Product image of Laprosep Komb (Timolol Maleate, Latanoprost) supplied by GNH India

Laprosep Komb

Active Ingredient:
Timolol Maleate, Latanoprost
Origin:
EU

Laprosep Komb (Timolol Maleate, Latanoprost)

Timolol maleate and Latanoprost, the active ingredients in Laprosep Komb, are a beta‑blocker and a prostaglandin analog presented as eye drops for ocular use. They are indicated for lowering intra‑ocular pressure in glaucoma and ocular hypertension.
GNH India supplies Laprosep Komb as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Extractumpharma Co.Ltd.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Laprosep Komb is used in the management of ocular conditions that require intra‑ocular pressure reduction.

  • Primary open‑angle glaucoma: lowers pressure to slow optic nerve damage.
  • Ocular hypertension: reduces elevated pressure to prevent progression to glaucoma.
  • Secondary open‑angle glaucoma: assists in controlling pressure when other causes are present.

How It Works

  • Timolol maleate non‑selectively blocks β‑adrenergic receptors in the ciliary body, decreasing aqueous humor production, while Latanoprost, a prostaglandin F2α analog, remodels the extracellular matrix to enhance uveoscleral outflow, together achieving a synergistic reduction of intra‑ocular pressure.

Side Effects

Common Side Effects

  • Eye irritation or burning sensation: mild discomfort after instillation.
  • Blurred vision: transient visual disturbance.
  • Redness of the eye: conjunctival hyperemia.
  • Itching or foreign body sensation: mild ocular pruritus.
  • Dry eye: reduced tear production.
  • Increased pigmentation of the iris: gradual darkening.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, rash, or difficulty breathing.
  • Acute eye pain: may indicate inflammation.
  • Vision loss: sudden decrease in visual acuity.
  • Increased intra‑ocular pressure: paradoxical rise.
  • Systemic bradycardia or hypotension: due to β‑blockade.
  • Respiratory distress: especially in asthmatic patients.

Precautions & Warnings

Before using Laprosep Komb, consider the following precautions.

  • Pregnancy: safety not established; use only if clearly needed.
  • Breastfeeding: caution as drug may be excreted in milk.
  • Asthma or COPD: β‑blocker may exacerbate bronchospasm.
  • Cardiac conduction disorders: avoid in bradycardia or heart block.
  • Contact lens wear: remove lenses before and wait 15 minutes after dosing.
  • Store at room temperature: keep bottle tightly closed, protect from light and moisture.

Avoid Interactions

When co‑administered with other medicines, monitor for additive effects.

Major Interactions (Avoid)

  • Systemic β‑blockers: may cause excessive bradycardia or hypotension.
  • Other prostaglandin analog eye drops: increase risk of ocular side effects.
  • Sympathomimetic ocular agents (e.g., phenylephrine): may reduce IOP‑lowering efficacy.

Moderate Interactions (Monitor Closely):\n- Topical corticosteroids: may diminish pressure‑lowering effect.

  • Anticholinergic eye drops: could affect tear film stability.
  • Carbonic anhydrase inhibitors: additive IOP reduction may require monitoring.

Frequently Asked Questions

Laprosep Komb is prescribed to lower intra‑ocular pressure in patients with primary open‑angle glaucoma, ocular hypertension, and secondary open‑angle glaucoma, helping to prevent optic nerve damage and preserve vision.

Timolol reduces the production of aqueous humor by blocking β‑adrenergic receptors, while Latanoprost increases the outflow of fluid through the uveoscleral pathway as a prostaglandin analog. Their combined action provides a greater reduction in eye pressure than either agent alone.

The dosing regimen for Laprosep Komb is determined by the prescribing ophthalmologist based on the patient’s condition, response, and tolerance. Typically, one drop is instilled in the affected eye(s) once daily, but the exact schedule should follow the prescriber’s instructions.

Safety data for Laprosep Komb in pregnancy and lactation are limited. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made in consultation with a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Compared with monotherapy, the combination of Timolol and Latanoprost offers dual mechanisms—decreased fluid production and increased outflow—resulting in a more pronounced and consistent intra‑ocular pressure reduction, often allowing patients to avoid multiple separate drops.

Laprosep Komb should be stored at room temperature, below 25 °C, in the original container, protected from light and moisture. Keep the bottle tightly closed when not in use and discard any solution that appears discolored or contaminated.

The product is supplied as sterile eye drops. The patient should wash hands, tilt the head back, pull down the lower eyelid, and place a single drop into the conjunctival sac. Close the eye gently and avoid blinking excessively for a few seconds.

Serious risks include severe allergic reactions, sudden increase in intra‑ocular pressure, significant vision loss, systemic bradycardia or hypotension, and respiratory difficulties in patients with asthma or COPD. Any such symptoms require immediate medical attention.

Patients with known hypersensitivity to Timolol, Latanoprost, or any excipients, those with severe bronchial asthma, chronic obstructive pulmonary disease, sinus bradycardia, second‑ or third‑degree heart block, or uncontrolled heart failure should avoid using Laprosep Komb unless advised otherwise by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.