Product image of Latanoprost Actavis (Latanoprost) supplied by GNH India

Latanoprost Actavis

Active Ingredient:
Latanoprost
Origin:
EU

Latanoprost Actavis (Latanoprost)

Latanoprost, the active ingredient in Latanoprost Actavis, is a prostaglandin F2α analog presented as an ophthalmic solution for ocular administration. It is indicated for the reduction of intra‑ocular pressure in primary open‑angle glaucoma and ocular hypertension, primarily in adult patients.

GNH India supplies Latanoprost Actavis as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics worldwide. The company ensures quality control, regulatory compliance, and reliable global logistics for this prescription‑only medication.

Manufacturer / TM Owner

Actavis Group Ptc Ehf.

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Indications & Clinical Uses

Latanoprost is a prostaglandin analog used to lower intra‑ocular pressure in glaucoma‑related conditions.

  • Primary open‑angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers eye pressure to prevent development of glaucoma.
  • Pseudoexfoliative glaucoma: decreases pressure to protect the optic nerve.
  • Pigmentary glaucoma: helps control intra‑ocular pressure and preserve visual function.

How It Works

  • Latanoprost binds to prostaglandin F (FP) receptors in the ciliary body, activating a cascade that remodels extracellular matrix and enhances uveoscleral outflow of aqueous humor. This increased outflow reduces intra‑ocular pressure, thereby helping to prevent optic nerve damage associated with glaucoma.

Side Effects

Latanoprost may cause ocular and systemic reactions.

Common Side Effects

  • Increased iris pigmentation: gradual darkening of the iris color.
  • Eyelash changes: longer, thicker, or darker eyelashes.
  • Eye redness: mild conjunctival hyperemia.
  • Eye irritation: transient burning or stinging after instillation.

Serious or Rare Side Effects

  • Severe allergic reaction: conjunctivitis or swelling of the eyelids.
  • Corneal edema: swelling of the cornea that can impair vision.
  • Macular edema: fluid accumulation in the central retina, potentially reducing visual acuity.

Precautions & Warnings

Before using Latanoprost, consider the following precautions.

  • Pregnancy: safety not established; avoid unless clearly needed.
  • Breastfeeding: unknown safety; weigh potential risks and benefits.
  • Contraindications: do not use in eyes with active inflammation or infection.
  • Monitoring: intra‑ocular pressure should be measured regularly after initiation.
  • Contact lens wearers: may experience deposits; consider removing lenses before application.
  • Store at room temperature: keep bottle in original packaging, protect from light and moisture.

Avoid Interactions

Latanoprost may interact with other ophthalmic agents.

Major Interactions (Avoid)

  • Prostaglandin analogs (e.g., bimatoprost): additive ocular effects.
  • Systemic carbonic anhydrase inhibitors: may reduce IOP‑lowering efficacy.
  • Non‑steroidal anti‑inflammatory eye drops: increased risk of ocular inflammation.

Moderate Interactions (Monitor Closely)

  • Beta‑blocker eye drops: possible additive intra‑ocular pressure reduction.
  • Topical corticosteroids: may diminish Latanoprost’s IOP‑lowering effect.
  • Anticholinergic eye drops: monitor for changes in ocular surface health.

Frequently Asked Questions

Latanoprost Actavis is prescribed to lower intra‑ocular pressure in adults with primary open‑angle glaucoma and ocular hypertension. By reducing eye pressure, it helps slow disease progression and lowers the risk of optic nerve damage.

Latanoprost activates prostaglandin F (FP) receptors in the eye’s ciliary body, which remodels extracellular matrix and enhances uveoscleral outflow of aqueous humor. This increased drainage lowers intra‑ocular pressure, addressing the underlying cause of glaucoma.

The dosing regimen for Latanoprost Actavis is determined by the prescribing clinician. Typically, one drop is instilled into the affected eye(s) once daily in the evening, but the exact dose and schedule must follow the prescriber’s instructions.

Safety data for Latanoprost in pregnancy and lactation are limited. The product is classified as pregnancy category unknown, so it should only be used if the potential benefit justifies the potential risk. Breastfeeding mothers should consult their healthcare provider before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Latanoprost belongs to the prostaglandin analog class, which generally offers once‑daily dosing and strong IOP‑lowering efficacy. Compared with beta‑blocker drops, it often provides greater pressure reduction with fewer systemic side effects, though individual response can vary.

Latanoprost Actavis should be stored at room temperature, below 25 °C. Keep the bottle in its original packaging, protect it from light and moisture, and avoid freezing. Do not refrigerate unless otherwise directed by the manufacturer.

Latanoprost Actavis is an ophthalmic solution applied as a single drop into the affected eye(s) once daily, preferably in the evening. Patients should wash their hands, avoid touching the tip of the bottle, and wait a few minutes before applying other eye medications.

Serious but rare risks include severe allergic reactions such as conjunctivitis, corneal edema, macular edema, and vision loss. Any sudden change in vision, eye pain, or severe redness should prompt immediate medical evaluation.

Latanoprost should not be used in patients with active ocular infection or inflammation, hypersensitivity to prostaglandin analogs, or in individuals where the prescriber determines the risks outweigh the benefits. Consultation with an eye care professional is essential before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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