Product image of Latacomp (Timolol Maleate, Latanoprost) supplied by GNH India

Latacomp

Active Ingredient:
Timolol Maleate, Latanoprost
Origin:
EU

Latacomp (Timolol Maleate, Latanoprost)

Timolol maleate, the active ingredient in Latacomp, is a beta‑blocker/prostaglandin analog combination presented as eye drops for ocular use. It treats open‑angle glaucoma and ocular hypertension by lowering intra‑ocular pressure.
GNH India supplies Latacomp as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ratiopharm Gmbh

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Indications & Clinical Uses

Latacomp is used in ophthalmology to manage conditions that require reduction of intra‑ocular pressure.

  • Open‑angle glaucoma: lowers intra‑ocular pressure to prevent optic nerve damage.
  • Ocular hypertension: reduces pressure to lower the risk of progression to glaucoma.
  • Post‑surgical pressure control: helps maintain target pressure after glaucoma surgery.

How It Works

  • Timolol maleate reduces aqueous humor production by non‑selective β‑adrenergic blockade of ciliary body receptors, while latanoprost, a prostaglandin F2α analog, increases uveoscleral outflow of aqueous humor. The combined actions result in a greater and sustained decrease in intra‑ocular pressure.

Side Effects

Adverse reactions may occur with the use of Latacomp.

Common Side Effects

  • Eye irritation: mild burning or stinging after instillation.
  • Blurred vision: temporary visual disturbance.
  • Eye redness: conjunctival hyperemia.
  • Increased eyelash growth: longer, thicker lashes.
  • Darkening of iris: gradual pigmentation change.
  • Foreign body sensation: feeling of something in the eye.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, rash, or difficulty breathing.
  • Worsening glaucoma: unexpected rise in intra‑ocular pressure.
  • Ocular inflammation: uveitis or keratitis.
  • Systemic bradycardia: slowed heart rate.
  • Hypotension: notable drop in blood pressure.
  • Stevens‑Johnson syndrome: rare but serious skin reaction.

Precautions & Warnings

Before using Latacomp, consider the following safety measures.

  • Pregnancy: consult a healthcare provider as safety has not been established.
  • Breastfeeding: avoid unless benefits outweigh potential risks.
  • Cardiovascular disease: monitor heart rate and blood pressure regularly.
  • Respiratory disease: use with caution in patients with asthma or COPD.
  • Drug interactions: avoid concomitant non‑selective beta‑blockers.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Latacomp may interact with other medications; review the following categories.

Major Interactions (Avoid)

  • Non‑selective beta‑blockers: additive systemic beta‑blockade.
  • Calcium channel blockers: may enhance hypotensive effect.
  • MAO inhibitors: increased risk of bradycardia.
  • Other prostaglandin analogs: risk of additive ocular effects.

Moderate Interactions (Monitor Closely)

  • Systemic antihypertensives: monitor blood pressure.
  • Bronchodilators: watch for bronchospasm.
  • Topical ocular anesthetics: may increase corneal toxicity.

Frequently Asked Questions

Latacomp is an ophthalmic solution that combines timolol maleate and latanoprost to lower intra‑ocular pressure. It is prescribed for patients with open‑angle glaucoma or ocular hypertension to help prevent optic nerve damage and preserve vision.

Timolol maleate is a non‑selective beta‑blocker that reduces the production of aqueous humor by blocking β‑adrenergic receptors in the ciliary body. This decrease in fluid formation contributes to lower intra‑ocular pressure.

The dosing regimen for Latacomp is determined by the prescribing ophthalmologist based on the individual’s condition and response. Typically, one drop is instilled in the affected eye(s) once daily, but the exact schedule should follow the clinician’s instructions.

Safety of Latacomp in pregnancy and lactation has not been fully established. Healthcare providers should weigh potential benefits against risks and discuss options with the patient before initiating therapy.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Latacomp combines two mechanisms—beta‑blockade and prostaglandin analog activity—offering a greater intra‑ocular pressure reduction than many single‑agent therapies. This can simplify treatment regimens compared with using separate timolol and latanoprost products.

Latacomp should be stored at room temperature, below 25 °C, in its original packaging. Protect the bottle from direct light and moisture to maintain stability and potency.

Latacomp is applied as an eye drop. The patient should wash hands, tilt the head back, pull down the lower eyelid, and place a single drop into the conjunctival sac of each prescribed eye, avoiding contact between the tip and the eye.

Serious risks include severe allergic reactions, a sudden increase in intra‑ocular pressure, ocular inflammation, systemic bradycardia, and hypotension. Patients should seek immediate medical attention if they experience symptoms such as swelling, rash, rapid heartbeat changes, or vision loss.

Latacomp is contraindicated in patients with known hypersensitivity to timolol, latanoprost, or any component of the formulation, as well as those with severe sinus bradycardia, advanced heart block, or uncontrolled asthma. A healthcare professional should evaluate suitability before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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