Product image of Latanoprost Ciclum (Latanoprost) supplied by GNH India

Latanoprost Ciclum

Active Ingredient:
Latanoprost
Origin:
EU

Latanoprost Ciclum (Latanoprost)

Latanoprost, the active ingredient in Latanoprost Ciclum, is a prostaglandin analog presented as an ophthalmic solution for ocular use. It treats primary open-angle glaucoma and ocular hypertension in adults.

GNH India supplies Latanoprost Ciclum as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ciclum Farma Unipessoal Lda.

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Indications & Clinical Uses

Latanoprost is indicated for ocular conditions that require reduction of intra‑ocular pressure.

  • Primary open‑angle glaucoma: lowers intra‑ocular pressure to slow visual field loss.
  • Ocular hypertension: reduces intra‑ocular pressure to prevent progression to glaucoma.
  • Secondary open‑angle glaucoma: helps control pressure when other therapies are insufficient.

How It Works

  • Latanoprost binds to prostaglandin F (FP) receptors in the ciliary muscle, activating a cascade that remodels the extracellular matrix and enhances uveoscleral outflow of aqueous humor, thereby decreasing intra‑ocular pressure.

Side Effects

Latanoprost may cause ocular and systemic reactions.

Common Side Effects

  • Eye redness: mild conjunctival hyperemia.
  • Increased eyelash growth: longer, thicker lashes.
  • Iris darkening: gradual pigmentation change.
  • Eye irritation: burning or stinging sensation.
  • Blurred vision: transient visual disturbance.
  • Foreign body sensation: feeling of grit in the eye.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, rash, or difficulty breathing.
  • Uveitis: inflammation of the uveal tract.
  • Macular edema: fluid accumulation in the retina.
  • Paradoxical increase in intra‑ocular pressure.
  • Corneal ulcer or keratitis.
  • Persistent eye pain or vision loss.

Precautions & Warnings

Before using Latanoprost, consider the following safety measures.

  • Monitor intra‑ocular pressure: assess response after initiation.
  • Assess for ocular infections: avoid use if active infection is present.
  • Evaluate hypersensitivity: discontinue if allergic signs appear.
  • Use with caution in corneal disease: may exacerbate epithelial defects.
  • Avoid in active ocular inflammation: could worsen condition.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Latanoprost can interact with other ophthalmic and systemic agents.

Major Interactions (Avoid)

  • Concomitant prostaglandin analogs: increased risk of ocular side effects.
  • Ophthalmic steroids: may reduce Latanoprost efficacy.
  • Non‑steroidal anti‑inflammatory eye drops: potential for heightened inflammation.

Moderate Interactions (Monitor Closely)

  • Systemic beta‑blockers: additive hypotensive effect.
  • Systemic prostaglandin analogs: possible increased systemic exposure.
  • Contact lens solutions: may affect drug stability and absorption.

Frequently Asked Questions

Latanoprost Ciclum is used to lower intra‑ocular pressure in adults with primary open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve visual function.

Latanoprost activates prostaglandin F (FP) receptors in the eye, which remodels the extracellular matrix and increases uveoscleral outflow of aqueous humor, resulting in reduced intra‑ocular pressure.

The prescribed dose of Latanoprost is determined by the treating ophthalmologist. Typically, one drop is instilled into the affected eye(s) once daily in the evening, but exact dosing should follow the prescriber’s instructions.

Safety data for Latanoprost in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Latanoprost belongs to the prostaglandin analog class, which generally offers once‑daily dosing and strong intra‑ocular pressure reduction. Compared with beta‑blockers or carbonic anhydrase inhibitors, prostaglandin analogs often have a more favorable dosing schedule and comparable efficacy.

Latanoprost should be stored at room temperature, below 25 °C, in its original container. Protect the bottle from moisture and direct sunlight, and keep the cap tightly closed when not in use.

Latanoprost is administered as an eye drop. The patient should wash their hands, tilt the head back, pull down the lower eyelid, and place a single drop into the conjunctival sac, avoiding contact between the tip and the eye or any surface.

Serious risks include severe allergic reactions, uveitis, macular edema, and paradoxical increase in intra‑ocular pressure. Any sudden vision changes, eye pain, or signs of infection should prompt immediate medical evaluation.

Latanoprost should not be used by individuals with active ocular infection, inflammation, or hypersensitivity to the drug or its excipients. Patients with corneal epithelial defects or severe ocular surface disease should also avoid its use unless directed by a specialist.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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