Product image of Lasix Fiale (Furosemide) supplied by GNH India

Lasix Fiale

Active Ingredient:
Furosemide
Origin:
EU

Lasix Fiale (Furosemide)

Furosemide, the active ingredient in Lasix Fiale, is a loop diuretic presented as an injectable solution for intramuscular or intravenous use. It is employed to manage fluid overload and hypertension in patients with heart, liver, or kidney conditions.
GNH India supplies Lasix Fiale as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sanofi-Aventis Deutschland Gmbh

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Indications & Clinical Uses

Lasix Fiale, a loop diuretic, is used to treat conditions characterized by excess fluid accumulation or elevated blood pressure.

  • Heart failure‑related edema: promotes removal of excess fluid, relieving swelling and breathlessness.
  • Liver cirrhosis‑associated edema: reduces ascites and peripheral edema by increasing urinary output.
  • Renal disease‑related edema: assists in fluid removal when kidney function is impaired.
  • Hypertension: lowers blood pressure by decreasing plasma volume through enhanced diuresis.

How It Works

  • Furosemide inhibits the Na+/K+/2Cl‑ cotransporter located in the thick ascending limb of the loop of Henle. This blockade reduces reabsorption of sodium, chloride, and potassium, leading to increased excretion of these ions together with water, thereby decreasing extracellular fluid volume and lowering blood pressure.

Side Effects

Adverse reactions may occur with Lasix Fiale administration.

Common Side Effects

  • Dizziness or light‑headedness
  • Headache
  • Electrolyte disturbances (e.g., low potassium or sodium)
  • Dehydration or increased thirst

Serious or Rare Side Effects

  • Ototoxicity (hearing loss or ringing)
  • Severe allergic reactions (anaphylaxis, skin rash)
  • Acute kidney injury or worsening renal function

Precautions & Warnings

When using Lasix Fiale, clinicians should observe several safety measures.

  • Monitor electrolytes: check serum potassium, sodium, and magnesium regularly.
  • Assess renal function: evaluate creatinine and urine output before and during therapy.
  • Adjust dose in hepatic impairment: reduce dosage if liver disease is present.
  • Use caution in hypotension: avoid rapid volume depletion in patients with low blood pressure.
  • Avoid in anuria: do not administer if the patient produces no urine.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Furosemide can interact with several medications, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • NSAIDs: may blunt diuretic effect and increase renal risk.
  • Aminoglycoside antibiotics: heightened risk of ototoxicity.
  • Lithium: furosemide can raise lithium levels, leading to toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may cause excessive blood pressure reduction.
  • Digoxin: electrolyte shifts can predispose to digoxin toxicity.
  • Other antihypertensives: monitor for additive hypotensive effects.

Frequently Asked Questions

Lasix Fiale is indicated for the management of edema associated with heart failure, liver cirrhosis, and renal disease, as well as for the treatment of hypertension. It helps remove excess fluid by increasing urine output, thereby reducing swelling and lowering blood pressure.

Furosemide acts on the thick ascending limb of the loop of Henle, where it blocks the Na+/K+/2Cl‑ cotransporter. This inhibition prevents reabsorption of sodium, chloride, and potassium, leading to increased excretion of these ions together with water, which reduces extracellular fluid volume.

The specific dose of Lasix Fiale is determined by the prescribing clinician based on the patient’s condition, severity of edema, renal function, and response to therapy. Dosage adjustments are individualized and should follow the prescriber’s instructions.

The safety of Lasix Fiale in pregnancy and lactation has not been definitively established. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Lasix Fiale (furosemide) is a loop diuretic, which is generally more potent than thiazide or potassium‑sparing diuretics for rapid fluid removal. It is preferred in acute settings such as severe edema or hypertensive emergencies, whereas other classes may be used for chronic, milder fluid management.

Lasix Fiale should be stored at 2‑8 °C (refrigerated), protected from light, and must not be frozen or shaken. Maintaining the cold chain preserves the stability and sterility of the injectable solution.

Lasix Fiale is administered by a healthcare professional via intramuscular or intravenous injection. The route, rate of infusion, and volume depend on the clinical situation and the prescriber’s orders.

Serious risks include ototoxicity (potential hearing loss), severe electrolyte imbalances such as hypokalemia or hyponatremia, acute kidney injury, and hypersensitivity reactions. Patients should be monitored closely for these complications, especially during high‑dose or prolonged therapy.

Lasix Fiale is contraindicated in patients with anuria (no urine output) and in those with known hypersensitivity to furosemide or other sulfonamide-derived drugs. Caution is also advised in individuals with severe hepatic impairment or uncontrolled electrolyte disturbances.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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