Product image of Lasca (Dienogest, Ethinylestradiol) supplied by GNH India

Lasca

Active Ingredient:
Dienogest, Ethinylestradiol
Origin:
EU

Lasca (Dienogest, Ethinylestradiol)

Dienogest/Ethinylestradiol, the active ingredients in Lasca, are a combined oral contraceptive presented as an oral tablet for oral use. It prevents pregnancy in women of reproductive age by inhibiting ovulation and altering cervical mucus and endometrial lining.

GNH India supplies Lasca as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Uab Exeltis Baltics

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Indications & Clinical Uses

  • Lasca, a combined oral contraceptive, is used within the hormonal contraceptive pathway to prevent pregnancy.
  • Prevention of pregnancy: provides effective birth control for women of childbearing age.
  • Regulation of menstrual bleeding: helps achieve more predictable bleeding patterns in women using hormonal contraception.

How It Works

  • Dienogest and ethinylestradiol act together to suppress the mid‑cycle surge of luteinising hormone (LH) and follicle‑stimulating hormone (FSH), thereby inhibiting ovulation. The estrogen component stabilises the endometrial lining, while the progestogen component thickens cervical mucus and induces endometrial changes that reduce the likelihood of implantation.

Side Effects

Lasca may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nausea
  • Breast tenderness
  • Headache
  • Weight gain or fluid retention
  • Mood changes
  • Breakthrough or spotting bleeding

Serious or Rare Side Effects

  • Venous thromboembolism (deep‑vein thrombosis, pulmonary embolism)
  • Arterial thrombosis (stroke, myocardial infarction)
  • Hypertension or worsening of existing high blood pressure
  • Liver dysfunction or cholestasis
  • Severe allergic reactions (anaphylaxis, angioedema)
  • Visual disturbances or ocular migraines

Precautions & Warnings

Before prescribing Lasca, clinicians should evaluate individual risk factors and counsel patients on safe use.

  • Assess cardiovascular risk: review history of thromboembolism, hypertension, or smoking.
  • Avoid smoking: especially in women over 35 years of age.
  • Monitor blood pressure: contraceptives may increase systolic or diastolic pressure.
  • Consider liver function: hepatic impairment can alter hormone metabolism.
  • Store at ambient temperature: keep below 25°C, protect from moisture and light.

Avoid Interactions

Lasca can interact with several medication classes, altering its effectiveness or safety profile.

Major Interactions (Avoid)

  • Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin) may reduce contraceptive efficacy.
  • Strong CYP3A4 inhibitors (e.g., ritonavir, ketoconazole) may increase hormone levels and risk of side effects.
  • Concurrent use with other estrogen‑containing products (e.g., hormone replacement therapy) may raise thrombotic risk.

Moderate Interactions (Monitor Closely)

  • Rifampin and other potent antibiotics can lower effectiveness.
  • St. John’s wort and similar herbal supplements may decrease plasma concentrations.
  • Certain SSRIs may potentiate mood‑related side effects.

Frequently Asked Questions

Lasca is a combined oral contraceptive containing dienogest and ethinylestradiol. It is prescribed to prevent pregnancy in women of reproductive age by inhibiting ovulation and creating cervical mucus and endometrial conditions that are unfavorable for fertilisation and implantation.

The ethinylestradiol component provides estrogenic activity that stabilises the endometrial lining, while dienogest, a progestogen, suppresses the mid‑cycle surge of luteinising hormone (LH) and follicle‑stimulating hormone (FSH). This dual action blocks ovulation and alters cervical mucus and the uterine lining, reducing the chance of fertilisation and implantation.

The dosing regimen is determined by the prescribing clinician. Typically, Lasca is taken as one tablet daily for a set number of days followed by a pill‑free interval, but the exact schedule and any variations are individualized based on the patient’s medical history and the prescriber’s judgment.

Lasca is not intended for use during pregnancy and should be discontinued if pregnancy occurs. Limited safety data exist for breastfeeding; generally, combined oral contraceptives are not recommended for nursing mothers unless the benefits outweigh potential risks, and the prescriber should evaluate each case.

To order Lasca, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Lasca offers efficacy comparable to other combined oral contraceptives. Its progestogen component, dienogest, has lower androgenic activity than some older progestins, which may result in a more favourable side‑effect profile for acne or lipid metabolism, while still providing reliable contraception.

Store Lasca tablets at ambient temperature, preferably below 25 °C. Keep the product in its original blister pack or container, protect it from moisture and direct light, and ensure the packaging remains sealed until use to maintain potency.

Lasca is taken orally as a tablet with water. It is usually recommended to take the tablet at the same time each day to maintain consistent hormone levels, and patients should follow the schedule prescribed by their healthcare professional.

The most serious risks include venous or arterial thromboembolic events such as deep‑vein thrombosis, pulmonary embolism, stroke, or myocardial infarction. Additional concerns are severe hypertension, liver disorders, and rare but potentially life‑threatening allergic reactions. Patients should seek immediate medical attention if they experience symptoms suggestive of these conditions.

Lasca is contraindicated in women with a history of thromboembolic disease, uncontrolled hypertension, known estrogen‑dependent tumours, severe liver disease, or those who smoke cigarettes and are over 35 years of age. It should also be avoided in individuals with known hypersensitivity to dienogest, ethinylestradiol, or any excipients in the tablet.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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