Product image of Latafix (Timolol Maleate, Latanoprost) supplied by GNH India

Latafix

Active Ingredient:
Timolol Maleate, Latanoprost
Origin:
EU

Latafix (Timolol Maleate, Latanoprost)

Timolol maleate and Latanoprost, the active ingredients in Latafix, are a beta‑blocker and a prostaglandin analog presented as eye drops for ocular use. They are indicated for the reduction of intra‑ocular pressure in patients with glaucoma or ocular hypertension.
GNH India supplies Latafix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Doc Generici S.R.L.

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Indications & Clinical Uses

Latafix is an antiglaucoma combination that lowers intra‑ocular pressure in several ocular conditions.

  • Open‑angle glaucoma: reduces eye pressure to prevent optic nerve damage.
  • Ocular hypertension: lowers intra‑ocular pressure to reduce the risk of progression to glaucoma.
  • Secondary glaucoma (e.g., steroid‑induced): helps control pressure when other agents are insufficient.

How It Works

  • Timolol maleate lowers intra‑ocular pressure by blocking β‑adrenergic receptors in the ciliary body, decreasing aqueous humor production. Latanoprost activates prostaglandin F receptors, enhancing uveoscleral outflow of aqueous humor. The combined actions result in a synergistic reduction of intra‑ocular pressure.

Side Effects

Latafix may cause a range of ocular and systemic reactions.

Common Side Effects

  • Eye irritation: mild burning or stinging on instillation.
  • Blurred vision: temporary visual disturbance after dosing.
  • Eye redness: conjunctival hyperemia.
  • Dry eye: reduced tear production.
  • Headache: mild, transient.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, rash, or anaphylaxis.
  • Significant reduction in heart rate: bradycardia.
  • Exacerbation of asthma: bronchospasm.
  • Iridocyclitis: intra‑ocular inflammation.

Precautions & Warnings

Before prescribing Latafix, consider the following safety measures.

  • Contraindicated in patients with known hypersensitivity to timolol, latanoprost or any component of the formulation.
  • Use with caution in patients with asthma or chronic obstructive pulmonary disease.
  • Monitor heart rate and blood pressure in patients with cardiac disease.
  • Avoid concurrent use with other beta‑blocker eye drops.
  • Pregnancy and lactation: safety not established; use only if benefit outweighs risk.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Latafix can interact with systemic and ocular medications.

Major Interactions (Avoid)

  • Systemic beta‑blockers: additive bradycardia and hypotension.
  • Non‑selective beta‑blocker inhalers: increased risk of bronchospasm.
  • MAO inhibitors: potential for severe hypertension.

Moderate Interactions (Monitor Closely)

  • Other prostaglandin analogues: additive ocular effects.
  • Topical ocular anesthetics: may increase corneal toxicity.
  • Anticholinergic agents: may affect pupil response.

Frequently Asked Questions

Latafix is a prescription eye‑drop formulation that combines timolol maleate and latanoprost to lower intra‑ocular pressure. It is approved for the treatment of open‑angle glaucoma and ocular hypertension, helping to prevent optic nerve damage and preserve visual function.

Timolol maleate blocks β‑adrenergic receptors in the eye, reducing the production of aqueous humor. Latanoprost activates prostaglandin F receptors, increasing uveoscleral outflow of fluid. Together, they provide a dual mechanism that effectively lowers eye pressure.

The dosing regimen for Latafix is determined by a qualified eye‑care professional. Typically, one drop is instilled in the affected eye(s) once daily, but the exact dose and frequency must be individualized by the prescriber based on the patient’s condition.

Safety data for Latafix in pregnancy and lactation are limited. It should only be used when the potential benefit justifies the potential risk to the fetus or infant, and this decision must be made by the treating physician.

To order Latafix, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Latafix combines a beta‑blocker and a prostaglandin analog, offering a synergistic pressure‑lowering effect that can be more effective than using either class alone. Compared with monotherapy, the combination may reduce the need for multiple separate eye drops, improving adherence.

Latafix should be stored at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed when not in use and retain it in the original packaging to protect the formulation from contamination.

Latafix is applied as an ocular solution. The patient should wash their hands, tilt the head back, pull down the lower eyelid, and place one drop into the conjunctival sac. Close the eye gently and avoid blinking excessively for a few seconds.

Serious adverse reactions include severe allergic responses such as swelling or anaphylaxis, significant bradycardia, bronchospasm in susceptible individuals, and intra‑ocular inflammation (iridocyclitis). Any of these symptoms require immediate medical attention.

Latafix is contraindicated in patients with known hypersensitivity to timolol, latanoprost, or any excipients in the formulation. It should also be avoided in individuals with severe asthma, certain cardiac conditions, or those using other beta‑blocker eye drops without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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