Product image of Latanoprost Actavis (Latanoprost) supplied by GNH India

Latanoprost Actavis

Active Ingredient:
Latanoprost
Origin:
EU

Latanoprost Actavis (Latanoprost)

Latanoprost, the active ingredient in Latanoprost Actavis, is a prostaglandin analog presented as an ophthalmic solution for ocular use. It lowers intra‑ocular pressure in adults with open‑angle glaucoma or ocular hypertension by increasing fluid outflow from the eye, helping to preserve visual function.

GNH India supplies Latanoprost Actavis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global distribution.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

  • Latanoprost is a prostaglandin analog used to lower intra‑ocular pressure in glaucoma‑related conditions.
  • Open‑angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers eye pressure to prevent development of glaucoma.
  • Secondary open‑angle glaucoma: helps control pressure when other causes are present.
  • Normal‑tension glaucoma: assists in maintaining target pressure to protect optic nerve health.

How It Works

  • Latanoprost binds to prostaglandin F‑type receptors in the ciliary body, activating a cascade that remodels the extracellular matrix of the uveoscleral pathway. This remodeling enhances uveoscleral outflow of aqueous humor, thereby decreasing intra‑ocular pressure and reducing stress on the optic nerve.

Side Effects

Latanoprost may cause ocular and systemic reactions, most of which are mild and reversible.

Common Side Effects

  • Eye redness or hyperemia.
  • Increased eyelash length and density.
  • Darkening of the iris color.
  • Eye irritation or foreign‑body sensation.
  • Blurred vision shortly after instillation.
  • Mild eye pain or discomfort.

Serious or Rare Side Effects

  • Severe allergic reaction with swelling of the eyelid or conjunctiva.
  • Uveitis or intra‑ocular inflammation.
  • Macular edema leading to visual disturbance.
  • Persistent eye pain unresponsive to treatment.
  • Sudden loss of vision.
  • Corneal ulceration or infection.

Precautions & Warnings

Before prescribing Latanoprost, clinicians should evaluate patient history and monitor ocular health.

  • Monitor intra‑ocular pressure: assess response after initiation and adjust therapy as needed.
  • Assess for ocular infections: avoid use in active conjunctivitis or keratitis.
  • Use with caution in patients with a history of uveitis or ocular inflammation.
  • Avoid concurrent use with other prostaglandin analog eye drops to prevent additive effects.
  • Pregnancy and lactation: safety not established; use only if benefit outweighs risk.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Latanoprost can interact with other ophthalmic agents, affecting efficacy or safety.

Major Interactions (Avoid)

  • Concomitant use with other prostaglandin analog eye drops: may cause excessive IOP reduction.
  • Use with preservative‑containing NSAID eye drops: increased risk of ocular irritation.

Moderate Interactions (Monitor Closely)

  • Beta‑blocker eye drops: additive intra‑ocular pressure‑lowering effect.
  • Topical corticosteroids: may diminish Latanoprost efficacy.
  • Anticholinergic eye drops: possible reduction in tear production, leading to discomfort.
  • Systemic carbonic anhydrase inhibitors: monitor IOP for synergistic lowering.

Frequently Asked Questions

Latanoprost Actavis is a prescription ophthalmic solution containing the prostaglandin analog latanoprost. It is used to lower intra‑ocular pressure in adults with open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve vision.

Latanoprost binds to prostaglandin F‑type receptors in the eye’s ciliary body, triggering remodeling of the extracellular matrix in the uveoscleral pathway. This remodeling increases the outflow of aqueous humor, thereby decreasing intra‑ocular pressure.

The dosing regimen for Latanoprost Actavis is determined by the prescribing clinician. Typically, one drop is instilled in the affected eye(s) once daily in the evening, but the exact dose and timing should follow the prescriber’s instructions.

Safety data for latanoprost in pregnancy and lactation are limited. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by the treating physician.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Latanoprost belongs to the prostaglandin analog class, which generally offers once‑daily dosing and strong IOP‑lowering efficacy. Compared with beta‑blocker or carbonic anhydrase inhibitor drops, prostaglandin analogs often achieve greater pressure reduction with a convenient dosing schedule, though individual response varies.

Latanoprost Actavis should be stored at ambient temperature, below 25 °C. Keep the bottle in its original packaging, protect it from light and moisture, and discard any solution that appears discolored or cloudy.

The medication is applied as a single drop to the conjunctival sac of the affected eye(s) once daily, usually in the evening. Patients should wash their hands before use, avoid touching the dropper tip to any surface, and close the eye gently after instillation.

Serious risks, though rare, include severe allergic reactions, uveitis, macular edema, corneal ulceration, and sudden loss of vision. Patients should seek immediate medical attention if they experience significant eye pain, vision changes, or signs of infection.

Latanoprost should be avoided in patients with known hypersensitivity to latanoprost or any component of the formulation, in eyes with active inflammation or infection, and in individuals where prostaglandin analogs are contraindicated. A healthcare professional should evaluate suitability before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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