Product image of Laroscorbine (Ascorbic Acid) supplied by GNH India

Laroscorbine

Active Ingredient:
Ascorbic Acid
Origin:
EU

Laroscorbine (Ascorbic Acid)

Ascorbic Acid, the active ingredient in Laroscorbine, is a vitamin presented as an aqueous solution for intravenous use. It is employed to correct vitamin C deficiency and to support immune function in patients requiring parenteral nutrition or at risk of scurvy.

GNH India supplies Laroscorbine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and oncology units worldwide, adhering to EU GMP standards and providing batch‑tested product for global distribution.

Manufacturer / TM Owner

Bayer Healthcare

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Indications & Clinical Uses

Laroscorbine is used in the management of conditions related to vitamin C deficiency and immune support.

  • Vitamin C deficiency (scurvy): restores normal plasma ascorbate levels and resolves classic scurvy symptoms.
  • Immune support: provides adjunctive antioxidant support to enhance immune cell function during acute illness.
  • Parenteral nutrition: supplies essential vitamin C to patients unable to receive oral nutrition, ensuring adequate micronutrient intake.

How It Works

  • Ascorbic Acid acts as an essential cofactor for several enzymatic reactions, including collagen hydroxylation, catecholamine synthesis, and peptide hormone processing. It functions as a potent antioxidant, scavenging free radicals and regenerating other antioxidants, thereby supporting collagen formation, endothelial integrity, and immune cell activity. Intravenous administration bypasses gastrointestinal absorption, rapidly increasing plasma concentrations to achieve therapeutic effects.

Side Effects

Adverse reactions to intravenous ascorbic acid are generally infrequent but may occur.

Common Side Effects

  • Infusion site irritation or pain.
  • Mild nausea or vomiting.
  • Transient headache or flushing.
  • Temporary hypotension during infusion.

Serious or Rare Side Effects

  • Oxalate nephropathy leading to renal impairment.
  • Hemolysis in patients with glucose‑6‑phosphate dehydrogenase (G6PD) deficiency.
  • Anaphylactic or severe allergic reactions.
  • Severe hypotension requiring medical intervention.
  • Acute renal failure in susceptible individuals.

Precautions & Warnings

When using Laroscorbine, consider the following safety measures.

  • Assess renal function: monitor serum creatinine before and during therapy.
  • Screen for G6PD deficiency: avoid use in deficient patients.
  • Avoid concurrent high‑dose calcium: may increase risk of precipitation.
  • Monitor blood pressure: watch for hypotension during infusion.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Laroscorbine may interact with other medicines; awareness of potential interactions is important.

Major Interactions (Avoid)

  • Concurrent oxalate‑producing agents (e.g., ethylene glycol): increase risk of renal oxalate deposition.
  • High‑dose chemotherapy agents that generate free radicals: possible antagonistic effect.
  • Certain point‑of‑care glucose meters: high vitamin C can cause falsely low glucose readings.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: may increase urinary excretion of vitamin C, altering plasma levels.
  • Iron supplements: enhanced iron absorption may lead to overload in susceptible patients.
  • Anticoagulants (e.g., warfarin): high vitamin C intake may potentiate anticoagulant effect.

Frequently Asked Questions

Laroscorbine is an intravenous formulation of ascorbic acid used to treat vitamin C deficiency (scurvy) and to provide adjunctive antioxidant support for the immune system, particularly in patients receiving parenteral nutrition or those at risk of oxidative stress.

Ascorbic acid serves as a cofactor for enzymes involved in collagen synthesis, neurotransmitter production, and hormone metabolism. It also acts as a potent antioxidant, neutralizing free radicals, regenerating other antioxidants, and supporting immune cell function, which together help maintain tissue integrity and host defenses.

The appropriate dose of Laroscorbine is determined by the prescribing clinician based on the patient’s clinical condition, weight, renal function, and therapeutic goals. Dosage regimens are individualized and should follow the prescriber’s instructions.

Safety data for intravenous ascorbic acid in pregnancy and lactation are limited. Clinicians should weigh potential benefits against unknown risks and consider alternative therapies when possible. Pregnant or nursing patients should only use Laroscorbine if clearly indicated by a healthcare professional.

To order Laroscorbine, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling if needed), and necessary import documentation.

Laroscorbine is a pharmaceutical‑grade intravenous ascorbic acid, offering higher purity and controlled sterility compared with oral supplements. Intravenous delivery achieves much higher plasma concentrations rapidly, which can be advantageous in acute deficiency or when oral absorption is compromised, whereas oral products provide lower, more gradual increases.

Laroscorbine should be stored at 2‑8 °C, protected from light, and kept in its original container. Do not freeze or shake the product. Before use, inspect for particulate matter or discoloration and follow aseptic techniques for preparation and administration.

Laroscorbine is administered intravenously by a qualified healthcare professional. The solution is typically infused over a prescribed period, often using an infusion pump or controlled drip, to ensure safe delivery and to monitor for any infusion‑related reactions.

Serious risks include oxalate nephropathy leading to renal impairment, hemolysis in patients with G6PD deficiency, severe allergic reactions such as anaphylaxis, and profound hypotension during infusion. Patients should be monitored closely for these events, especially those with pre‑existing kidney disease or enzyme deficiencies.

Laroscorbine should be avoided in individuals with known G6PD deficiency, severe renal impairment, or a history of hypersensitivity to ascorbic acid or any component of the formulation. It is also contraindicated in patients receiving medications that may precipitate oxalate formation without appropriate monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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