Product image of Lasilix Special (Furosemide) supplied by GNH India

Lasilix Special

Active Ingredient:
Furosemide
Origin:
EU

Lasilix Special (Furosemide)

Furosemide, the active ingredient in Lasilix Special, is a loop diuretic presented as an oral tablet for oral use. It treats edema associated with heart failure, liver cirrhosis, renal disease, and hypertension in adult patients.

GNH India supplies Lasilix Special as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sanofi Winthrop Industrie

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Indications & Clinical Uses

Lasilix Special, a loop diuretic, is used to manage conditions characterized by fluid overload.

  • Edema associated with heart failure: reduces excess fluid and improves breathing.
  • Edema associated with liver cirrhosis: promotes diuresis to lessen abdominal swelling.
  • Edema associated with renal disease: helps eliminate retained water and salts.
  • Hypertension: lowers blood pressure by decreasing plasma volume.

How It Works

  • Furosemide inhibits the Na+/K+/2Cl‑ cotransporter in the thick ascending limb of the loop of Henle, blocking reabsorption of sodium, chloride, and potassium. This disruption increases urinary excretion of these electrolytes together with water, leading to a rapid diuretic effect and reduction of extracellular fluid volume.

Side Effects

Furosemide may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Increased urination: frequent need to void.
  • Electrolyte disturbances: low potassium or sodium levels.
  • Dizziness or light‑headedness, especially on standing.
  • Headache.
  • Dehydration: dry mouth, thirst.
  • Blurred vision.

Serious or Rare Side Effects

  • Ototoxicity: hearing loss or ringing in the ears.
  • Severe dehydration leading to hypotension.
  • Allergic reactions: rash, itching, swelling.
  • Acute kidney injury or worsening renal function.
  • Severe electrolyte imbalance such as hypokalemia.
  • Blood dyscrasias: neutropenia or thrombocytopenia.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Monitor electrolytes: check serum potassium and sodium regularly.
  • Assess renal function: evaluate creatinine and eGFR before and during treatment.
  • Adjust dose in hepatic impairment: use lower doses if liver function is compromised.
  • Use caution in hypotension: avoid rapid volume depletion.
  • Avoid use in anuria: contraindicated when no urine output.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Furosemide can interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • NSAIDs: may blunt diuretic response.
  • Aminoglycoside antibiotics: increase risk of ototoxicity.
  • Lithium: can raise lithium levels, risking toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may cause excessive blood pressure reduction.
  • Thiazide diuretics: combined use can intensify electrolyte loss.

Frequently Asked Questions

Lasilix Special contains furosemide, a loop diuretic prescribed to reduce fluid accumulation in patients with edema caused by heart failure, liver cirrhosis, or renal disease, and to lower high blood pressure when fluid overload contributes to hypertension.

Furosemide blocks the Na+/K+/2Cl‑ cotransporter in the thick ascending limb of the loop of Henle, preventing reabsorption of sodium, chloride, and potassium. This leads to increased urinary excretion of these ions together with water, decreasing extracellular fluid volume and blood pressure.

The appropriate dose of Lasilix Special is determined by the prescribing clinician based on the patient’s medical condition, severity of fluid overload, kidney function, and response to therapy. Dosage adjustments are made individually and should follow the prescriber’s instructions.

The safety of furosemide in pregnancy and lactation has not been definitively established. It should be used only if clearly needed and after a risk‑benefit assessment by the healthcare provider. Breastfeeding mothers should discuss potential effects with their clinician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Furosemide is a potent loop diuretic, producing a faster and greater diuretic effect than thiazide diuretics, which act on the distal tubule. Compared with other loop diuretics such as bumetanide, furosemide has a similar efficacy but may differ in dosing frequency and potency per milligram.

Lasilix Special should be stored at room temperature, below 25 °C, in its original packaging. Keep the tablets away from moisture and direct sunlight to maintain stability and potency throughout the shelf life.

Lasilix Special is taken orally, usually with a full glass of water. It may be taken with or without food, but patients should follow the prescriber’s guidance on timing relative to meals to optimize absorption and reduce gastrointestinal discomfort.

The most serious risks include severe electrolyte disturbances (especially low potassium), dehydration leading to hypotension, ototoxicity (hearing loss or ringing), and acute kidney injury. Patients should be monitored regularly for these complications, especially during the initial treatment phase.

Lasilix Special is contraindicated in patients with anuria (no urine output), known hypersensitivity to furosemide or other sulfonamide drugs, and in those with severe electrolyte imbalance that cannot be corrected. Caution is also advised for patients with severe hepatic or renal impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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