Product image of Latanoprost Ciclum (Latanoprost) supplied by GNH India

Latanoprost Ciclum

Active Ingredient:
Latanoprost
Origin:
EU

Latanoprost Ciclum (Latanoprost)

Latanoprost, the active ingredient in Latanoprost Ciclum, is a prostaglandin analog presented as a 0.005% ophthalmic solution for ocular use. It is indicated for the management of open‑angle glaucoma and ocular hypertension in adult patients, helping to lower intra‑ocular pressure and preserve visual function.
GNH India supplies Latanoprost Ciclum as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ciclum Farma Unipessoal Lda.

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Indications & Clinical Uses

Latanoprost Ciclum belongs to the prostaglandin analog class and is used to manage conditions that involve elevated intra‑ocular pressure.

  • Open‑angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers eye pressure to prevent development of glaucoma.
  • Post‑surgical ocular pressure control: helps maintain target pressure after ocular surgery.

How It Works

  • Latanoprost is a prostaglandin F2α analog that binds to FP receptors in the ciliary body, promoting remodeling of the extracellular matrix and increasing uveoscleral outflow of aqueous humor. This enhanced outflow reduces intra‑ocular pressure, thereby mitigating the risk of optic nerve damage associated with glaucoma and ocular hypertension.

Side Effects

Latanoprost may cause a range of ocular and systemic reactions.

Common Side Effects

  • Eye redness: mild conjunctival hyperemia.
  • Eyelash changes: increased length, thickness, or darkness.
  • Eye irritation: transient burning or stinging on instillation.
  • Blurred vision: temporary visual disturbance.
  • Iris pigmentation: gradual darkening of the iris.
  • Periorbital skin darkening: mild hyperpigmentation around the eye.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, rash, or difficulty breathing.
  • Uveitis: inflammation of the uveal tract.
  • Corneal edema: swelling of the cornea affecting vision.
  • Paradoxical IOP increase: unexpected rise in intra‑ocular pressure.
  • Endophthalmitis: intra‑ocular infection requiring urgent care.
  • Persistent eye pain: may indicate underlying complication.

Precautions & Warnings

Before initiating therapy with Latanoprost Ciclum, consider the following precautions.

  • Baseline assessment: measure intra‑ocular pressure and document iris color.
  • Monitor changes: watch for iris darkening or eyelash growth that may be cosmetically concerning.
  • Ocular infection: avoid use in eyes with active infection or inflammation.
  • History of uveitis: use with caution; monitor for signs of inflammation.
  • Contact lens wear: advise patients to remove lenses before and after instillation.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Latanoprost may interact with other ocular or systemic agents.

Major Interactions (Avoid)

  • Concurrent prostaglandin analogs: additive IOP‑lowering effect may cause hypotony.
  • Systemic carbonic anhydrase inhibitors: excessive reduction of intra‑ocular pressure.

Moderate Interactions (Monitor Closely)

  • Topical ocular NSAIDs: may increase risk of ocular inflammation.
  • Beta‑blocker eye drops: monitor for excessive IOP reduction.
  • Systemic antihistamines: possible dry eye exacerbation.

Frequently Asked Questions

Latanoprost Ciclum is a prescription eye drop containing the prostaglandin analog latanoprost. It is used to lower intra‑ocular pressure in adults with open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve vision.

Latanoprost mimics prostaglandin F2α and binds to FP receptors in the eye’s ciliary body. This triggers remodeling of the extracellular matrix, enhancing uveoscleral outflow of aqueous humor, which reduces intra‑ocular pressure.

The dosing regimen for Latanoprost Ciclum is determined by the prescribing clinician. Typically, one drop is instilled into the affected eye(s) once daily in the evening, but the exact dose and timing must follow the prescriber’s instructions.

Safety data for latanoprost in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by the treating physician.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Latanoprost belongs to the prostaglandin analog class, which generally provides greater IOP reduction with once‑daily dosing compared with beta‑blockers or carbonic anhydrase inhibitors. It is often preferred for its efficacy and convenient dosing schedule.

Store the ophthalmic solution at room temperature, below 25 °C, in the original container. Protect it from moisture and direct light to maintain stability and potency.

Latanoprost Ciclum is applied as a single drop into the conjunctival sac of the affected eye(s) once daily, preferably in the evening. Patients should wash their hands before use, avoid touching the tip to the eye or any surface, and close the eye gently after instillation.

Serious risks include severe allergic reactions, uveitis, corneal edema, and paradoxical increase in intra‑ocular pressure. Any sudden eye pain, vision loss, or signs of infection should prompt immediate medical attention.

Latanoprost Ciclum should not be used in patients with known hypersensitivity to latanoprost or any component of the formulation, in eyes with active infection or inflammation, and caution is advised for individuals with a history of uveitis or severe ocular surface disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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