Product image of Latanoprost Actavis (Latanoprost) supplied by GNH India

Latanoprost Actavis

Active Ingredient:
Latanoprost
Origin:
EU

Latanoprost Actavis (Latanoprost)

Latanoprost, the active ingredient in Latanoprost Actavis, is a prostaglandin F2α analog presented as a topical ophthalmic solution for ocular use. It is employed to lower intra‑ocular pressure in patients with open‑angle glaucoma or ocular hypertension.
GNH India supplies Latanoprost Actavis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Actavis Group Ptc Ehf.

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Indications & Clinical Uses

Latanoprost is a prostaglandin analog used to manage conditions that involve elevated intra‑ocular pressure.

  • Open‑angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers eye pressure to prevent conversion to glaucoma.
  • Elevated intra‑ocular pressure (IOP): achieves sustained pressure reduction to protect optic nerve health.

How It Works

  • Latanoprost acts as an agonist at prostaglandin F (FP) receptors in the ciliary body, enhancing uveoscleral outflow of aqueous humor. By increasing this unconventional drainage pathway, the drug lowers intra‑ocular pressure, thereby reducing stress on the optic nerve and helping to preserve visual function.

Side Effects

Latanoprost may cause ocular and peri‑ocular reactions.

Common Side Effects

  • Eye redness: mild conjunctival hyperemia.
  • Increased eyelash growth: longer, thicker lashes.
  • Iris darkening: gradual brownish pigmentation change.
  • Eye irritation: transient burning or stinging sensation.

Serious or Rare Side Effects

  • Severe eye inflammation: uveitis or iritis requiring medical attention.
  • Allergic reaction: swelling, itching, or rash around the eye.
  • Macular edema: fluid accumulation in the central retina that can affect vision.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Monitor intra‑ocular pressure: assess response after the first few weeks.
  • Assess for ocular inflammation: discontinue if severe uveitis develops.
  • Avoid use in patients with known hypersensitivity to prostaglandin analogs.
  • Caution in corneal disease: evaluate corneal health prior to treatment.
  • Store at room temperature: keep bottle tightly closed, protect from light and moisture.

Avoid Interactions

Latanoprost may interact with other ocular or systemic agents.

Major Interactions (Avoid)

  • Concurrent use with other prostaglandin analog eye drops: risk of excessive pressure lowering.
  • Use with ocular prostaglandin‑containing formulations: may increase adverse ocular effects.

Moderate Interactions (Monitor Closely)

  • Combination with beta‑blocker eye drops: additive IOP‑lowering effect, monitor pressure.
  • Use with carbonic anhydrase inhibitor eye drops: enhanced pressure reduction, adjust therapy as needed.
  • Co‑administration with corticosteroid eye drops: possible reduction in Latanoprost efficacy, observe response.

Frequently Asked Questions

Latanoprost Actavis is an ophthalmic solution that contains the prostaglandin analog latanoprost. It is prescribed to lower intra‑ocular pressure in adults with open‑angle glaucoma or ocular hypertension, helping to protect the optic nerve and preserve vision.

Latanoprost binds to prostaglandin F (FP) receptors in the eye’s ciliary body, stimulating the uveoscleral outflow pathway. This increased drainage of aqueous humor reduces intra‑ocular pressure, which is the primary therapeutic goal in glaucoma and ocular hypertension.

The dosing regimen for Latanoprost Actavis is determined by the prescribing clinician. Typically, one drop is instilled into the affected eye(s) once daily in the evening, but the exact dose and timing should follow the prescriber’s instructions.

The safety of latanoprost in pregnancy and lactation has not been definitively established. It is classified as pregnancy category unknown, and use should be considered only if the potential benefit justifies any potential risk to the fetus or infant.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Latanoprost belongs to the prostaglandin analog class, which generally provides the greatest IOP‑lowering effect with once‑daily dosing. Compared with beta‑blockers or carbonic anhydrase inhibitors, latanoprost often achieves larger pressure reductions and has a different side‑effect profile, such as increased eyelash growth and iris pigmentation.

Latanoprost Actavis should be stored at room temperature, below 25 °C. Keep the bottle tightly closed, protect it from light and moisture, and avoid freezing. Do not refrigerate unless specifically instructed by the manufacturer.

The medication is applied topically as an eye drop. The patient should wash hands, tilt the head back, pull down the lower eyelid to create a small pocket, and place one drop into the conjunctival sac. Close the eye gently and avoid blinking excessively for a few seconds.

Serious risks, though rare, include severe ocular inflammation such as uveitis, allergic reactions that may cause swelling or rash around the eye, and macular edema which can affect central vision. Any sudden vision changes or intense eye pain should prompt immediate medical evaluation.

Patients with known hypersensitivity to latanoprost or any component of the formulation should avoid its use. It is also contraindicated in individuals with active ocular infections or severe inflammation until those conditions are resolved.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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