Product image of Latanoprost Actavis (Latanoprost) supplied by GNH India

Latanoprost Actavis

Active Ingredient:
Latanoprost
Origin:
EU

Latanoprost Actavis (Latanoprost)

Latanoprost, the active ingredient in Latanoprost Actavis, is a prostaglandin analog presented as a topical ophthalmic solution for ocular use. It lowers intra‑ocular pressure and is used in the management of open‑angle glaucoma and ocular hypertension in adult patients.

GNH India supplies Latanoprost Actavis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Latanoprost Actavis belongs to the prostaglandin analog class and is used to manage conditions that involve elevated intra‑ocular pressure.

  • Open‑angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers pressure to prevent conversion to glaucoma.
  • Secondary open‑angle glaucoma: helps control pressure when caused by other ocular conditions.

How It Works

  • Latanoprost is a prostaglandin F2α analogue that binds to FP receptors in the ciliary muscle, enhancing uveoscleral outflow of aqueous humor. By increasing this unconventional drainage pathway, the drug effectively reduces intra‑ocular pressure, thereby helping to preserve optic nerve function in glaucomatous eyes.

Side Effects

Latanoprost may cause ocular and systemic reactions, most of which are mild and reversible.

Common Side Effects

  • Eye redness: mild conjunctival hyperemia.
  • Itching or burning sensation: transient ocular discomfort.
  • Increased iris pigmentation: gradual darkening of the iris color.
  • Eyelash growth: longer, thicker lashes.
  • Blurred vision: temporary visual disturbance after instillation.
  • Eye discharge: mild tearing or watery eyes.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, rash, or difficulty breathing.
  • Eye pain or severe irritation: may indicate inflammation.
  • Vision loss: sudden decrease in visual acuity.
  • Uveitis or iritis: intra‑ocular inflammation requiring medical attention.
  • Corneal edema: swelling of the cornea affecting clarity.
  • Periorbital fat atrophy: loss of orbital fat tissue.

Precautions & Warnings

Before using Latanoprost Actavis, consider the following safety measures.

  • Pregnancy: safety not established; avoid unless clearly needed.
  • Breastfeeding: unknown excretion; weigh benefits against potential risks.
  • Active ocular inflammation: contraindicated until inflammation resolves.
  • Intra‑ocular pressure monitoring: assess response after initiation.
  • Concomitant eye drops: wait at least 5 minutes between applications.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Latanoprost may interact with other ocular or systemic agents.

Major Interactions (Avoid)

  • Other prostaglandin analogs (e.g., bimatoprost): additive pressure‑lowering effect may cause excessive reduction.
  • Ocular anesthetics: increased risk of corneal irritation.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory eye drops: may alter ocular surface tolerance.
  • Systemic beta‑blockers: additive intra‑ocular pressure reduction.
  • Anticholinergic agents: potential impact on tear production.
  • Topical corticosteroids: may diminish Latanoprost efficacy.

Frequently Asked Questions

Latanoprost Actavis is a prescription eye drop containing the prostaglandin analogue latanoprost. It is used to lower intra‑ocular pressure in adults with open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve vision.

Latanoprost mimics prostaglandin F2α and activates FP receptors in the eye’s ciliary muscle. This activation increases uveoscleral outflow of aqueous humor, the fluid that maintains eye pressure, thereby reducing intra‑ocular pressure and slowing glaucoma progression.

The dosing regimen for Latanoprost Actavis is determined by the prescribing clinician. Typically, one drop is instilled into the affected eye(s) once daily in the evening, but the exact dose and timing must follow the prescriber’s instructions.

Safety of latanoprost in pregnancy and lactation has not been established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by the treating physician.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Latanoprost belongs to the prostaglandin analogue class, which generally provides greater and more consistent intra‑ocular pressure reduction than beta‑blockers or carbonic anhydrase inhibitors. It is often preferred as first‑line therapy because of once‑daily dosing and a favorable efficacy profile.

Latanoprost Actavis should be stored at room temperature, below 25 °C, in its original container. Keep the bottle tightly closed, protect it from light and moisture, and discard any solution that has changed in appearance.

The medication is applied topically as an eye drop. The patient should wash hands, tilt the head back, pull down the lower eyelid, and place one drop into the conjunctival sac. Close the eye gently and avoid blinking excessively for a few seconds.

Serious risks include severe allergic reactions, significant eye pain, sudden vision loss, uveitis, iritis, corneal edema, and marked changes in iris pigmentation. Any sudden or severe ocular symptoms should prompt immediate medical evaluation.

Patients with active ocular inflammation, known hypersensitivity to latanoprost or any component of the formulation, or those who have experienced severe adverse reactions to prostaglandin analogues should not use this product. Consultation with an eye‑care professional is essential.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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