Product image of Lapio (Latanoprost) supplied by GNH India

Lapio

Active Ingredient:
Latanoprost
Origin:
EU

Lapio (Latanoprost)

Latanoprost, the active ingredient in Lapio, is a prostaglandin analog presented as an eye drop for ocular use. It lowers intra‑ocular pressure by increasing uveoscleral outflow and is indicated for the management of open‑angle glaucoma and ocular hypertension in adult patients.

GNH India supplies Lapio as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product complies with EU regulatory standards and is distributed under strict quality‑control procedures. GNH India leverages a global logistics network to ensure timely delivery to qualified healthcare providers.

Manufacturer / TM Owner

Bruschettini S.R.L

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Indications & Clinical Uses

Latanoprost, marketed as Lapio, is used in the prostaglandin analog class to reduce intraocular pressure in specific eye conditions.

  • Open-angle glaucoma: reduces intraocular pressure, helping to preserve visual field and prevent disease progression.
  • Ocular hypertension: lowers intraocular pressure to reduce the risk of developing glaucoma.

How It Works

  • Latanoprost is a synthetic analogue of prostaglandin F2α that binds to FP receptors on the ciliary muscle and scleral tissue. Activation of these receptors remodels extracellular matrix proteins, enhancing uveoscleral outflow of aqueous humor, which leads to a sustained reduction in intraocular pressure.

Side Effects

Latanoprost may cause ocular and peri‑ocular reactions, most of which are mild and reversible.

Common Side Effects

  • Conjunctival hyperemia: redness of the eye due to increased blood flow.
  • Increased eyelash growth: longer, thicker, and darker eyelashes.
  • Iris pigmentation: gradual darkening of the iris, especially in mixed‑color eyes.
  • Eye irritation or foreign‑body sensation.

Serious or Rare Side Effects

  • Uveitis or intraocular inflammation: inflammation inside the eye requiring prompt evaluation.
  • Severe allergic reaction: swelling, itching, or rash that may need medical attention.

Precautions & Warnings

When prescribing Lapio, clinicians should consider several safety and handling measures.

  • Baseline assessment: measure intraocular pressure before initiating therapy.
  • Iris pigmentation: monitor for gradual darkening of the iris, especially in patients with mixed‑color eyes.
  • Eyelash changes: counsel patients about possible increased length and thickness of eyelashes.
  • Ocular surface: avoid use in eyes with active inflammation or infection.
  • Pregnancy and lactation: use only if the potential benefit justifies the potential risk, as safety data are limited.
  • Store at room temperature: keep the bottle in the original packaging, protect from light and moisture.

Avoid Interactions

Latanoprost can interact with other ocular or systemic agents, influencing efficacy or safety.

Major Interactions (Avoid)

  • Concomitant use with other prostaglandin analog eye drops: may cause additive ocular irritation.
  • Recent ocular surgery: increased risk of delayed wound healing; discontinue before surgery.

Moderate Interactions (Monitor Closely)

  • Beta‑blocker eye drops: additive intraocular pressure reduction may lead to hypotony.
  • Systemic carbonic anhydrase inhibitors: monitor intraocular pressure for enhanced effect.
  • Non‑steroidal anti‑inflammatory eye drops: may increase ocular surface irritation.

Frequently Asked Questions

Lapio contains latanoprost and is prescribed to lower intraocular pressure in adults with open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve visual function.

Latanoprost is a prostaglandin F2α analogue that activates FP receptors in the eye, remodeling extracellular matrix and increasing uveoscleral outflow of aqueous humor, which reduces intraocular pressure.

The prescribing clinician determines the dose. Typically, one drop is instilled in the affected eye(s) once daily in the evening, but exact dosing and timing are individualized based on patient response.

Safety data for latanoprost in pregnancy and lactation are limited. It should be used only if the potential benefit outweighs any possible risk to the fetus or infant, and under medical supervision.

To order Lapio, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Latanoprost is often preferred for its once‑daily dosing and strong intraocular pressure‑lowering effect. Compared with beta‑blocker drops such as timolol, it may have fewer systemic side effects but can cause ocular changes like iris darkening. Choice of therapy depends on patient tolerance, comorbidities and physician judgment.

Store Lapio at room temperature, away from direct sunlight and moisture. Keep the bottle in its original packaging, and ensure the cap is tightly closed to maintain sterility. Do not freeze the product.

Wash your hands, tilt the head back, and gently pull down the lower eyelid to form a pocket. Squeeze one drop into the pocket without touching the tip to the eye or lashes. Close the eye gently for a few seconds and avoid blinking excessively. Repeat for the other eye if prescribed.

Serious risks include intraocular inflammation (uveitis) and severe allergic reactions. Patients should seek immediate medical attention if they experience eye pain, redness, vision changes, swelling, or systemic allergic symptoms such as rash or difficulty breathing.

Latanoprost is contraindicated in patients with known hypersensitivity to latanoprost or any component of the formulation, and it should be avoided in eyes with active inflammation, infection, or recent ocular surgery unless directed by an ophthalmologist.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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