Product image of Lapol 30 (Lansoprazole) supplied by GNH India

Lapol 30

Active Ingredient:
Lansoprazole
Origin:
EU

Lapol 30 (Lansoprazole)

Lansoprazole, the active ingredient in Lapol, is a proton pump inhibitor presented as an oral dosage form for oral use. It reduces gastric acid production and is employed in the management of acid‑related gastrointestinal disorders in adults and adolescents.
GNH India supplies Lapol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Confar - Consórcio Farmacêutico Lda

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Indications & Clinical Uses

Lansoprazole acts on the gastric acid secretion pathway and is indicated for several acid‑related conditions.

  • Gastro‑esophageal reflux disease (GERD): provides symptomatic relief and promotes healing of esophageal irritation.
  • Peptic ulcer disease: supports ulcer healing and reduces recurrence risk.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid secretion.
  • Helicobacter pylori eradication therapy: enhances bacterial clearance when used with antibiotics.

How It Works

  • Lansoprazole selectively and irreversibly inhibits the H+/K+ ATPase enzyme (proton pump) located on the secretory surface of gastric parietal cells. By blocking this final step of acid production, it markedly reduces both basal and stimulated gastric acid secretion, leading to an increased gastric pH and facilitating mucosal healing in acid‑related disorders.

Side Effects

Adverse reactions may occur with Lansoprazole therapy.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: watery stools, usually transient.
  • Nausea: occasional upset stomach.
  • Abdominal pain: cramp‑like discomfort.
  • Flatulence: increased gas.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, difficulty breathing.
  • Clostridioides difficile infection: persistent diarrhea, abdominal pain.
  • Liver enzyme elevation: signs of hepatic dysfunction.
  • Low magnesium levels: muscle cramps, irregular heartbeat.
  • Stevens‑Johnson syndrome: severe skin blistering.
  • Pancreatitis: upper abdominal pain, nausea, vomiting.

Precautions & Warnings

Before initiating Lansoprazole, consider the following safety measures.

  • Renal function assessment: adjust use in severe impairment.
  • Hepatic impairment evaluation: monitor for accumulation.
  • Elderly patients: start with lowest effective dose.
  • Concomitant medications: review drugs that require gastric acidity for absorption.
  • Infection monitoring: be alert for signs of C. difficile infection.
  • Store at room temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Lansoprazole may interact with several medicines; awareness helps prevent reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Ketoconazole: markedly decreased antifungal absorption.
  • Atazanavir: reduced antiviral effectiveness.
  • Clarithromycin: increased risk of cardiac arrhythmias.
  • HIV protease inhibitors (e.g., ritonavir): diminished antiviral levels.
  • Warfarin: potential alteration of anticoagulant effect.

Moderate Interactions (Monitor Closely)

  • Clopidogrel: reduced antiplatelet activity.
  • Methotrexate: increased serum concentrations.
  • Digoxin: possible increase in serum levels.
  • Iron supplements: decreased iron absorption.
  • Vitamin B12: potential long‑term deficiency with prolonged use.

Frequently Asked Questions

Lapol contains Lansoprazole, which is prescribed to treat gastro‑esophageal reflux disease, peptic ulcer disease, Zollinger‑Ellison syndrome, and to support Helicobacter pylori eradication regimens. It works by lowering stomach acid, helping to relieve symptoms and promote healing of the gastrointestinal lining.

Lansoprazole blocks the H+/K+ ATPase enzyme, also known as the proton pump, on gastric parietal cells. This inhibition prevents the final step of acid secretion, leading to a sustained increase in gastric pH and reduction of both basal and stimulated acid production.

The specific dose of Lapol is determined by the prescribing clinician based on the patient’s condition, severity, and response to therapy. Healthcare professionals tailor the regimen to achieve optimal acid control while minimizing potential risks.

Safety data for Lansoprazole in pregnancy and lactation are limited. The prescriber should weigh potential benefits against possible risks and consider alternative therapies if appropriate. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss use with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lansoprazole belongs to the proton pump inhibitor class, offering more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, its efficacy is similar, but individual response and drug‑interaction profiles may differ, influencing the choice of therapy.

Lapol should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture, heat and direct sunlight to maintain stability and potency throughout its shelf life.

Lapol is taken orally, usually as a whole tablet with a glass of water. It is generally recommended to swallow the tablet before a meal, unless the prescriber advises otherwise, to ensure optimal absorption and effect.

Serious risks, though uncommon, include severe allergic reactions, Clostridioides difficile‑associated diarrhea, low magnesium levels, liver enzyme abnormalities, and rare skin conditions such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience symptoms like rash, persistent diarrhea, muscle cramps, or jaundice.

Patients with known hypersensitivity to Lansoprazole or any component of the formulation should avoid Lapol. Caution is also advised for individuals with severe liver disease, those taking medications that require an acidic environment for absorption, and patients with a history of C. difficile infection.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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