Product image of Latanoprost Combix (Latanoprost) supplied by GNH India

Latanoprost Combix

Active Ingredient:
Latanoprost
Origin:
EU

Latanoprost Combix (Latanoprost)

Latanoprost, the active ingredient in Latanoprost Combix, is a prostaglandin analog presented as an ophthalmic solution for ocular use. It lowers intra‑ocular pressure and is indicated for open‑angle glaucoma and ocular hypertension in adult patients.
GNH India supplies Latanoprost Combix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratorios Combix, S.L.U.

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Indications & Clinical Uses

  • Latanoprost Combix belongs to the prostaglandin analog class and is used to manage conditions that involve elevated intra‑ocular pressure.
  • Open‑angle glaucoma: reduces intra‑ocular pressure to slow optic nerve damage.
  • Ocular hypertension: lowers pressure to prevent progression to glaucoma.
  • Elevated intra‑ocular pressure: improves uveoscleral outflow to maintain normal pressure levels.

How It Works

  • Latanoprost is a prostaglandin F2α analogue that binds to FP receptors in the ciliary muscle, enhancing uveoscleral outflow of aqueous humor. This increased outflow reduces intra‑ocular pressure, helping to protect the optic nerve from pressure‑related damage.

Side Effects

Latanoprost Combix may cause ocular and systemic reactions.

Common Side Effects

  • Eye redness or hyperemia
  • Increased eyelash length or thickness
  • Darkening of the iris pigment
  • Eye irritation or foreign‑body sensation
  • Blurred vision shortly after instillation
  • Mild eye discomfort

Serious or Rare Side Effects

  • Severe allergic reaction (e.g., angio‑edema)
  • Uveitis or intra‑ocular inflammation
  • Corneal edema or keratitis
  • Sudden loss of vision
  • Persistent ocular pain
  • Periorbital skin darkening

Precautions & Warnings

  • Before initiating therapy, clinicians should consider several safety aspects.
  • Monitor intra‑ocular pressure: schedule regular eye examinations to assess efficacy.
  • Assess for ocular infections: avoid use if active conjunctivitis or keratitis is present.
  • Avoid contact lens wear: discontinue lenses during treatment to reduce irritation.
  • Pregnancy and lactation: safety unknown; prescribe only if benefit outweighs potential risk.
  • Drug interactions: inform ophthalmologist of any concurrent ocular medications.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Latanoprost may interact with other ophthalmic agents.

Major Interactions (Avoid)

  • Concomitant use of other prostaglandin analogs: may increase risk of ocular adverse effects.
  • Systemic carbonic anhydrase inhibitors: may diminish intra‑ocular pressure‑lowering effect.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory eye drops: may increase ocular irritation.
  • Beta‑blocker eye drops: additive pressure reduction; monitor IOP closely.
  • Anticholinergic agents: possible reduced efficacy of latanoprost.

Frequently Asked Questions

Latanoprost Combix is prescribed to lower intra‑ocular pressure in patients with open‑angle glaucoma or ocular hypertension. By reducing pressure, it helps to prevent optic nerve damage and preserve visual function.

Latanoprost is a prostaglandin F2α analogue that activates FP receptors in the eye’s ciliary muscle. This activation increases uveoscleral outflow of aqueous humor, thereby lowering intra‑ocular pressure.

The dosing regimen is determined by the prescribing eye‑care professional. Typically, one drop is instilled into the affected eye(s) once daily in the evening, but the exact schedule should follow the prescriber’s instructions.

Safety data for latanoprost in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and only under medical supervision.

Enquiries are submitted via the product page on gnhindia.com, where you specify the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Latanoprost belongs to the prostaglandin analogue class, which generally offers once‑daily dosing and strong pressure‑lowering efficacy. Compared with beta‑blockers such as timolol, latanoprost often provides greater IOP reduction with a different side‑effect profile, making it a first‑line option for many patients.

Store the ophthalmic solution at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed and retain it in the original packaging until use to maintain sterility.

The medication is applied as a single drop into the conjunctival sac of the prescribed eye(s) once daily, usually in the evening. Patients should wash their hands before use and avoid touching the tip of the bottle to any surface.

Serious adverse events, although rare, include severe allergic reactions, uveitis, corneal edema, and sudden loss of vision. Any sudden eye pain, redness, or visual changes should prompt immediate medical evaluation.

Patients with known hypersensitivity to latanoprost or any component of the formulation should avoid the product. It is also contraindicated in eyes with active inflammation or infection until the condition is resolved.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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