Product image of Lasix Retard (Furosemide) supplied by GNH India

Lasix Retard

Active Ingredient:
Furosemide
Origin:
EU

Lasix Retard (Furosemide)

Furosemide, the active ingredient in Lasix Retard, is a loop diuretic presented as an oral tablet for oral use. It treats edema associated with congestive heart failure, liver cirrhosis, renal disease, and hypertension in adult patients. Lasix Retard is manufactured in the European Union and complies with international quality standards.

GNH India supplies Lasix Retard as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sanofi-Aventis Norge As

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Indications & Clinical Uses

Lasix Retard is a loop diuretic that reduces fluid overload in several clinical conditions.

  • Edema associated with congestive heart failure: helps remove excess fluid and improve symptoms.
  • Edema due to liver cirrhosis: promotes diuresis to alleviate abdominal swelling.
  • Edema in renal disease (nephrotic syndrome): increases urinary output to manage fluid retention.
  • Hypertension: lowers blood pressure by decreasing plasma volume.

How It Works

  • Furosemide inhibits the Na⁺‑K⁺‑2Cl⁻ symporter located in the thick ascending limb of the loop of Henle. This blockade reduces reabsorption of sodium, chloride, and potassium, leading to increased excretion of these electrolytes together with water. The resulting diuresis decreases extracellular fluid volume, which helps relieve edema and lower blood pressure.

Side Effects

Lasix Retard may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Increased urinary frequency: more frequent need to void.
  • Electrolyte imbalance (especially low potassium): may cause muscle cramps or weakness.
  • Dizziness or light‑headedness: often related to volume depletion.
  • Headache: can accompany changes in blood pressure.
  • Blurred vision: occasional transient visual disturbances.

Serious or Rare Side Effects

  • Severe dehydration: can lead to hypotension and renal impairment.
  • Ototoxicity (hearing loss or tinnitus): associated with high doses or rapid infusion.
  • Acute kidney injury: marked rise in serum creatinine.
  • Allergic reactions: rash, itching, or anaphylaxis.
  • Life‑threatening electrolyte disturbances (e.g., hyponatremia, hypokalemia).

Precautions & Warnings

Before initiating therapy with Lasix Retard, several safety considerations are recommended.

  • Monitor electrolytes: regular checks of sodium, potassium, and chloride levels.
  • Assess renal function: evaluate serum creatinine and eGFR periodically.
  • Use caution in hypotension: avoid rapid volume depletion.
  • Avoid in anuria: the drug is ineffective when urine output is absent.
  • Adjust dose in hepatic impairment: liver disease may alter drug handling.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Lasix Retard can interact with other medicines, affecting efficacy or safety.

Major Interactions (Avoid)

  • NSAIDs (e.g., ibuprofen): may blunt diuretic response.
  • Aminoglycoside antibiotics (e.g., gentamicin): increase risk of ototoxicity.
  • Lithium: can raise lithium serum concentrations and toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may enhance hypotensive effect.
  • Other antihypertensives: additive blood pressure lowering.
  • Corticosteroids: can exacerbate fluid loss and electrolyte disturbances.

Frequently Asked Questions

Lasix Retard is a prescription‑only oral tablet containing furosemide. It is used to treat fluid overload conditions such as edema caused by congestive heart failure, liver cirrhosis, or renal disease, and it is also employed to lower high blood pressure in adults.

Furosemide acts on the thick ascending limb of the loop of Henle in the kidney, where it blocks the Na⁺‑K⁺‑2Cl⁻ cotransporter. This inhibition prevents reabsorption of sodium, chloride, and potassium, leading to increased urinary excretion of these ions together with water, thereby reducing extracellular fluid volume.

The appropriate dose of Lasix Retard is determined by the prescribing clinician based on the individual’s medical condition, severity of fluid retention, renal function, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose without medical advice.

The safety of Lasix Retard during pregnancy and lactation has not been definitively established. It should only be used if the potential benefit justifies the possible risk to the fetus or infant, and this decision must be made by a qualified healthcare professional.

To order Lasix Retard, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Lasix Retard contains furosemide, which is the most widely used loop diuretic. Compared with other agents such as bumetanide or torsemide, furosemide has a well‑characterized efficacy and safety profile, but individual response and side‑effect tolerance may vary, making clinician selection important.

Store Lasix Retard at room temperature, preferably below 25 °C. Keep the tablets in the original packaging to protect them from moisture and light. Do not store in bathrooms or near heat sources, and keep out of reach of children.

Lasix Retard is taken orally, usually with a full glass of water. It may be taken with or without food, but patients should follow the prescriber’s guidance regarding timing relative to meals to minimize gastrointestinal discomfort.

Serious risks include severe dehydration, marked electrolyte disturbances (especially low potassium or sodium), ototoxicity leading to hearing loss, acute kidney injury, and life‑threatening hypotension. Patients should report symptoms such as faintness, rapid weight loss, hearing changes, or muscle weakness promptly.

Lasix Retard should be avoided in patients with anuria (no urine output), severe hypersensitivity to furosemide or other sulfonamides, and in those with uncontrolled electrolyte imbalances. Caution is also advised for individuals with severe liver disease, hypotension, or renal impairment, pending medical evaluation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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