (GERD): relieves heartburn and esophageal irritation.
  • Peptic ulcer disease: promotes healing of gastric and duodenal ulcers.
  • NSAID‑induced ulcer prophylaxis: prevents ulcer formation in patients taking non‑steroidal anti‑inflammatory drugs.
  • Helicobacter pylori eradication (in combination therapy): enhances bacterial clearance when used with antibiotics.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid production.

How It Works

  • Lansoprazole irreversibly binds to the H+/K+ ATPase enzyme (gastric proton pump) located on the secretory surface of parietal cells. By inhibiting this final step of acid production, it markedly reduces basal and stimulated gastric acid secretion, thereby increasing gastric pH and allowing mucosal healing.

Side Effects

Adverse reactions may occur with lansoprazole therapy.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhoea: watery stools, usually transient.
  • Nausea: occasional upset stomach.
  • Abdominal pain: cramping or discomfort.
  • Flatulence: increased gas.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Clostridioides difficile infection: severe colitis.
  • Severe allergic reactions: rash, angioedema, anaphylaxis.
  • Stevens‑Johnson syndrome/toxic epidermal necrolysis: skin blistering.
  • Liver enzyme elevation: hepatitis signs.
  • Hypomagnesemia: low serum magnesium.
  • Bone fracture risk: long‑term use may affect bone density.

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Assess renal and hepatic function: adjust use if impairment exists.
  • Monitor for infections: especially C. difficile.
  • Evaluate need for long‑term therapy: reassess periodically.
  • Use caution in patients with osteoporosis: consider bone health.
  • Avoid abrupt discontinuation: may cause rebound acid hypersecretion.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Lansoprazole may interact with several medications.

Major Interactions (Avoid)

  • Atazanavir, nelfinavir, ketoconazole: reduced absorption and efficacy.
  • Clopidogrel: decreased activation, reduced antiplatelet effect.
  • Warfarin: possible increase in INR, enhanced anticoagulation.

Moderate Interactions (Monitor Closely)

  • Digoxin: increased serum levels, monitor cardiac function.
  • Methotrexate: reduced clearance, watch for toxicity.
  • HIV protease inhibitors: altered plasma concentrations, adjust dosing.
  • Vitamin B12: long‑term use may impair absorption, monitor levels.

Frequently Asked Questions

Lanzol contains lansoprazole, which is prescribed for acid‑related disorders such as gastro‑oesophageal reflux disease, peptic ulcer disease, NSAID‑induced ulcer prevention, Helicobacter pylori eradication when combined with antibiotics, and Zollinger‑Ellison syndrome.

Lansoprazole blocks the H+/K+ ATPase enzyme, also known as the gastric proton pump, on parietal cells. This irreversible inhibition stops the final step of acid secretion, raising gastric pH and allowing ulcer healing and symptom relief.

The appropriate dose of Lanzol is determined by a qualified prescriber based on the specific indication, patient characteristics, and clinical response. Patients should follow the dosing instructions provided by their healthcare professional.

Safety data for lansoprazole in pregnancy and lactation are limited. Prescribers should weigh potential benefits against possible risks and consider alternative therapies when appropriate. Women who are pregnant or nursing should discuss use with their doctor.

To request Lanzol, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lanzol (lansoprazole) is a potent PPI with a rapid onset of action and a half‑life that supports once‑daily dosing for most indications. Compared with omeprazole or esomeprazole, it offers similar efficacy but may have a slightly different metabolic profile, which can influence drug‑interaction potential.

Lanzol should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and do not use it after the expiry date.

Lanzol is taken orally, usually as a whole tablet swallowed with water. It is generally recommended to take the dose before a meal, but patients should follow the specific instructions given by their prescriber.

Serious adverse events, although rare, include Clostridioides difficile infection, severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, liver enzyme abnormalities, low magnesium levels, and increased risk of bone fractures with long‑term use.

Lanzol is contraindicated in patients with known hypersensitivity to lansoprazole or any component of the formulation. Caution is advised for individuals with severe liver disease, those taking medications that require an acidic environment for absorption, and patients with a history of osteoporosis or fractures.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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