Product image of Lanzul S (Lansoprazole) supplied by GNH India

Lanzul S

Active Ingredient:
Lansoprazole
Origin:
EU

Lanzul S (Lansoprazole)

Lansoprazole, the active ingredient in Lanzul S, is a proton pump inhibitor presented as a tablet for oral use. It treats acid‑related disorders such as gastro‑oesophageal reflux disease, peptic ulcer disease and Helicobacter pylori infection in adults.

GNH India supplies Lanzul S as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Krka, D.D., Novo Mesto

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Indications & Clinical Uses

Lansoprazole is a proton pump inhibitor used to reduce gastric acid production in several acid‑related conditions.

  • Gastro‑oesophageal reflux disease (GERD): reduces reflux symptoms and promotes healing of esophageal irritation.
  • Peptic ulcer disease: facilitates ulcer healing by decreasing gastric acidity.
  • Helicobacter pylori eradication: used in combination therapy to improve eradication rates.
  • Erosive oesophagitis: promotes mucosal healing and symptom relief.

How It Works

  • Lansoprazole selectively and irreversibly inhibits the H+/K+ ATPase enzyme (the gastric proton pump) located on the secretory surface of gastric parietal cells. By blocking this final step of acid secretion, it markedly reduces both basal and stimulated gastric acid output, leading to an increase in gastric pH and providing an environment conducive to ulcer healing and symptom control.

Side Effects

Lansoprazole may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Headache: mild to moderate pain often resolving without intervention.
  • Diarrhea: loose stools that may improve with continued therapy.
  • Nausea: feeling of queasiness, sometimes accompanied by mild stomach upset.
  • Abdominal pain: discomfort or cramping in the upper abdomen.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis): difficulty breathing, swelling of face or throat.
  • Clostridioides difficile‑associated diarrhea: persistent watery stools with abdominal pain.
  • Interstitial nephritis: inflammation of kidney tissue that may affect renal function.

Precautions & Warnings

When prescribing or dispensing Lanzul S, consider the following safety measures.

  • Assess renal function: adjust use in patients with severe renal impairment.
  • Avoid concomitant use with contraindicated drugs: e.g., atazanavir may have reduced absorption.
  • Monitor magnesium levels during long‑term therapy: risk of hypomagnesemia.
  • Use with caution in hepatic disease: dose may need adjustment.
  • Store at ambient temperature: keep in the original pack, protect from moisture and light.

Avoid Interactions

Lanzul S can interact with several medicines; awareness of the interaction level is essential.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet effect, may increase cardiovascular risk.
  • Atazanavir (and other protease inhibitors): decreased antiviral absorption, compromising efficacy.
  • Warfarin: potential increase in INR, requiring closer coagulation monitoring.

Moderate Interactions (Monitor Closely)

  • Digoxin: possible increase in serum digoxin levels, monitor for toxicity.
  • Methotrexate: reduced renal clearance may raise methotrexate concentrations, monitor renal function and drug levels.

Frequently Asked Questions

Lanzul S contains lansoprazole, which is prescribed for acid‑related disorders such as gastro‑oesophageal reflux disease (GERD), peptic ulcer disease, Helicobacter pylori eradication regimens, and erosive oesophagitis. By lowering stomach acidity, it helps relieve symptoms and promotes healing of the gastrointestinal lining.

Lansoprazole works by irreversibly blocking the H+/K+ ATPase proton pump in gastric parietal cells, the final step in acid secretion. This inhibition prevents hydrogen ions from being released into the stomach, leading to a sustained increase in gastric pH and reduced acidity.

The appropriate dose of Lanzul S is determined by the prescribing healthcare professional based on the specific indication, patient age, renal and hepatic function, and other clinical factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for lansoprazole in pregnancy and lactation are limited, and the product’s pregnancy category is listed as unknown. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To order Lanzul S, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lanzul S (lansoprazole) belongs to the proton pump inhibitor (PPI) class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, lansoprazole has a similar efficacy profile but may differ slightly in metabolism and drug‑interaction potential.

Lanzul S should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and excessive heat to maintain its stability and potency.

Lanzul S is taken orally, usually as a whole tablet swallowed with water. It is generally recommended to take the medication before a meal, but patients should follow the specific timing instructions provided by their prescriber.

Serious risks, though uncommon, include severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated diarrhea, and interstitial nephritis. Patients should seek immediate medical attention if they experience symptoms like difficulty breathing, persistent watery diarrhea, or unexplained kidney problems.

Lanzul S should be avoided in individuals with known hypersensitivity to lansoprazole or any component of the formulation. Caution is also advised for patients with severe renal or hepatic impairment, and those taking medications that have major interactions, unless a healthcare professional determines that the benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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