Product image of Latanea (Latanoprost) supplied by GNH India

Latanea

Active Ingredient:
Latanoprost
Origin:
EU

Latanea (Latanoprost)

Latanoprost, the active ingredient in Latanea, is a prostaglandin analog presented as an ophthalmic solution for ocular use. It lowers intra‑ocular pressure and is used in the management of glaucoma and ocular hypertension in adult patients.

GNH India supplies Latanea as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Horus Pharma

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Indications & Clinical Uses

Latanoprost is employed in the prostaglandin analog class to reduce intra‑ocular pressure in several glaucoma‑related conditions.

  • Primary open‑angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers eye pressure to prevent conversion to glaucoma.
  • Secondary open‑angle glaucoma (including pseudoexfoliative glaucoma): helps control pressure when other mechanisms are involved.

How It Works

  • Latanoprost is a synthetic analogue of prostaglandin F₂α that binds to FP receptors in the ciliary body. Activation of these receptors remodels the extracellular matrix, enhancing uveoscleral outflow of aqueous humor. The increased outflow reduces intra‑ocular pressure, providing therapeutic control of glaucoma and ocular hypertension.

Side Effects

Latanoprost may cause ocular and peri‑ocular reactions, most of which are mild and reversible.

Common Side Effects

  • Eye redness (hyperemia): mild conjunctival injection.
  • Increased iris pigmentation: gradual darkening of the iris.
  • Eyelash changes: longer, thicker, or darker lashes.
  • Ocular irritation: burning or stinging sensation.
  • Dry eye sensation: transient dryness or foreign body feeling.

Serious or Rare Side Effects

  • Uveitis or iritis: inflammation of the uveal tract.
  • Macular edema: swelling of the central retina.
  • Iris or retinal cyst formation: rare proliferative lesions.
  • Severe allergic reaction: swelling, itching, or rash around the eye.

Precautions & Warnings

When prescribing latanoprost, clinicians should observe several safety considerations.

  • Monitor intra‑ocular pressure: assess response after initiation.
  • Evaluate ocular surface: check for pre‑existing inflammation or infection.
  • Avoid use in active ocular infection: postpone treatment until resolved.
  • Caution in patients with a history of herpetic keratitis: monitor for reactivation.
  • Discontinue if severe inflammation or macular edema develops: seek ophthalmologic evaluation.
  • Store at room temperature below 25 °C: keep in original container, protect from light and moisture.

Avoid Interactions

Latanoprost can interact with other ocular or systemic agents, influencing efficacy or safety.

Major Interactions (Avoid)

  • Concomitant use with other prostaglandin analog eye drops: may increase risk of ocular hyperemia and pigmentation changes.
  • Use with topical non‑steroidal anti‑inflammatory drugs (NSAIDs): can exacerbate ocular irritation.

Moderate Interactions (Monitor Closely)

  • Combination with carbonic anhydrase inhibitors or beta‑blocker eye drops: additive intra‑ocular pressure‑lowering effect, monitor pressure closely.
  • Systemic use of immunosuppressants: may alter ocular healing response.
  • Anticholinergic agents: potential for reduced tear production, monitor for dry eye.

Frequently Asked Questions

Latanea contains latanoprost, a prostaglandin analog indicated to lower intra‑ocular pressure in adults with primary open‑angle glaucoma, ocular hypertension, and certain secondary open‑angle glaucomas. By reducing eye pressure, it helps prevent optic nerve damage and visual field loss associated with these conditions.

Latanoprost mimics prostaglandin F₂α and binds to FP receptors in the ciliary body. This triggers remodeling of extracellular matrix proteins, which enhances the uveoscleral outflow pathway for aqueous humor. The increased outflow lowers intra‑ocular pressure, providing therapeutic benefit in glaucoma and ocular hypertension.

The prescribed dose of latanoprost is determined by the treating ophthalmologist. Typically, one drop of the ophthalmic solution is instilled into the affected eye(s) once daily, usually in the evening, but the exact regimen should follow the prescriber’s instructions.

Safety of latanoprost in pregnancy and lactation has not been established. It should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To order Latanea, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Latanoprost is often preferred for its once‑daily dosing and strong intra‑ocular pressure‑lowering effect. Compared with beta‑blockers, it has fewer systemic cardiovascular effects; versus carbonic anhydrase inhibitors, it avoids taste disturbances. However, prostaglandin analogs can cause ocular pigmentation changes, which are less common with other classes.

Latanea should be stored at room temperature below 25 °C, in its original container, protected from light and moisture. Do not freeze the product. Keep the bottle tightly closed when not in use and avoid contaminating the tip of the dropper.

Latanea is an ophthalmic solution. The patient should wash hands, tilt the head back, pull down the lower eyelid, and place one drop into the conjunctival sac without touching the tip to the eye or lashes. Close the eye gently for a few minutes and avoid blinking excessively.

Serious but rare risks include uveitis or iritis, macular edema, formation of iris or retinal cysts, and severe allergic reactions such as swelling or rash around the eye. If any of these occur, the patient should discontinue use and seek immediate ophthalmologic evaluation.

Latanea should not be used by individuals with known hypersensitivity to latanoprost or any excipients, or by patients with active ocular infections or inflammation until these conditions are resolved. Caution is also advised for patients with a history of herpetic keratitis or severe ocular surface disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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