Product image of Latanoprost Actavis (Latanoprost) supplied by GNH India

Latanoprost Actavis

Active Ingredient:
Latanoprost
Origin:
EU

Latanoprost Actavis (Latanoprost)

Latanoprost, the active ingredient in Latanoprost Actavis, is a prostaglandin analog presented as a topical ophthalmic solution for ocular use. It lowers intra‑ocular pressure and is indicated for the management of open‑angle glaucoma and ocular hypertension in adult patients.

GNH India supplies Latanoprost Actavis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company follows EU quality standards and provides reliable global distribution.

Manufacturer / TM Owner

Actavis Group Ptc Ehf.

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Indications & Clinical Uses

Latanoprost is a prostaglandin analog used to reduce intra‑ocular pressure in ocular conditions.

  • Open‑angle glaucoma: reduces intra‑ocular pressure, helping to prevent progression of visual field loss.
  • Ocular hypertension: lowers eye pressure to reduce the risk of developing glaucoma.
  • Secondary open‑angle glaucoma: decreases pressure similarly to primary forms, aiding disease control.

How It Works

  • Latanoprost binds to prostaglandin F (FP) receptors in the ciliary muscle, promoting remodeling of the extracellular matrix and increasing uveoscleral outflow of aqueous humor. This enhanced outflow lowers intra‑ocular pressure, which is the primary therapeutic goal in glaucoma and ocular hypertension management.

Side Effects

Common Side Effects

  • Increased iris pigmentation: gradual darkening of the iris color.
  • Eyelash changes: longer, thicker, or darker eyelashes.
  • Conjunctival hyperemia: mild redness of the eye.
  • Eye irritation: transient burning or stinging after instillation.

Serious or Rare Side Effects

  • Uveitis: inflammation inside the eye requiring immediate medical attention.
  • Corneal edema: swelling of the cornea that can affect vision.
  • Severe allergic reaction: includes swelling, rash, or difficulty breathing.

Precautions & Warnings

Patients should be monitored for ocular changes and systemic considerations.

  • Monitor intra‑ocular pressure: schedule regular ophthalmic examinations.
  • Assess iris color change: inform patients about possible permanent pigmentation.
  • Avoid use in active ocular inflammation: contraindicated in uveitis or infections.
  • Caution in corneal disease: monitor closely for edema or decompensation.
  • Store at room temperature below 25°C: keep in the original container, protect from moisture and light.

Avoid Interactions

Latanoprost may interact with other ocular or systemic agents.

Major Interactions (Avoid)

  • Concurrent prostaglandin analogs: additive pressure‑lowering effect may cause hypotony.
  • Preservative‑containing anesthetic drops: increased ocular irritation.

Moderate Interactions (Monitor Closely):\n- Non‑steroidal anti‑inflammatory eye drops: may exacerbate inflammation.

  • Beta‑blocker eye drops: additive intra‑ocular pressure reduction.
  • Systemic antihistamines: possible reduced ocular absorption.

Frequently Asked Questions

Latanoprost Actavis is an ophthalmic solution containing the prostaglandin analog latanoprost. It is prescribed to lower intra‑ocular pressure in adults with open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve visual function.

Latanoprost binds to FP receptors in the eye’s ciliary muscle, triggering remodeling of extracellular matrix proteins. This process enhances uveoscleral outflow of aqueous humor, thereby reducing intra‑ocular pressure, which is the primary therapeutic target in glaucoma management.

The dosing regimen is determined by the prescribing ophthalmologist. Typically, one drop is instilled in the affected eye(s) once daily in the evening, but the exact dose and timing are individualized based on patient response and clinical judgment.

The pregnancy category for latanoprost is unknown. It should only be used during pregnancy or lactation if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Latanoprost belongs to the prostaglandin analog class, which generally offers once‑daily dosing and strong intra‑ocular pressure reduction. Compared with beta‑blocker eye drops such as timolol, latanoprost often provides greater pressure‑lowering efficacy and a more convenient dosing schedule, though individual response varies.

Store the ophthalmic solution at room temperature below 25 °C. Keep the bottle in its original packaging, protect it from moisture and direct sunlight, and ensure the cap is tightly closed to maintain sterility.

Latanoprost is applied as a single drop to the conjunctival sac of the affected eye(s) in the evening. The patient should wash hands, avoid touching the tip of the bottle to the eye or any surface, and gently close the eye for a few minutes after instillation.

Serious adverse events, although rare, include uveitis, corneal edema, and severe allergic reactions such as swelling or difficulty breathing. Patients should seek immediate medical attention if they experience any of these symptoms.

Latanoprost is contraindicated in patients with active ocular inflammation, such as uveitis or ocular infection, and in individuals with known hypersensitivity to latanoprost or any component of the formulation. Caution is also advised for patients with severe corneal disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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