Product image of Lasa (Famotidine) supplied by GNH India

Lasa

Active Ingredient:
Famotidine
Origin:
EU

Lasa (Famotidine)

Famotidine, the active ingredient in Lasa, is a histamine H2 receptor antagonist presented as an oral dosage form for oral use. It reduces gastric acid secretion and is used to treat conditions such as gastro‑oesophageal reflux disease, peptic ulcer disease and to prevent NSAID‑induced ulcers.

GNH India supplies Lasa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aristo Pharma Iberia, S.L.

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Indications & Clinical Uses

Famotidine acts on the histamine H2 receptors that regulate gastric acid production, making it useful for several acid‑related gastrointestinal conditions.

  • Gastro‑oesophageal reflux disease (GERD): alleviates heartburn and acid reflux symptoms.
  • Peptic ulcer disease: promotes healing of gastric and duodenal ulcers.
  • Erosive esophagitis: aids recovery of inflamed esophageal lining.
  • Prevention of NSAID‑induced ulcers: reduces the risk of ulcer formation in patients taking non‑steroidal anti‑inflammatory drugs.

How It Works

  • Famotidine competitively and reversibly binds to histamine H2 receptors on gastric parietal cells, inhibiting the action of histamine. This blockade decreases cyclic AMP formation, leading to reduced activity of the proton pump and consequently lower gastric acid secretion, helping to restore the normal pH balance in the gastrointestinal tract.

Side Effects

Famotidine is generally well tolerated, but some patients may experience adverse reactions.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: loose stools that resolve with continued use.
  • Nausea: occasional upset stomach.
  • Dizziness: transient light‑headedness.
  • Fatigue: feeling unusually tired.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Hepatic dysfunction: signs of liver injury such as jaundice.
  • Cardiac arrhythmias: irregular heartbeats in susceptible individuals.

Precautions & Warnings

Before using Lasa, consider the following safety measures.

  • Renal impairment: dose adjustment may be required in patients with reduced kidney function.
  • Elderly patients: monitor for confusion or dizziness, as sensitivity may be increased.
  • Concomitant medications: review all current drugs for potential interactions.
  • Pregnancy and breastfeeding: use only if the potential benefit justifies the potential risk.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Famotidine may interact with several medicines; awareness helps avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: can markedly decrease famotidine absorption.
  • Cimetidine: may raise famotidine plasma concentrations, increasing risk of side effects.

Moderate Interactions (Monitor Closely)

  • Warfarin: famotidine may enhance anticoagulant effect, requiring INR monitoring.
  • Theophylline: possible increase in theophylline levels, necessitating dose review.
  • Ketoconazole: reduced ketoconazole absorption may diminish its antifungal efficacy.

Frequently Asked Questions

Lasa contains famotidine, which is used to treat gastro‑oesophageal reflux disease, peptic ulcer disease, erosive esophagitis, and to prevent ulcers that can develop from regular use of NSAIDs. It works by lowering stomach acid, helping to relieve symptoms and promote healing.

Famotidine blocks histamine H2 receptors on the stomach’s parietal cells. By preventing histamine from activating these receptors, the drug reduces the production of cyclic AMP, which in turn lowers the activity of the proton pump responsible for secreting gastric acid.

The appropriate dose of Lasa is determined by a qualified healthcare professional based on the individual’s condition, age, renal function and other factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Famotidine is classified as a pregnancy category that should be used only if the potential benefit outweighs any possible risk to the fetus. Breastfeeding mothers should consult their doctor, as the drug does pass into breast milk in small amounts.

To request Lasa, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Famotidine belongs to the H2‑receptor antagonist class, offering a rapid onset and fewer drug‑interaction concerns compared with proton‑pump inhibitors. It is generally effective for mild‑to‑moderate acid‑related conditions and is available over the counter, whereas some alternatives require prescription and may have a higher incidence of certain side effects.

Lasa should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight and strong odors to maintain its stability and potency throughout its shelf life.

Lasa is taken orally, usually with a glass of water. It can be taken with or without food, but patients should follow the specific instructions given by their prescriber to ensure optimal absorption and effectiveness.

Serious but rare risks include severe allergic reactions such as anaphylaxis, liver injury, and cardiac arrhythmias. Patients should seek immediate medical attention if they experience symptoms like rash, swelling, jaundice, or irregular heartbeats while using the medication.

Individuals with known hypersensitivity to famotidine or any other H2‑receptor antagonist should avoid Lasa. Patients with severe renal impairment should consult their physician, as dose adjustments may be necessary, and it should be used cautiously in pregnant or breastfeeding women.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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