Product image of Lastin (Azelastine Hydrochloride) supplied by GNH India

Lastin

Active Ingredient:
Azelastine Hydrochloride
Origin:
EU

Lastin (Azelastine Hydrochloride)

Azelastine Hydrochloride, the active ingredient in Lastin, is an antihistamine presented as a nasal spray for nasal use. It treats allergic rhinitis (seasonal and perennial) and hay fever in adults and children.

GNH India supplies Lastin as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Viatris Aps

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Lastin, an antihistamine nasal spray, acts on the histamine pathway to relieve symptoms of allergic airway disease.
  • Allergic rhinitis (seasonal): reduces nasal congestion, itching, sneezing and rhinorrhea.
  • Allergic rhinitis (perennial): provides consistent relief of chronic nasal allergy symptoms.
  • Hay fever: alleviates typical hay‑fever nasal complaints such as watery eyes and runny nose.

How It Works

  • Azelastine hydrochloride selectively blocks H1‑histamine receptors in the nasal mucosa, preventing histamine‑induced vasodilation, increased vascular permeability and sensory nerve activation. It also exhibits anti‑inflammatory activity by inhibiting the release of inflammatory mediators, thereby reducing nasal edema and irritation associated with allergic reactions.

Side Effects

Common Side Effects

  • Nasal irritation or burning sensation.
  • Bitter taste after administration.
  • Headache.
  • Drowsiness or mild fatigue.
  • Throat irritation.
  • Sneezing.

Serious or Rare Side Effects

  • Epistaxis (nosebleed).
  • Severe allergic reaction such as anaphylaxis.
  • Nasal ulceration or crusting.
  • Vision changes or ocular irritation.

Precautions & Warnings

  • Before using Lastin, consider the following precautions.
  • Pregnancy: consult a healthcare professional as safety data are limited.
  • Breastfeeding: use with caution; limited information is available.
  • Concomitant CNS depressants: may increase drowsiness.
  • Use in children: follow pediatric dosing guidance.
  • Avoid spray into eyes: may cause irritation.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Azelastine may interact with other substances; monitor the following.

Major Interactions (Avoid)

  • Alcohol: additive sedative effect.
  • Other antihistamines: risk of excessive anticholinergic load.

Moderate Interactions (Monitor Closely)

  • CYP450 inhibitors or inducers: may alter azelastine metabolism.
  • Beta‑blockers: may mask symptoms of severe allergic reactions.
  • Nasal decongestants: may increase local irritation when used together.

Frequently Asked Questions

Lastin is an over‑the‑counter nasal spray containing azelastine hydrochloride. It is indicated for the relief of symptoms associated with allergic rhinitis, including seasonal and perennial forms, as well as hay fever. The spray helps reduce nasal congestion, itching, sneezing, and runny nose.

Azelastine hydrochloride works by selectively blocking H1‑histamine receptors in the nasal mucosa, preventing histamine‑mediated inflammation and sensory nerve activation. This antagonism reduces vasodilation, vascular permeability, and the release of inflammatory mediators, leading to decreased nasal swelling and irritation.

The dosing regimen for Lastin is determined by a qualified prescriber based on the patient’s age, severity of symptoms, and clinical response. Typically, one or two sprays per nostril are used, but the exact number and frequency should follow the healthcare professional’s instructions.

Safety data for azelastine hydrochloride in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Lastin.

To order Lastin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Lastin contains azelastine, a second‑generation antihistamine with both antihistaminic and anti‑inflammatory properties. Compared with first‑generation sprays, azelastine generally causes less sedation. Its rapid onset and dual action often provide quicker symptom relief than some older agents, while maintaining a favorable safety profile.

Lastin should be stored at room temperature, away from direct sunlight and excessive heat. Keep the spray in its original packaging to protect it from moisture. Do not freeze the product, and ensure the nozzle is clean and free of debris before each use.

Lastin is administered as a nasal spray. The user gently inserts the tip into one nostril, closes the opposite nostril, and sprays the prescribed number of actuations while breathing in gently. The process is repeated in the other nostril if required, following the prescriber’s directions.

While most users experience only mild side effects, serious risks include nosebleeds (epistaxis), severe allergic reactions such as anaphylaxis, and nasal ulceration or crusting. If any of these occur, discontinue use immediately and seek medical attention.

Individuals with known hypersensitivity to azelastine hydrochloride or any component of the spray should avoid using Lastin. Patients with severe nasal obstruction, recent nasal surgery, or those taking monoamine oxidase inhibitors should consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.