Product image of Lasonil Antinfiammatorio E Antireumatico (Naproxen Sodium) supplied by GNH India

Lasonil Antinfiammatorio E Antireumatico

Active Ingredient:
Naproxen Sodium
Origin:
EU

Lasonil Antinfiammatorio E Antireumatico (Naproxen Sodium)

Naproxen sodium, the active ingredient in Lasonil Antinfiammatorio E Antireumatico, is a nonsteroidal anti‑inflammatory drug presented as an oral tablet for oral use. It treats pain, inflammation and rheumatic conditions in adults.
GNH India supplies Lasonil Antinfiammatorio E Antireumatico as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bayer Spa

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Indications & Clinical Uses

Naproxen sodium is an NSAID that reduces inflammation and pain in several musculoskeletal and rheumatic disorders.

  • Pain: provides analgesic relief for acute and chronic pain conditions.
  • Inflammation: decreases inflammatory response in affected tissues.
  • Rheumatoid arthritis: improves joint symptoms and functional ability.
  • Osteoarthritis: reduces joint pain and stiffness.
  • Musculoskeletal disorders: alleviates discomfort associated with sprains, strains and back pain.

How It Works

  • Naproxen sodium reversibly inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, blocking the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin synthesis diminishes inflammation, lowers pain signaling, and limits fever generation at sites of tissue injury.

Side Effects

Naproxen sodium may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Gastrointestinal discomfort or dyspepsia.
  • Headache.
  • Dizziness.
  • Nausea.
  • Mild skin rash.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Cardiovascular events such as myocardial infarction or stroke.
  • Severe cutaneous reactions (e.g., Stevens‑Johnson syndrome).
  • Elevated liver enzymes or hepatitis.
  • Acute kidney injury or worsening of chronic renal disease.

Precautions & Warnings

Before initiating therapy, consider patient‑specific risk factors and monitor appropriately.

  • Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding.
  • Evaluate cardiovascular history: use cautiously in those with heart disease or stroke risk.
  • Monitor renal function: adjust or discontinue if creatinine rises.
  • Use the lowest effective dose for the shortest duration needed.
  • Avoid in individuals with known hypersensitivity to naproxen or other NSAIDs.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Naproxen sodium can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding potential.

Moderate Interactions (Monitor Closely):\n- ACE inhibitors or ARBs: possible reduction in renal function.

  • Diuretics: may enhance nephrotoxic effects.
  • Lithium: naproxen can raise lithium serum levels.

Frequently Asked Questions

Lasonil Antinfiammatorio E Antireumatico contains naproxen sodium, an NSAID indicated for the relief of mild to moderate pain, reduction of inflammation, and management of rheumatic disorders such as rheumatoid arthritis and osteoarthritis. It is commonly prescribed for musculoskeletal pain, joint stiffness, and inflammatory conditions.

Naproxen sodium blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. By lowering prostaglandin levels, the drug reduces the inflammatory response, diminishes pain signaling, and helps control fever, providing symptomatic relief in affected tissues.

The appropriate dose of Lasonil Antinfiammatorio E Antireumatico is determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and overall health status. Patients should follow the prescriber’s instructions and not adjust the dose without medical guidance.

Naproxen sodium is generally classified as a pregnancy category that requires caution, especially in the third trimester, due to potential risks to the fetus. It is excreted in breast milk, so breastfeeding mothers should consult their physician before use. Professional medical advice is essential to weigh benefits against risks.

To place an order, visit the product page on gnhindia.com, submit an enquiry with the required quantity, and provide institutional or trade credentials. GNH India’s team will verify eligibility, then respond with pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Both naproxen sodium (Lasonil) and ibuprofen belong to the NSAID class and share similar mechanisms of COX inhibition. Naproxen generally has a longer half‑life, allowing less frequent dosing, while ibuprofen may have a quicker onset. Choice between them depends on clinical factors, patient tolerance, and physician preference.

Lasonil should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments.

Lasonil is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce gastrointestinal discomfort. Patients should swallow the tablet whole and not crush or chew it unless directed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, cardiovascular events such as heart attack or stroke, severe skin reactions, liver injury, and acute kidney damage. Patients experiencing signs of these conditions should seek immediate medical attention.

Individuals with a known hypersensitivity to naproxen, other NSAIDs, or any component of the formulation should avoid it. It is also contraindicated in patients with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or significant renal impairment unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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