Product image of Lapol (Lansoprazole) supplied by GNH India

Lapol

Active Ingredient:
Lansoprazole
Origin:
EU

Lapol (Lansoprazole)

Lansoprazole, the active ingredient in Lapol, is a proton pump inhibitor presented as an oral tablet for systemic use. It reduces gastric acid production and is prescribed for conditions such as gastro‑oesophageal reflux disease, peptic ulcer disease and Helicobacter pylori eradication therapy.
GNH India supplies Lapol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Confar - Consórcio Farmacêutico Lda

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Indications & Clinical Uses

Lansoprazole acts on the gastric acid‑secretion pathway and is used for several acid‑related disorders.

  • Gastro‑oesophageal reflux disease (GERD): provides symptomatic relief and promotes healing of esophageal irritation.
  • Peptic ulcer disease: supports ulcer healing by maintaining a less acidic gastric environment.
  • Helicobacter pylori eradication: used in combination regimens to improve bacterial clearance.
  • Erosive esophagitis: reduces acid exposure, allowing mucosal recovery.

How It Works

  • Lansoprazole selectively and irreversibly inhibits the H+/K+ ATPase (proton pump) located on the secretory surface of gastric parietal cells. By blocking this final step of acid secretion, it markedly lowers gastric acidity, facilitating mucosal healing and reducing reflux‑related symptoms.

Side Effects

Lansoprazole may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhoea: watery stools, usually self‑limiting.
  • Nausea: occasional upset stomach.
  • Abdominal pain: cramping or discomfort.
  • Flatulence: increased gas.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Clostridioides difficile infection: persistent diarrhoea with fever.
  • Low magnesium levels: muscle cramps, irregular heartbeat.
  • Bone fracture risk: especially with long‑term use.
  • Liver enzyme elevation: abnormal liver function tests.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess renal function: adjust use if severe impairment is present.
  • Review concomitant medications: potential for interaction with drugs requiring acidic pH.
  • Monitor for infection: prolonged acid suppression may increase gastrointestinal infection risk.
  • Evaluate bone health: consider calcium and vitamin D supplementation for long‑term users.
  • Pregnancy and lactation: use only if clearly needed after risk‑benefit assessment.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture.

Avoid Interactions

Lansoprazole can affect the absorption and metabolism of several medicines.

Major Interactions (Avoid)

  • Antiretroviral protease inhibitors (e.g., atazanavir): reduced efficacy due to increased gastric pH.
  • Antifungal agents (e.g., ketoconazole, itraconazole): markedly decreased absorption.
  • Clopidogrel: diminished antiplatelet effect.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible increase in INR, monitor coagulation.
  • Methotrexate (high dose): reduced clearance, watch for toxicity.
  • Digoxin: altered absorption, check serum levels.

Frequently Asked Questions

Lapol contains lansoprazole, which is prescribed for acid‑related conditions such as gastro‑oesophageal reflux disease, peptic ulcer disease, erosive esophagitis and as part of combination therapy for Helicobacter pylori eradication.

Lansoprazole blocks the H+/K+ ATPase proton pump in gastric parietal cells, preventing the final step of acid secretion. This leads to a sustained decrease in gastric acidity, allowing damaged mucosa to heal and reducing reflux symptoms.

The specific dose and dosing schedule of Lapol are determined by the prescribing clinician based on the patient’s condition, severity and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for lansoprazole in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lansoprazole, the active ingredient in Lapol, belongs to the same class as omeprazole, esomeprazole and pantoprazole. All share a similar mechanism of inhibiting the gastric proton pump, but differences exist in pharmacokinetics, drug‑interaction profiles and dosing convenience, which clinicians consider when selecting therapy.

Lapol should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure the packaging remains tightly closed until use.

Lapol is taken orally, usually with a glass of water. It can be taken with or without food, but consistent timing each day helps maintain steady drug levels. Patients should swallow the tablet whole and not crush or chew it.

Serious adverse events, though rare, include severe allergic reactions, Clostridioides difficile infection, low magnesium levels, and an increased risk of bone fractures with long‑term use. Patients should report any unusual symptoms such as rash, persistent diarrhoea, muscle cramps or signs of fracture promptly.

Lapol is contraindicated in individuals with known hypersensitivity to lansoprazole or any component of the formulation. Caution is advised for patients with severe liver disease, those taking medications that require an acidic gastric environment, and patients with a history of osteoporosis when used long‑term.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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